Publications
- Top Ten Papers
- Original Papers
- Annual Reports
- Reviews
- Letters
- Books
- Book Chapters
- Book of the Year
- Talks
Top Ten Papers
Doctoral students as co-authors are underlined
1. Boehmer D, Formisano S, de Oliveira Mann C, Mueller S, Kluge M, Metzger P, Rohlfs M, Hörth Ch, Kocheise L, Lichtenthaler S, Hopfner KP, Endres S, Rothenfusser S, Friedel C, Duewell P, Schnurr* M, Koenig* L.
OAS1/RNase L executes RIG-I ligand-dependent tumor cell apoptosis.
Science Immunology 2021; 61, eabe2550.
JIF2021 30.6
https://immunology.sciencemag.org/content/6/61/eabe2550
https://www.lmu-klinikum.de/aktuelles/pressemitteilungen/programmierter-zelltod-von-tumorzellen-durch-synthetische-rna-molekule/3b1205f11defadda

2. Di Pilato M*, Kfuri-Rubens R*, Pruessmann J*, Ozga AJ*, Messemaker M, Cadilha B, Sivakumar R, Cianciaruso Ch, Warner RD, Marangoni F, Carrizosa E, Lesch S, Billingsley J, Perez-Ramos D, Zavala F, Rheinbay E, Luster AD, Gerner MY, Kobold S, Pittet MJ, Mempel TR.
CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment.
Cell 2021, 184:4512-30.
JIF2021 66.8
https://www.sciencedirect.com/science/article/abs/pii/S0092867421008564?dgcid=coauthor
*contributed equally

3. Lesch S, Blumenberg V, Stoiber S, Gottschlich A, Ogonek J, Cadilha B, Dantes Z, Rataj F, Dorman K, Lutz J, Karches C, Heise C, Kurzay M, Larimer B, Grassmann S, Rapp M, Nottebrock A, Kruger S, Tokarew N, Metzger P, Hoerth Ch, Benmebarek MR, Dhoqina D, Gruenmeier R, Seifert M, Oener A, Umut Ö, . . . Rothenfusser S, Duewell P, Koenig L, Schnurr M, Subklewe M, Liss A, Halama N, Reichert M, Mempel T, Endres S, Kobold S.
T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours
Nature Biomedical Engineering 2021; 35:2243-2257.
JIF2020 29.2
https://www.nature.com/articles/s41551-021-00737-6
https://www.lmu-klinikum.de/aktuelles/pressemitteilungen/neue-strategie-gegen-bauchspeicheldrusenkrebs/f95d2c0d7ad55197

4. Kobold* S, Grassmann* S, Chaloupka M, Lampert C, Wenk S, Kraus F, Rapp M, Duewell P, Zeng Y, Schmollinger J, Schnurr M, Endres S#, Rothenfußer S#.
Impact of a new fusion receptor on PD-1-mediated immunosuppression in adoptive T cell therapy.
The Journal of the National Cancer Institute 2015; 107.
JIF 15.2

5. Kobold S, Steffen J, Chaloupka M, Grassmann S, Henkel J, Castoldi R, Zeng Y, Chmielewski M, Schmollinger J, Schnurr M, Rothenfußer S, Schendel DJ, Abken H, Sustmann C, Niederfellner CG, Klein C, Bourquin C, Endres S.
Selective bispecific T cell recruiting antibody enhances anti-tumor activity of adoptive T cell transfer.
The Journal of the National Cancer Institute 2015; 107:364.
JIF 15.2

6. Briukhovetska D, Suarez-Gosalvez J, Voigt C, Markota A, Giannou A, Schuebel M, Jobst J, Zhang T, Doerr J, Mearkl F, Majed L, Meuller PJ, May P, Gottschlich A, Tokarew N, Leucke J, Oener A, Schwerdtfeger M, Andreu-Sanz D, Gruenmeier R, Seifert M, Michaelides S, Hristov M, Koenig LM, Cadilha B, Mikhaylov O, Anders HJ, Rothenfusser S, Flavell R, Cerezo-Wallis D, Tejedo C, Soengas M, Bald T, Huber S, Endres S, Kobold S.
T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis.
Immunity 2023; 143-161.e11.
JIF2021 43.5
https://authors.elsevier.com/sd/article/S107476132200646X

7. Poeck H, Bscheider M, Gross O, Finger K, Roth S, Rebsamen M, Hannesschläger N, Schlee M, Rothenfusser S, Barchet W, Kato H, Akira S, Inoue S, Endres S, Peschel C, Hartmann G, Hornung V, Ruland J.
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production.
Nature Immunology 2010; 11:63-9
JIF 26.2

8. Gross O, Poeck H, Bscheider M, Dostert C, Hannesschlaeger N, Endres S, Tardivel A, Tschopp J, Ruland J.
Syk kinase signaling couples to the Nalp3 inflammasome for anti-fungal host defense.
Nature 2009; 459:433-6
JIF 38.6

9. Hornung V, Ellegast J, Kim S, Brzozka K, Jung A, Kato H, Poeck H, Akira S, Conzel-mann KK, Schlee M, Endres S, Hartmann G.
5’-triphosphate RNA is the ligand for RIG-I.
Science 2006; 314:994-997.
JIF 35.3

10. Hornung V, Guenthner-Biller M, Bourquin C, Ablasser A, Schlee M, Uematsu S, Noronha A, Manoharan M, Akira S, de Fougerolles A, Endres S, Hartmann G.
Sequence-specific potent induction of IFN-a by short interfering RNA in plasmacytoid dendritic cells through TLR7.
Nature Medicine 2005; 11:263-70.
JIF 30.6

Original Papers
Doctoral students as co-authors are underlined (starting in 1998)
2023
213. Lorenzini T et al.
Rational design of PD-1-CD28 ...
British Journal of Cancer 2023, in press.
JIF2021 9.0
213. Märkl F et al.
Bispecific antibodies ...
J Immunother Cancer 2023, in press.
JIF2021 12.5
212. Gottschlich A, Thomas M, Grünmeier R, Lesch S, Rohrbacher L, Igl V, Briukhovetska D, Benmebarek MR, Vick B, Dede S, Müller K, Xu T, Dhoqina D, Märkl F, Robinson S, Sendelhofert A, Schulz H, Umut Ö, Kavaka V, Tsiverioti Ch, Carlini E, Nandi S, Strzalkowski T, Lorenzini T, Stock S, Müller P, Dörr J, Seifert M, Cadilha B, Brabenec R, Röder N, Rataj F, Nüesch M, Modemann F, Wellbrock J, Fiedler W, Kellner Ch, Beltrán E, Herold T, Paquet D, Jeremias I, von Baumgarten L, Endres S, Subklewe M, Marr C, Kobold S.
Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia.
Nature Biotechnology 2023
JIF2021 68.2
211. Wheeler MA, Clark I, Lee HG, Li Z, Linnerbauer M, Rone JM, Blain M, Akl CF , Piester G, Giovannoni F, Charabati M, Lee JH, Kye YC, Choi J, Sanmarco LM, Srun L, Chung EN, Flausino LE , Andersen BM, Rothhammer V, Yano H, Illouz T, Zandee SEJ, Daniel C, Artis D, Prinz M, Abate AR, Kuchroo VK, Antel JP, Prat A, Quintana FJ.
Droplet-based forward genetic screening of astrocyte-microglia cross-talk.
Science 2023; 379:1023-1030.
JIF2021 63.7
211. Tao Xu T, Karschnia P, Cadilha B, Dede S, Lorenz M, Seewaldt N, Nikolaishvili E, Müller K, Blobner J, Teske J, Herold J, Rejeski K, Langer S, Obeck H, Lorenzini T, Mulazzani M, Zhang W, Ishikawa-Ankerhold H, Buchholz V, Subklewe M, Thon N, Straube A, Tonn JC, Kobold S, von Baumgarten L.
In vivo dynamics and anti-tumor effects of EpCAM-directed CAR T-cells against brain metastases from lung cancer.
OncoImmunology 2023; in press.
JIF2021 7.0
211. Giannou A, Kempski J, Shiri AM, Leucke J, Zhang T, Zhao L, Zazara D, Cortesi F, Riecken K, Amezcua Vesely MA, Low JS, Xu H, Kaffe E, Garcia-Perez L, Agalioti T, Yamada Y, Jungraithmayr W, Zigmond E, Karstens KF, Steglich B, Wagner J, Konczalla L, Carambia A, Schulze K, von Felden J, May P, Briukhovetska D, ...Suarez-Gosalvez J, Kobold S, ...Huber S.
Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22.
Immunity 2023; 125–142.
JIF2021 43.5
https://authors.elsevier.com/sd/article/S1074761322006501
211. Briukhovetska D, Suarez-Gosalvez J, Voigt C, Markota A, Giannou A, Schuebel M, Jobst J, Zhang T, Doerr J, Mearkl F, Majed L, Meuller PJ, May P, Gottschlich A, Tokarew N, Leucke J, Oener A, Schwerdtfeger M, Andreu-Sanz D, Gruenmeier R, Seifert M, Michaelides S, Hristov M, Koenig LM, Cadilha B, Mikhaylov O, Anders HJ, Rothenfusser S, Flavell R, Cerezo-Wallis D, Tejedo C, Soengas M, Bald T, Huber S, Endres S, Kobold S.
T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis.
Immunity 2023; 143-161.e11.
JIF2021 43.5
https://authors.elsevier.com/sd/article/S107476132200646X
2022
210. Blaeschke F, Ortner E, Stenger D, Mahdawi J, Apfelbeck A, Habjan N, Weißer T, Kaeuferle T, Willier S, Kobold S, Feuchtinger T.
Design and evaluation of TIM-3-CD28 checkpoint fusion proteins to improve anti-CD19 CAR T-cell function
Frontiers in Immunology 2022; 13:845499.
JIF2021 8.8
210. Demel U, Böger M, Yousefian S, Grunert C, Zhang L, Hotz P, Gottschlich A, Köse H, Isaakidis K, Vonficht D, Grünschläger F, Rohleder E, Wagner K, Dönig J, Igl V, Brzezicha B, Baumgartner F, Habringer S, Löber J, Chapuy J, Weidinger C, Kobold S, Haas S, Busse A, Müller S, Wirth M, Schick M, Keller U.
Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer.
The Journal of Clinical Investigation 2022; 132:e152383.
JIF2021 19.5
210. Lesch S, Nottebrock A, Rataj F, Heise C, Endres S, Kobold S.
PD-1-CD28 fusion protein strengthens mesothelin-specific TRuC T cells in preclinical solid tumor models.
Cellular Oncology 2022; in press.
JIF2021 7.1
https://pubmed.ncbi.nlm.nih.gov/36409438/
209. Summer B, Lill D, Remmel K, Schraml A, Schopf C, IBanke IJ, Kuechenhoff H, Maierhofer T, Endres S, Thomas P.
An interleukin-1 polymorphism additionally intensified by atopy as prognostic factor for aseptic non-mechanical complications in metal knee and hip arthroplasty.
Frontiers in Immunology 2022; in press.
JIF2021 8.8
208. Seifert M, Benmebarek MR, Briukhovetska D, Märkl F, Dörr J, Cadilha B, Jobst J, Stock S, Andreu-Sanz D, Lorenzini T, Grünmeier R, Öner A, Obeck H, Majed L, Dhoqina D, Feinendegen M, Gottschlich A, Zhang J, Schindler U, Endres S, Kobold S.
Impact of the selective A2AR and A2BR dual antagonist AB928/etrumadenant on CAR T cell function.
British Journal of Cancer 2022; 61, eabe2550.
JIF2021 9.1
207. Hölting TLB, Cidre-Aranaz F, Matzek D, Popper B, Jacobi SJ, Funk CM, Geyer FH, Li J, Piseddu I, Cadilha BL, Ledderose S, Zwilling J, Ohmura S, Anz D, Künkele A, Klauschen F, Grünewald TGP, Knott MML.
Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood
sarcoma.
Molecular Cancer 2022, 21:199.
JIF2021 41.4
https://pubmed.ncbi.nlm.nih.gov/36229873/
207. Stazzoni S, Böhmer D, Hernichel F, Özdemir D, Pappa A, Drexler D, Bauernfried S, Witte G, Wagner M, Veth S, Hopfner KP, Hornung V, König LM, Carell T.
Novel poxin stable cGAMP-derivatives are remarkable STING agonists.
Angewandte Chemie 2022; 10:e202207175.
JIF2021 15.3
https://pubmed.ncbi.nlm.nih.gov/35876840/
207. Stock S, Benmebarek MR, Kluever AK, Darowski D, Jost Ch, Stubenrauch KG, Benz J, Freimoser-Grundschober A, Moessner E, Umana P, Subklewe M, Endres S, Klein Ch, Kobold S.
Chimeric antigen receptor T cells engineered to recogniz the P329G- mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting of solid tumors.
Journal for Immunotherapy of Cancer 2022; 10:e005054.
JIF2021 12.5
https://jitc.bmj.com/content/10/7/e005054
206. Bashiri Dezfouli A, Yazdi M, Benmebarek MR, Schwab M, Michaelides S, Miccichè A, Geerts D, Stefan S, Klapproth S, Wagner E, Kobold S, Gabriele Multhoff G.
CAR T cells targeting membrane-bound Hsp70 on tumor cells mimic Hsp70-primed NK cells.
Frontiers in Immunology 2022; 13:883694.
JIF2021 8.8
206. Lücke AC, vom Hemdt A, Wieseler J, Fischer C, Feldmann M, Rothenfusser S, Drexler JF, Kümmerer BM.
High-throughput platform for detection of neutralizing antibodies using flavivirus reporter replicon particles.
Viruses 2022; 4:346.
JIF2021 5.0
206. Arendt K, Ntaliarda G, Armenis V, Kati D, Henning Ch, Giotopoulou G, Pepe M, Klotz L, Lamort A, Hatz R, Kobold S, Schamberger A, Stathopoulos G.
An in vivo inflammatory loop potentiates KRAS blockade.
Biomedicines 2022; 10,592.
JIF2021 6.1
206. Dickopf S, Buldun C, Vasic V, Georges G, Hage C, Mayer K, Forster M, Wessels U, Stubenrauch KG, Benz J, Ehler A, Lauer ME, Ringler P, Kobold S, Endres S, Klein Ch, Brinkmann U.
Prodrug-Activating Chain Exchange (PACE) converts targeted prodrug derivatives to functional bi- or multispecific antibodies.
Biological Chemistry 2022; 403:495-508.
JIF2021 5.2
205. Scheck MK, Lehmann L, Zaucha M, Schwarzlmueller P, Huber K, Pritsch M, Barba-Spaeth G, Thorn-Seshold O, Krug AB, Endres S, Rothenfusser S, Thorn-Seshold J.
FluoRNT: A robust, efficient assay for the detection of neutralising antibodies against yellow fever virus 17D.
PLOS One 2022; 17:e0262149.
JIF2021 3.8
204. Kruger S, Lohneis A, Abendroth A, Berger AW, Ettrich TJ, Waldmann O, Kapp M, Steiber B, Kumbrink J, Reischer A, Haas M, Westphalen CB, Zhang D, Miller-Phillips L, Burger PJ, Kobold S, Werner J, Subklewe M, von Bergwelt-Baildon M, Kunzmann V, Seufferlein T, Siveke JT, Sinn M, Heinemann V, Ormanns S*, Boeck S*.
Prognosis and tumorbiology of pancreatic cancer patients with isolated lung metastases: clinical and translational results from the German multicenter AIO-YMO-PAK-0515 study.
*authors contributed equally
ESMO Open 2022; 7:100388.
JIF2021 6.9
204. Kolorz J, Demir S, Gottschlich A, Beirith I, Ilmer M, Lüthy D, Walz Ch, Dorotskar MM, Magg Th, Hauck F, von Schweinitz D, Kobold S, Kappler R, Berger M.
The neurokinin-1 receptor is a target in pediatric rhabdoid tumors.
Current Oncology 2022; 29:94-110.
JIF2021 3.1
2021
204. Darwich A, Silvestri A, Benmebarek MR, Mouries J, Melacarne A, Cadilha B, Taleb A, Supino D, Obeck H, Sustmann C, Morelli L, Masci G, Losurdo A, Curigliano G, Kobold S, Penna G, Rescigno M.
Paralysis of the cytotoxic granule machinery is a new cancer immune evasion mechanism mediated by Chitinase 3-like-1.
Journal for Immunotherapy of Cancer 2021; 9:e003224.
JIF2020 13.8
204. Cadilha B, Benmebarek MR, Dorman K, Oener A, Lorenzini T, Obeck H, Väntinnen M, Di Pilato M, Pruessmann JN, Stoiber S, Huynh D, Maerkl F, Seifert M, Manske K, Suarez-Gosalvez J, Zeng Y, Lesch S, Karches CH, Heise C, Gottschlich A, Thomas M, Marr C, Zhang J, Pandey D, Feuchtinger T, Subklewe M, Mempel TR, Endres S, Kobold S.
Combined tumor-directed recruitment and protection from immune suppression enable CAR T cell efficacy in solid tumor.
Science Advances 2021; 7:eabi5781.
JIF2020 13.1
https://pubmed.ncbi.nlm.nih.gov/34108220/
203. Winheim E, Rinke L, Lutz K, Reischer A, Leutbecher A, Wolfram L, Rausch L, Kranich J, Wratil PR, Huber JE, Baumjohann D, Rothenfusser S, Schubert B, Hilgendorff A, Hellmuth JC, Scherer C, Muenchhoff M, von Bergwelt-Baildon M, Stark K, Straub T, Brocker T, Keppler OT, Subklewe M, Krug AB.
Impaired function and delayed regeneration of dendritic cells in COVID-19.
PLOS Pathogens 2021; 17:e1009742.
JIF2020 6.2
https://pubmed.ncbi.nlm.nih.gov/34614036/
203. Schneider M, Heeb L, Beffinger M, Pantelyushin S, Linecker M, Roth L, Lehmann K, Ungethüm U, Kobold S.
Attenuation of peripheral serotonin inhibits tumor growth and enhances immune checkpoint blockade therapy in murine tumor models.
Science Translational Medicine 2021; 13:eabc8188.
JIF2020 16.3
https://www.science.org/doi/10.1126/scitranslmed.abc8188
203. Tokarew N, Gosalvez Suarez J, Nottebrock A, Briukhovetska D, Endres S, Cadilha B, Kobold S.
Flow cytometry detection and quantification of CAR T cells into solid tumors.
Methods in Cell Biology 2021;
JIF2020 1.4
https://www.sciencedirect.com/science/article/pii/S0091679X21000583?dgcid=author
202. Boehmer D, Formisano S, de Oliveira Mann C, Mueller S, Kluge M, Metzger P, Rohlfs M, Hörth Ch, Kocheise L, Lichtenthaler S, Hopfner KP, Endres S, Rothenfusser S, Friedel C, Duewell P, Schnurr* M, Koenig* L.
OAS1/RNase L executes RIG-I ligand-dependent tumor cell apoptosis.
Science Immunology 2021; 61, eabe2550.
JIF2021 30.6
https://immunology.sciencemag.org/content/6/61/eabe2550
https://www.lmu-klinikum.de/aktuelles/pressemitteilungen/programmierter-zelltod-von-tumorzellen-durch-synthetische-rna-molekule/3b1205f11defadda
201. Magg* Th, Okano* T, Koenig* L, Boehmer D, Schwartz S, Inoue K, Heimall J, Licciardi F, Ley-Zaporozhan J, Ferdman R, Park E, Calderon B, Dey D, Kanegane H, Cho K, Montin D, Reiter K, Griese M, Albert M, Rohlfs M, Gray P, Walz C, Conn G, Sullivan K, Klein Ch, Morio* T, Hauck* F.
Heterozygous OAS1 gain-of-function variants cause an autoinflammatory immunodeficiency.
Science Immunology 2021; 60, eabf9564.
JIF2021 30.6
https://immunology.sciencemag.org/content/6/60/eabf9564
*contributed equally
201. Di Pilato M*, Kfuri-Rubens R*, Pruessmann J*, Ozga AJ*, Messemaker M, Cadilha B, Sivakumar R, Cianciaruso Ch, Warner RD, Marangoni F, Carrizosa E, Lesch S, Billingsley J, Perez-Ramos D, Zavala F, Rheinbay E, Luster AD, Gerner MY, Kobold S, Pittet MJ, Mempel TR.
CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment.
Cell 2021, 184:4512-30.
JIF2020 41.6
https://www.sciencedirect.com/science/article/abs/pii/S0092867421008564?dgcid=coauthor
*contributed equally
201. Lesch S, Blumenberg V, Stoiber S, Gottschlich A, Ogonek J, Cadilha B, Dantes Z, Rataj F, Dorman K, Lutz J, Karches C, Heise C, Kurzay M, Larimer B, Grassmann S, Rapp M, Nottebrock A, Kruger S, Tokarew N, Metzger P, Hoerth Ch, Benmebarek MR, Dhoqina D, Gruenmeier R, Seifert M, Oener A, Umut Ö, . . . Rothenfusser S, Duewell P, Koenig L, Schnurr M, Subklewe M, Liss A, Halama N, Reichert M, Mempel T, Endres S, Kobold S.
T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours
Nature Biomedical Engineering 2021; 35:2243-2257.
JIF2020 20.0
https://www.nature.com/articles/s41551-021-00737-6
https://www.lmu-klinikum.de/aktuelles/pressemitteilungen/neue-strategie-gegen-bauchspeicheldrusenkrebs/f95d2c0d7ad55197
200. Linder A, Bothe V, Linder N, Schwarzlmüller P, Dahlström F, Bartenhagen Ch, Dugas M, Pandey D, Thorn-Seshold J, Boehmer D, König LM, Kobold S, Schnurr M, Rädler J, Spielmann G, Karimzadeh H, Schmidt A, Endres S, Rothenfusser S.
Defective interfering genomes and the full-length viral genome trigger RIG-I after infection with vesicular stomatitis virus in a replication dependent manner.
Frontiers in Immunology 2021; 12:595390.
JIF2020 6.4
http://journal.frontiersin.org/article/10.3389/fimmu.2021.595390/full?&utm_source=Email_to_authors_&utm_medium=Email&utm_content=T1_11.5e1_author&utm_campaign=Email_publication&field=&journalName=Frontiers_in_Immunology&id=595390
199. Blaeschke F, Stenger D, Apfelbeck A, Cadilha B, Benmebarek MR, Mahdawi J, Ortner E, Lepenies M, Habjan N, Rataj F, Willer S, Kaeuferle T, Majzner R, Busch D, Kobold S, Feuchtinger T.
Augmenting anti-CD19 and anti-CD22 CAR T-cell function using PD-1-CD28 checkpoint fusion proteins.
Blood Cancer Journal 2021; 11:108.
JIF2020 8.0
199. Brand I, Gilberg L, Bruger JM, Gari M, Wieser A, Eser TM, Frese J, Ahmed M, Rubio-Acero R, Guggenbuehl Noller JM, Casteletti N, Diekmannshemke J, Thiesbrummel S, Huynh D, Winter S, Fuchs Ch, Hoelscher M, Roider J, Kobold S, Pritsch M, Geldmacher Ch.
Broad T cell targeting of structural proteins after SARS-CoV-2 infection: High throughput assessment of T cell reactivity using an automated interferon gamma release assay.
Frontiers in Immunology 2021; 12:688436.
JIF2020 6.4
199. Sams L, Kruger S, Heinemann V, Bararia D, Haebe S, Alig S, Haas M, Zhang D, Westphalen CB, Ormanns S, Metzger P, Werner J, Weigert O, von Bergwelt‐Baildon M, Rataj F, Kobold S, Boeck S.
Alterations in regulatory T cells and immune checkpoint molecules in pancreatic cancer patients receiving FOLFIRINOX or gemcitabine plus nab‐paclitaxel.
Clinical and Translational Oncology 2021; 23:2394-2401.
JIF2020 2.8
199. Karaki S, Blanc C, Tran T, Galy-Fauroux I, Mougel A, Dransart E, Anson M, Tanchot C, Paolini L, Gruel N, Gibault L, Le Pimpec-Barthes F, Fabre E, Benhamouda N, Badoual C, Damotte D, Donnadieu E, Kobold S, Mami-Chouaib F, Golub R, Johannes L, Tartour E.
CXCR6-deficiency impairs cancer vaccine efficacy and CD8+resident memory T cell recruitment in head and neck and lung tumors.
Journal for Immunotherapy for Cancer 2021; 9:e001948.
JIF2020 10.3
https://cancerimmunolres.aacrjournals.org/content/7/2_Supplement/A172
199. Benmebarek MR, Cadilha B, Hermman M, Lesch S, Schmitt S, Stoiber S, Darwich A, Augsberger Ch, Brauchle B, Rohrbacher L, Oener A, Seifert M, Schwerdtfeger M, Gottschlich A, Rataj F, Fenn NC, Klein Ch, Subklewe M, Endres S, Hopfner KP, Kobold S.
A modular and controllable T cell therapy platform for acute myeloid leukemia.
Leukemia 2021; 35:2243-2257.
JIF2020 8.7
https://pubmed.ncbi.nlm.nih.gov/33414484/
198. Prokopi A, Tripp Ch, Tummers B, Hornsteiner F, Spoeck S, Crawford J, Clements D, Efremova M, Hutter K, Bellmann L, Cappellano G, Cadilha B, Kobold S, Boon L, Ortner D, Trajanoski Z, Chen S, de Gruijl T, Idoyaga J, Green D, Stoitzner P.
Skin dendritic cells in melanoma are key for successful checkpoint blockade therapy.
The Journal of Immunotherapy for Cancer 2021; 9:e000832.
JIF2019 10.3
https://pubmed.ncbi.nlm.nih.gov/33408092/
2020
198. Kuhlmann C, Schenck TL, Tluczynski K, Aszodi A, Metzger P, Giunta R, Wiggenhauser PS.
Experimental approach to nasal septal cartilage regeneration with adipose tissue-derived stem cells and decellularized porcine septal cartilage.
Xenotransplantation 2020; 1-11.
JIF2019 3.5
https://pubmed.ncbi.nlm.nih.gov/33350016/
198. Piseddu I, Röhrle N, Knott M, Moder S, Eiber S, Schnell K, Vetter V, Meyer B, Layritz P, Kühnemuth B, Wiedemann G, Grün J, Perleberg C, Rapp M, Endres S, Anz D.
Constitutive expression of CCL22 Is mediated by T cell-derived GM-CSF.
The Journal of Immunology 2020; 205:2056-2065.
JIF2019 4.3
https://pubmed.ncbi.nlm.nih.gov/32907996/
197. Segura-Bayona S, Villamor-Paya M, Attolini C, Koenig LM, Sanchiz-Calvo M, Boulton SJ, Stracker TH.
Tousled-like kinases suppress innate immune signaling triggered by alternative lengthening of telomeres.
Cell Reports 2020; 32:107983
JIF2019 7.7
https://pubmed.ncbi.nlm.nih.gov/32755577/
197. Boehmer D, Koehler L, Magg T, Metzger P, Rohlfs M, Ahlfeld J, Rack-Hoch A, Reiter K, Albert M, Endres S, Rothenfusser S, Klein Ch, Koenig L, Hauck F.
A novel complete autosomal recessive STAT1 LOF variant causes immunodeficiency with hemophagocytic lymphohistiocytosis-like hyperinflammation.
The Journal of Allergy and Clinical Immunology 2020; 8:3102-3111.
JIF2019 10.3
https://pubmed.ncbi.nlm.nih.gov/32603902/
196. Geiger M, Stubenrauch KG, Sam J, Richter W, Jordan G, Eckmann J, Hage C, Gonzalez-Nicolini V,
Freimoser-Grundschober A, Ritter M, Lauer M, Stahlberg H, Ringler P, Patel J, Sullivan E, Grau-Richards S, Endres S, Kobold S, Umaña P, Brünker P, Klein Ch.
Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody.
Nature Communications 2020; 11:3196. Featured in Editors‘ Highlights “Translational and clinical research”
JIF2019 12.1
https://pubmed.ncbi.nlm.nih.gov/32581215/
195. Metzger P, Kirchleitner S, Boehmer D, Hörth Ch, Eisele A, Ormanns S, Gunzer M, Lech M, Lauber K, Endres S, Duewell P, Schnurr M, König L.
Systemic but not MDSC-specific IRF4 deficiency promotes an immunosuppressed tumor microenvironment in a murine pancreatic cancer model.
Cancer Immunology, Immunotherapy 2020; 69:2101-2112.
JIF2019 4.9
https://pubmed.ncbi.nlm.nih.gov/32448983/
195. Stenger D, Stief T, Kaeuferle T, Willier S, Rataj F, Schober K, Binje V, Lotfi R, Wagner B, Grünewald T, Kobold S, Busch D, Jeremias I, Blaeschka F, Feuchtinger T.
Endogenous TCR promotes in vivo persistence of CD19-CAR-T cells compared to a CRISPR/Cas9-mediated TCR knockout CAR.
Blood 2020; 136:1407-1418.
JIF2019 10.7
https://pubmed.ncbi.nlm.nih.gov/32483603/
195. Huber J*, Ahlfeld J*, Scheck M, Zaucha M, Witter K, Lehmann L, Karimzadeh H, Pritsch M, Hölscher M, von Sonnenburg F, Dick A, Barba-Spaeth G, Krug A, Rothenfußer S*, Baumjohann D* .
Dynamic changes in circulating T follicular helper cell composition predict neutralizing antibody responses after yellow fever vaccination.
Clinical & Translational Immunology 2020; 9:e1129.
* equally contributed
JIF2019 6.5
https://pubmed.ncbi.nlm.nih.gov/32419947/
194. Ruzicka M, König L, Formisano S, Boehmer D, Vick B, Heuer EM, Meinl H, Kocheise L, Zeitlhoefler M, Ahlfeld J, Kobold S, Endres S, Subklewe M, Duewell P, Schnurr M, Jeremias I, Lichtenegger F, Rothenfusser S.
RIG-I-based immunotherapy enhances survival in preclinical AML models and sensitizes AML cells to checkpoint blockade.
Leukemia 2020; 34:1017-1026.
JIF2019 9.9
https://www.ncbi.nlm.nih.gov/pubmed/31740809
2019
193. Metzger P, Kirchleitner S, Kluge M, Koenig L, Hoerth Ch, Rambuscheck CA, Boehmer D, Ahlfeld J, Kobold S, Friedel C, Endres S, Schnurr M, Duewell P.
Immunostimulatory RNA leads to functional reprogramming of myeloid-derived suppressor cells in pancreatic cancer.
Journal for Immunotherapy of Cancer 2019; 7:288.
JIF2019 8.7
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836385/
193. Scherm M, Serr I, Zahm A, Schug J, Bellusci S, Manfredini R,Salb V, Gerlach K, Weigmann B, Ziegler AG, Kästner KH, Daniel C.
miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes.
Nature Communications 2019; 10:5697.
JIF2019 12.1
193. Scherm M, Serr I, Kästner KH, Daniel C.
The role of T cell miRNAs for regulatory T cell induction in islet autoimmunity.
Molecular Metabolism 2019; 27S:S122-S128.
JIF2019 6.5
193. Becker M, Serr I, Salb V, Ott V, Mengel L, Blüher M, Weigmann B, Hauner H, Tschöp M, Daniel C.
Short-term cold exposure supports human Treg induction in vivo.
Molecular Metabolism 2019; 28:73-82.
JIF2019 6.5
193. Lorenz G, Moschovaki-Filippidou F, Würf V, Metzger P, Steiger S, Batz F, Carbajo-Lozoya J, Koziel J, Schnurr M, Cohen CD, Schmaderer Ch, Anders HJ, Lindenmeyer M, Lech M*.
IFN regulatory factor 4 controls post-ischemic inflammation and prevents chronic kidney disease.
Frontiers in Immunology 2019; 10:2162.
JIF2019 5.1
192. Schewe J, Makeschin MC, Liss I, Mayr D, Zhang J, Khandoga A, Rothenfußer S, Schnurr M, Gerbes AL, Steib CJ.
Ischemic postconditioning (IPostC) protects fibrotic and cirrhotic rat livers after warm ischemia.
Canadian Journal of Gastroenterology and Hepatology 2019; 2019:5683479.
JIF2019 2.1
192. Helms M, Jahn-Hofmann K, Gnerlich F, Metz-Weidmann Ch, Braun M, Dietert G, Scherer P, Grandien K, Theilhaber J, Cao H, Wagenaar T, Schnurr M, Endres S, Wiederschain D, Scheidler S, Rothenfusser S, Brunner B, Koenig L.
Utility of the RIG-I agonist triphosphate RNA for melanoma therapy.
Molecular Cancer Therapeutics 2019; 18:2343-2356.
JIF2019 5.6
https://www.ncbi.nlm.nih.gov/pubmed/31515294
191. Mountford SA, Ringleb A, Schwaiger R, Mayr D, Kobold S, Dinarello Ch, Bufler P.
Interleukin-37 inhibits colon carcinogenesis during chronic colitis.
Frontiers in Immunology 2019; 10:2632.
JIF2019 5.1
191. Brown P, Tan AC, El-Esawi MA, Liehr T, Blanck O, Gladue DP, ...Kobold S, ..., Veys R, Zhou YQ.
Large expert-curated database for benchmarking document similarity detection in biomedical literature search.
Database 2019; doi: 10.1093.
JIF2019 2.6
191. Küpper C, Heinrich J, Kamm K, Bücklein V, Rothenfusser S, Straube A.
Pembrolizumab for progressive multifocal leukoencephalopathy due to primary immunodeficiency.
Neurology Neuroimmunology & Neuroinflammation 2019; 6:e628.
JIF2019 7.7
191. Darowski D, Jost Ch, Stubenrauch K, Wessels U, Benz J, Ehler A, Freimoser-Grundschober A, Brünker P, Mössner E, Umana P, Kobold S, Klein Ch.
P329G-CAR-J: a novel Jurkat-NFAT-based CAR-T reporter system recognizing the P329G Fc mutation.
Protein Engineering, Design and Selection 2019; 32:207-218.
JIF2019 1.9
191. Wiedemann G, Röhrle N, Makeschin MC, Fesseler J, Endres S, Mayer D, Anz D.
Peritumoral CCL1 and CCL2 expressing cells in hepatocellular carcinomas shape the tumor immune infiltrate.
Pathology 2019; 51:586-592.
JIF2019 3.8
https://www.ncbi.nlm.nih.gov/pubmed/31445808
190. Karches C, Benmebarek MR, Schmidbauer M, Kurzay M, Klaus R, Geiger M, Rataj F, Cadilha B, Lesch S, Heise C, Murr R, vom Berg J, Jastroch M, Lamp D, Ding J, Duewell P, Niederfellner G, Sustmann C, Endres S, Klein Ch, Kobold S.
Bispecific antibodies enable synthetic agonistic receptor-transduced T cells for tumor immunotherapy.
Clinical Cancer Research 2019; 25:5890-5900.
JIF2019 10.1
https://www.ncbi.nlm.nih.gov/pubmed/31285373
189. Rapp M, Wintergerst M, Kunz W, Vetter V, Knott M, Lisowski D, Haubner S, Moder S, Thaler R, Eiber S, Meyer B, Röhrle N, Piseddu I, Grassmann S, Layritz P, Kühnemuth B, Stutte S, Bourquin C, von Andrian U, Endres S*, Anz D. (*corresponding author)
CCL22 controls immunity by promoting regulatory T cell communication with dendritic cells in lymph nodes.
Journal of Experimental Medicine 2019; 116:5514-5522.
JIF2019 11.7
https://www.ncbi.nlm.nih.gov/pubmed/3091079
188. Liu X, Li J, Cadilha B, Markota A, Voigt C, Huang Z, Lin P, Wang D, Juncheng D, Kranz G, Krandick A, Libl D, Zitzelsberger H, Zagorski I, Braselmann H, Pan M, Zhu S, Huang Y, Niedermeyer S, Reichel Ch, Uhl B, Briukhovetska D, Suarez Gosalvez J, Kobold S, Gires O, Wang H.
Epithelial-type systemic breast carcinoma cells with a restricted mesenchymal transition are a major source of metastasis.
Science Advances 2019; 5:eaav4275.
JIF2019 13.1
188. Eisenmesser EZ, Gottschlich A, Redzic JS, Paukovich N, Nix JC, Azam T, Zhang L, Zhao R, Kieft JS, The E, Meng X, Dinarello CA.
Interleukin-37 monomer is the active form for reducing innate immunity.
Proceedings of the National Academy of Sciences 2019; 116:5514-5522.
JIF2019 9.4
https://www.ncbi.nlm.nih.gov/pubmed/30429531
188. Rataj F, Jacobi S, Stoiber S, Asang F, Ogonek J, Tokarew N, Cadilha B, van Puijenbroek E, Heise C, Duewell P, Endres S, Klein Ch, Kobold S.
High affinity CD16-polymorphism and Fc-engineered antibodies enable activity of CD16-chimeric antigen receptor-modified T cells for cancer therapy.
British Journal of Cancer 2019; 120:79-87.
JIF2019 5.8
https://www.ncbi.nlm.nih.gov/pubmed/30429531
187. Wiedemann G, Aithal C, Kraechan A, Heise C, Cadilha B, Zhang J, Duewell P, Ballotti R, Endres S, Bertolotto C, Kobold S.
Microphthalmia-associated transcription factor (MITF) regulates immune cell migration into melanoma.
Translational Oncology 2019; 12:350-360.
JIF2019 3.6
186. Ardelt MA, Fröhlich T, Martini E, Müller M, Kanitz V, Atzberger C, Cantonati P, Meßner M, Posselt L, Lehr T, Wojtyniak JG, Ulrich M, Arnold GJ, König L, Parazzoli D, Zahler S, Rothenfußer S, Mayr D, Gerbes A, Scita G, Vollmar AM, Pachmayr J.
Inhibition of cyclin-dependent kinase 5 - a novel strategy to improve sorafenib response in HCC therapy.
Hepatology 2018; 69:376-393.
JIF2019 14.7
2018
186. Karsten MM, Enders S, Knabl J, Kirn V, Duewell P, Rack B, Blohmer JU, Mayr D, Dian D.
Biologic meshes and synthetic meshes in cancer patients: a double-edged sword: differences in production of IL-6 and IL-12 caused by acellular dermal matrices in human immune cells.
Archives Gynecology Obstetrics 2018; 297:1265-1270.
JIF2018 2.2
186. Kuehnemuth B, Piseddu I, Wiedemann G, Lauseker M, Kuhn Ch, Hofmann S, Schmoeckel E, Endres S, Mayr D, Jeschke U, Anz D.
CCL1 is a major regulatory T cell attracting factor in human breast cancer.
BMC Cancer 2018; 18:1278.
JIF2018 2.9
185. Weidenbusch M, Song S, Iwakura T, Shi C, Rodler S, Kobold S, Mulay SR, Honarpisheh MM, Anders HJ.
IL-22 sustains epithelial integrity in progressive kidney remodeling and fibrosis.
Physiological Reports 2018; 6:e13817.
JIF2018 1.3
185. Herrmann M, Krupka C, Deiser K, Brauchle B, Marcinek A, Ogrinc Wagner A, Rataj F, Mocikat R, Metzeler KH, Spiekermann K, Kobold S, Fenn NC, Hopfner KP, Subklewe M.
Bifunctional PD-1 x αCD3 x αCD33 fusion protein reverses adaptive immune escape in acute myeloid leukemia.
Blood 2018; 32:2484-2494.
JIF2018 15.1
185. Rataj F, Kraus F, Chaloupka M, Grassmann S, Heise C, Cadilha B, Duewell P, Endres S, Kobold S.
PD1-CD28 fusion protein enables CD4+ T cell help for adoptive T cell therapy in models of pancreatic cancer and non-Hodgkin-lymphoma.
Frontiers in Immunology 2018; 9:1955.
JIF2018 4.7
https://www.frontiersin.org/articles/10.3389/fimmu.2018.01955/full
184. Metzger P, Kirchleitner S, König L, Hörth Ch, Kobold S, Endres S, Schnurr M, Duewell P.
Dying cells expose a nuclear antigen cross-reacting with anti-PD-1 monoclonal antibodies.
Science Reports 2018; 8:8810.
JIF2018 4.1
183. Andrade L, Tay R, Pan D, Luoma A, Ito Y, Badrinath S, Tsoucas D, Franz B, May K, Harvey Ch, Kobold S, Pyrdol J, Yoon Ch, Yuan G, Hodi S, Dranoff G, Wucherpfennig K.
Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell–driven tumor immunity.
Science 2018; 359:1537-1542.
JIF2018 41.1
https://www.ncbi.nlm.nih.gov/pubmed/29599246
183. Makanyengo R, Duewell P, Reichl C, Hörth Ch, Lehr HA, Fischer S, Clavel T, Denk G, Hohenester S, Kobold S, Endres S, Schnurr M, Bauer Ch.
Nlrp3-dependent IL-1β inhibits CD103+ dendritic cell differentiation in the gut.
JCI Insight 2018; 8;3(5).
JIF2018 6,0
182. Christ A, Günther P, Lauterbach MAR, Duewell P, Biswas D, Pelka K, Scholz CJ, Oosting M, Haendler K, Baßler K, Klee K, Schulte-Schrepping J, Ulas T, Moorlag SJCFM, Kumar V, Park MH, Joosten LAB, Groh LA, Riksen NP, Espevik T, Schlitzer A, Li Y, Fitzgerald ML, Netea MG, Schultze JL, Latz E.
Western diet triggers NLRP3-dependent innate immune reprogramming.
Cell 2018; 172:162-175.
JIF2018 31.4
https://www.ncbi.nlm.nih.gov/pubmed/29328911
182. Einer C, Hohenester S, Wimmer R, Wottke L, Artmann R, Schulz S, Gosmann C, Simmons A, Leitzinger C, Eberhagen C, Borchard S, Schmitt S, Hauck SM, von Toerne C, Jastroch M, Walheim E, Rust C, Gerbes AL, Popper B, Mayr D, Schnurr M, Vollmar AM, Denk G, Zischka H.
Mitochondrial adaptation in steatotic mice.
Mitochondrion 2017; 40:1-12
JIF2018 3.7
2017
182. Damby D, Horwell C, Baxter P, Kueppers U, Schnurr M, Dingwell D, Duewell P.
Volcanic ash activates the NLRP3 inflammasome in murine and human macrophages.
Frontiers in Immunology 2017; 8:2000
JIF2018 6.4
https://www.ncbi.nlm.nih.gov/pubmed/29403480
182. Voigt C*, May P*, Gottschlich A*, Markota A, Wenk D, Gerlach I, Voigt S, Stathopoulos GT, Arendt K, Heise C, Rataj F, Janssen KP, Königshoff M, Winter H, Himsl I, Thasler W, Schnurr M, Rothenfußer S, Endres S, Kobold S.
Cancer cells induce interleukin-22 production from memory CD4+ T cells via interleukin-1 to promote tumor growth.
Proceedings of the National Academy of Sciences 2017; 10:1073
JIF 9.6
https://www.ncbi.nlm.nih.gov/pubmed/?term=voigt+c+may+p
* contributed equally to this study
181. Zwicker S, Hattinger E, Bureik D, Batycka-Baran A, Schmidt A, Gerber PA, Rothenfusser S, Gilliet M, Ruzicka T, Wolf R.
Th17 micro-milieu regulates NLPR1-dependent caspase-5 activity in skin autoinflammation.
PLoS One 2017; 12:e0175153
JIF 3.5
181. Einer C, Hohenester S, Wimmer R, Wottke L, Artmann R, Schulz S, Gosmann C, Simmons A, Leitzinger C, Eberhagen C, Borchard S, Schmitt S, Hauck SM, von Toerne C, Jastroch M, Walheim E, Rust C, Gerbes AL, Popper B, Mayr D, Schnurr M, Vollmar AM, Denk G, Zischka H.
Data on chow, liver tissue and mitochondrial fatty acid compositions as well as mitochondrial proteome changes after feeding mice a western diet for 6-24 weeks.
Data Brief 2017; 15:163-169
181. Ahlfeld J, Filser S, Schmidt F, Wefers AK, Merk DJ, Glaß R, Herms J, Schüller U
Neurogenesis from Sox2 expressing cells in the adult cerebellar cortex.
Scientific Report - Nature 2017; 7:6137
JIF 4.3
181. Wennhold K, Thelen M, Haustein N, Reuter S, Rataj F, Kobold S, Garcia-Marquez M, Schlösser H, Chakupurakal G, Theurich S, Hallek M, Shimabukuro-Vornhagen A, von Bergwelt-Baildon M.
Using Antigen-Specific B Cells to Combine Antibody and T Cell-Based Cancer Immunotherapy.
Cancer Immunology Research 2017; 5:730-743
JIF 8.3
2016
181. Freier CP, Kuhn C, Endres S, Mayr D, Freise K, Jeschke U, Anz D.
FOXP3+ cells recruited by CCL22 into breast cancer correlates with less tumor nodal infiltration.
Anticancer Research 2016; 36:3139-45.
JIF 1.9
180. Matheis F, Heppt MV, Graf SA, Düwell P, Kammerbauer C, Aigner A, Besch R, Berking C.
A Bifunctional Approach of Immunostimulation and uPAR Inhibition Shows Potent Antitumor Activity in Melanoma.
Journal of Investigative Dermatology 2016, 136:2475-2484
JIF 6,3
180. Tufman A, Huber RM, Völk S, Aigner F, Edelmann M, Gamarra F, Kiefl R, Kahnert K, Tian F, Boulesteix AL, Endres S, Kobold S.
Interleukin-22 is elevated in lavage from patients with lung cancer and other pulmonary diseases.
BMC Cancer 2016; 16:409.
JIF 3.8
179. Wiedemann G, Jacobi S, Chaloupka M, Hamm S, Strobl S, Baumgartner R, Rothenfusser S, Duewell P, Endres S, Kobold S.
A novel TLR7 agonist reverses NK cell anergy and cures lymphoma-bearing mice.
Oncoimmunology 2016; 5:e1189051.
JIF 6.3
178. Wiedemann G, Knott M, Vetter V, Rapp M, Haubner S, Fesseler J, Kühnemuth B, Layritz P,
Thaler R, Kruger S, Ormanns S, Mayr D, Endres S, Anz D.
Cancer cell-derived IL-1α induces CCL22 and the recruitment of regulatory T cells.
Oncoimmunology 2016; 5:e1175794.
JIF 6.3
177. Hotz C, Treinis M, Mottas I, Rötzer L, Oberson A, Spagnuolo L, Perdicchio M, Spinetti T, Herbst T, Bourquin C.
Reprogramming of TLR7 signaling enhances antitumor NK and cytotoxic T cell responses.
Oncoimmunology 2016; 5:e1232219
JIF 7.7
177. Roskopf CC, Braciak TA, Fenn NC, Kobold S, Fey GH, Hopfner KP, Oduncu FS.
Dual-targeting triplebody 33-3-19 mediates selective lysis of biphenotypic CD19+ CD33+ leukemia cells.
Oncotarget 2016; 7:22579-89.
JIF 6.6
177. Pritsch M, Ben-Khaled N, Chaloupka M, Kobold S, Berens-Riha N, Peter A, Liegl G, Schubert S, Hölscher M, Löscher T, Wieser A.
Comparison of intranasal outer membrane vesicles with cholera toxin and injected MF59C.1 as adjuvants for malaria transmission blocking antigens AnAPN1 and Pfs48/45.
Journal of Immunology Research 2016; 2016:3576028.
JIF 2.9
177. Castoldi R, Schanzer J, Panke C, Jucknischke U, Neubert N, Croasdale R, Klein C,
Scheuer W, Niederfellner G, Auer J, Kobold S, Sustmann C.
TetraMabs: Simultaneous targeting of four oncogenic receptor tyrosine kinases for tumor growth inhibition in heterogeneous tumor cell populations.
Protein Engineering Design and Selection 2016; 29:467-75.
JIF 2.5
177. Heidegger S, Gößl D, Schmidt A, Niedermayer S, Argyo Ch, Endres S, Bein T, Bourquin C.
Immune response to functionalized mesoporous silica nanoparticles for targeted drug delivery.
Nanoscale 2016; 8:938-48.
JIF 7.4
2015
176. Heidegger S, Jarosch A, Schmickl M, Endres S, Bourquin C, Hotz C.
Mycoplasma hyorhinis-contaminated cell lines activate primary innate immune cells via a protease-sensitive factor.
PLOS ONE 2015; 10:e0142523.
JIF 3.7
175. Rapp M, Grassmann S, Chaloupka M, Layritz P, Kruger S, Ormanns S, Rataj F, Janssen KP, Endres S, Anz D, Kobold S.
C-C chemokine receptor type-4 transduction of T cells enhances interaction with dendritic cells, tumor infiltration and therapeutic efficacy of adoptive T cell transfer.
Oncoimmunology 2015; 5:e1105428.
JIF 6.3
174. Lichtenegger F, Kondla I, Krempasky M, Weber A, Herold T, Krupka C, Spiekermann K.
RNA and protein expression of herpesvirus entry mediator (HVEM) is associated with molecular markers, immunity-related pathways and relapse-free survival of patients with AML.
Cancer Immunology Immunotherapy 2015; 64:1505-15.
JIF 4.0
174. Anz D, Rapp M, Eiber S, Koelzer V, Thaler R, Haubner S, Knott M, Nagel S, Golic M, Wiedemann G, Bauernfeind F, Wurzenberger C, Hornung V, Scholz C, Mayr D, Rothenfusser S, Endres S, Bourquin C.
Suppression of intratumoral CCL22 by type I interferon inhibits migration of regulatory T cells and blocks cancer progression.
Cancer Research 2015; 75:4483-93.
JIF 9.3
173. Häcker G, Senft D, Weber A, Saathoff F, Berking C, Heppt M, Kammerbauer C, Rothenfusser S, Kellner S, Kurgys Z, Besch R.
In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-XL and Mcl-1 but in the absence of active BH3-only proteins.
Cell Death and Disease 2015; 6:e1996.
JIF 5.0
173. Hotz C, Roetzer L, Huber T, Sailer A, Oberson A, Treinies M, Heidegger S, Herbst T, Endres S, Bourquin C.
TLR and RLR signaling are reprogrammed in opposite directions after detection of viral infection.
The Journal of Immunology 2015; 195:4387-95.
JIF 5.4
172. Schnarfell F, Lichtenegger F, Emmerig K, Schlueter M, Neitz J, Draenert R, Hiddemann W, Subklewe M.
T cells are functionally not impaired in AML: increased PD-1 expression is only seen at time of relapse and correlates with a shift towards the memory T cell compartment.
Journal of Haematology and Oncology 2015; 8:93.
JIF 4.9
172. Kobold* S, Grassmann* S, Chaloupka M, Lampert C, Wenk S, Kraus F, Rapp M, Duewell P, Zeng Y, Schmollinger J, Schnurr M, Endres S#, Rothenfußer S#.
Impact of a new fusion receptor on PD-1-mediated immunosuppression in adoptive T cell therapy.
The Journal of the National Cancer Institute 2015; 107.
* contributed equally to this study, # share senior authorship
JIF 15.2
http://www.ncbi.nlm.nih.gov/pubmed/26105028
171. Freier C, Kuhn C, Rapp M, Endres S, Mayr D, Friese K, Anz D, Jeschke U.
Expression of CCL22 and infiltration by regulatory T-cells are increased in the decidua of human miscarriage placentas.
American Journal of Reproductive Immunology 2015; 74:216-27.
JIF 2.7
170. Duewell P, Beller E, Kirchleitner S, Adunka T, Bourhis H, Siveke J, Mayr D, Kobold S, Endres S, Schnurr M.
Targeted activation of melanoma differentiation-associated protein 5 (MDA5) for immunotherapy of pancreatic carcinoma.
OncoImmunology 2015; 4:e1029698.
JIF 6.3
169. Bauer C, Hees C, Sterzik A, Bauernfeind F, Mak´Anyengo R, Duewell P, Lehr HA, Noessner E, Wank R, Trauzold A, Endres S, Dauer M, Schnurr M.
Pro- and anti-apoptotic proteins of the Bcl-2 family regulate sensitivity of pancreatic cancer cells towards gemcitabine and T cell-mediated cytotoxicity.
Journal of Immunotherapy 2015; 38:116-26.
JIF 3.4
168. Kocabey S, Meinl H, MacPherson IS, Cassinelli V, Manetto A, Rothenfusser S, Liedl T, Lichtenegger FS.
Cellular uptake of Tile-assembled DNA nanotubes.
Journal of Nanomaterials 2015; 47-60.
JIF 2.4
168. Hoffmann F, Schmidt A, Dittmann Chevillotte M, Wisskirchen C, Hellmuth JC, Willms S, Gilmore RH, Glas J, Folwaczny M, Müller T, Berg T, Spengler U, Fitzmaurice K, Kelleher D, Reisch N, Rice CM, Endres S, Rothenfusser S.
Polymorphisms in MDA-5 link protein function to clearance of hepatitis C virus.
Hepatology 2015; 61:460-70.
JIF 10.4
2014
167. Kobold S, Steffen J, Chaloupka M, Grassmann S, Henkel J, Castoldi R, Zeng Y, Chmielewski M, Schmollinger J, Schnurr M, Rothenfußer S, Schendel DJ, Abken H, Sustmann C, Niederfellner CG, Klein C, Bourquin C, Endres S.
Selective bispecific T cell recruiting antibody enhances anti-tumor activity of adoptive T cell transfer.
The Journal of the National Cancer Institute 2014; 107:364.
JIF 15.2
166. Duewell P, Steger A, Lohr H, Bourhis H, Hoelz H, Kirchleitner SV, Stieg MR, Grassmann S, Kobold S, Siveke JT, Endres S, Schnurr M.
RIG-I-like helicases induce immunogenic cell death of pancreatic cancer and sensitize tumors killing by CD8+ T-cells.
Cell Death and Differentiation 2014; 21:1825-37.
JIF 8.4
165. Hermans C, Anz D, Engel J, Kirchner T, Endres S, Mayr D.
Analysis of FoxP3+ T-regulatory cells and CD8+ T-cells in ovarian carcinoma: location and tumor infiltration patterns are key prognostic markers.
PLOS One 2014; 9:e111757
JIF 2.8
165. Roskopf CC, Schiller C, Braciak TA, Kobold S, Schubert A, Fey GH, Hopfner KP, Oduncu F.
T cell-recruiting triplebody 19-3-19 mediates serial lysis of malignant B-lymphoid cells by a single T cell.
Oncotarget 2014; 5:6466-83.
JIF 6.6
165. Luetkens T, Kobold S, Cao Y, Ristic M, Schilling G, Tams S, Bartels BM, Templin J, Bartels K, Hildebrandt Y, Yousef S, Marx A, Haag F, Bokemeyer C, Kröger N, Atanackovic D.
Functional autoantibodies against SSX-2 and NY-ESO-1 in multiple myeloma patients after allogeneic stem cell transplantation.
Cancer Immunology Immunotherapy 2014; 63:1151-62.
JIF 3.6
165. Wilson NS, Duewell P, Yang B, Li Y, Marsters S, Koernig S, Latz E, Maraskovsky E, Morelli AB, Schnurr M, Ashkenazi A.
Inflammasome-dependent and -independent IL-18 production mediates immunity to the ISCOMATRIX adjuvant.
The Journal of Immunology 2014; 192:3259-68.
JIF 5.5
165. Krupka C, Kufer P, Kischel R, Zugmaier G, Bögeholz J, Köhnke T, Lichtenegger FS, Schneider S, Metzeler KH, Fiegl M, Spiekermann K, Baeuerle PA, Hiddemann W, Riethmüller G, Subklewe M.
CD33 target validation and sustained depletion of AML blasts in long-term cultures by the bispecific T-cell-engaging antibody AMG 330.
Blood 2014; 123:356-65.
JIF 9.9
165. Bauer C, Sterzik A, Bauernfeind F, Duewell P, Conrad C, Kiefl R, Endres S, Eigler A, Schnurr M, Dauer M.
Concomitant gemcitabine therapy negatively affects DC vaccine-induced CD8+ T-cell and B-cell responses but improves clinical efficacy in an murine pancreatic carcinoma model.
Cancer Immunology Immuntherapy 2014; 63:321-33.
JIF 3.6
164. Kim S, Kaiser V, Beier E, Bechheim M, Guenthner-Biller M, Ablasser A, Berger M, Endres S, Hartmann G, Hornung V.
Self-priming determines high type I IFN production by plasmacytoid dendritic cells.
European Journal of Immunology 2014; 44:807-18.
JIF 5.0
163. Kulkarni P. O*, Hartter I*, Mulay R. S*, Hagemann J, Darisipudi N. M, Kumar S, Romoli S, Thomasova D, Ryu M, Kobold S, Anders HJ.
TLR4-induced IL-22 release accelerates kidney regeneration.
Journal of the American Society of Nephrology 2014; 25:978-89.
JIF 9.0 *diese Autoren leisteten gleichwertigen Beitrag
163. Anz D, Kruger S, Haubner S, Rapp M, Bourquin C, Endres S.
The dipeptidylpeptidase-IV inhibitors sitagliptin, vildagliptin and saxagliptin do not impair innate and adaptive immune responses.
Diabetes, Obesity and Metabolism 2014; 16:569-72.
JIF 5.2
162. Kobold S, Merk M, Hofer L, Peters P, Bucala R, Endres S.
The macrophage migration inhibitory factor (MIF)-homologue D-dopachrome tautomerase is a therapeutic target in a murine melanoma model.
Oncotarget 2014; 5:103-7.
JIF 6.6
2013
161. Heidegger S*, Anz D*, Stephan N, Bohn B, Herbst T, Fendler WP, Suhartha N, Sandholzer N, Kobold S, Hotz C, Eisenaecher K, Radtke-Schuller S, Endres S, Bourquin C.
Virus-associated activation of innate immunity induces rapid disruption of Peyer’s patches in mice.
Blood 2013; 122:2591-9.
JIF 9.1 *diese Autoren leisteten gleichwertigen Beitrag
160. Kobold S, Völk S, Clauditz T, Küpper NJ, Minner S, Tufmann A, Düwell P, Lindner M, Koch I, Heidegger S, Merk M, Rothenfußer S, Schnurr M, Huber RM, Sauter G, Wilczak W, Endres S.
Interleukin-22 is frequently in lung cancer and may contribute to tumor progression in chemotherapy-resistant disease.
Journal of Thoracic Oncology 2013; 8:1032-1042.
JIF 4.5
159. Castoldi R, Ecker V, Wiehle L, Majety M, Busl-Schuller R, Asmussen M, Nopora A, Jucknischke U, Osl F, Kobold S, Scheuer W, Venturi M, Klein C, Niederfellner G, Sustmann C.
A novel bispecific EGFR/Met antibody blocks tumor promoting phenotypic effects induced by resistance to EGFR inhibition and has potent anti-tumor activity.
Oncogene 2013; 32:5593-601.
JIF 7.4
159. Hohenauer T, Berking C, Schmidt A, Haferkamp S, Senft D, Kammerbauer C, Fraschka S, Graf SA, Irmler M, Beckers J, Flaig M, Aigner A, Höbel S, Hoffmann F, Hermeking H, Rothenfusser S, Endres S, Ruzicka T, Besch R.
The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival.
EMBO Molecular Medicine 2013; 5:919-34.
JIF 7.8
158. Heidegger S, Kirchner SK, Stephan N, Bohn B, Suhartha N, Hotz C, Anz D, Sandholzer N, Stecher B, Rüssmann H, Endres S, Bourquin C.
TLR activation excludes circulating naive CD8+ T cells from gut-associated lymphoid organs in mice.
Journal of Immunology 2013; 190:5313-20.
JIF 5.5
157. Schmidt K, Zilio S, Schmollinger JC, Bronte V, Blankenstein T, Willimsky G.
Differently immunogenic cancers in mice induce immature myeloid cells that suppress.
CTL in vitro but not in vivo following transfer.
Blood 2013; 121:1740-8.
JIF 9.1
157. Ellermeier J, Wei J, Düwell P, Hoves S, Stieg M, Adunka T, Nörenberg D, Anders HJ, Mayr D,
Pöck H, Hartmann G, Endres S, Schnurr M.
Therapeutic efficacy of bifunctional siRNA combining TGF-β1 silencing with RIG-I activation in pancreatic cancer.
Cancer Research 2013; 73:1709-20.
JIF 8.7
156. Rieder F, Siegmund B, Bundschuh DS, Lehr HA, Endres S, Eigler A.
The selective phosphodiesterase 4 inhibitor roflumilast and phosphodiesterase 3/4 inhibitor pumafentrine reduce clincial score and TNF expression in experimental colitis in mice.
PLoS One 2013; 8:56867.
JIF 3.7
2012
155. Merk M, Mitchell R, Endres S, Bucala R.
D-dopachrome tautomerase (D-DT or MIF-2): Doubling the MIF cytokine family.
Cytokine 2012; 59:10-7.
JIF 3.5
154. Kobold S, Luetkens T, Bartels BM, Cao Y, Hildebrandt Y, Sezer O, Reinhard H, Templin J, Bartels K, Lajmi N, Haag F, Bokemeyer C, Kröger N, Atanackovic D.
Longitudinal analysis of tetanus- and influenza-specific IgG antibodies in myeloma patients.
Clinical and Developmental Immunology 2012; 2012:134081.
JIF 1.8
154. Vollbrecht T, Stirner R, Tufman A, Roider J, Huber RM, Bogner JR, Lechner A, Bourquin C,
Draenert R. Chronic progressive HIV-1 infection is associated with elevated levels of myeloid-derived suppressor cells.
AIDS 2012; 26:F31-7.
JIF 6.4
154. Bauer C, Duewell P, Lehr HA, Endres S, Schnurr M.
Protective and aggravating effects of Nlrp3 inflammasome activation in IBD Models: influence of genetic and environmental factors.
Digestive Diseases 2012; 1:82-90.
JIF 2.7
153. Wenzel M, Wunderlich M, Besch R, Poeck H, Willms S, Schwantes A, Kremer M, Sutter G, Endres S, Schmidt A, Rothenfusser S.
Cytosolic DNA triggers mitochondrial apoptosis via DNA-damage signalling proteins independently of AIM2 and RNA polymerase III.
Journal of Immunology 2012; 188:394-403.
JIF 5.5
152. Dann A, Poeck H, Croxford A, Gaupp S, Kierdorf K, Knust M, Pfeifer D, Maihoefer C, Endres S,
Kalinke U, Meuth S, Wiendl H, Knobeloch KP, Akira S, Waisman A, Hartmann G, Prinz M.
Cytosolic RIG-like-helicases act as negative regulators of sterile inflammation in the CNS.
Nature Neuroscience 2012; 15:98-106.
JIF 15.3
2011
151. Schueller V, Heidegger S, Sandholzer N, Suhartha N, Nickels P, Endres S, Bourquin C, Liedl T.
Cellular immunostimulation by CpG-sequence-coated DNA origami structures.
American Chemical Society ACS Nano 2011; 5:9696-702.
JIF 12.1
150. Kobold S, Isernhagen J, Hübel K, Kilic N, Bogner C, Frickhofen N, Bokemeyer C, Fiedler W.
Plerixafor is effective and safe for stem cell mobilization in heavily pretreated germ cell tumor patients.
Bone Marrow Transplantation 2011; 46:1053-6.
JIF 3.5
150. Lech M, Kantner C, Kulkarni O, Ryu M, Vlasova E, Heesemann J, Anz D, Endres S, Martin J, Koichi S, Kobayashi K, Flavell RA, Anders HJ.
Interleukin-1 receptor-associated kinase-M suppresses systemic lupus erythematosus.
Annals of the Rheumatic Diseases 2011; 70:2207-17.
JIF 9.1
149. Merk M, Zierow S, Leng L, Das R, Du X, Schulte W, Fan J, Lue H, Chen Y, Xiong H, Chagnon F, Bernhagen J, Lolis E, Mor G, Lesur O, Bucala R.
The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF).
Proceedings of the National Academy of Sciences USA 2011; 108:E577-85.
JIF 9.7
149. Anz D, Eiber S, Scholz C, Endres S, Kirchner T, Bourquin C, Mayr D.
In breast cancer a high ratio of tumor-infiltrating intraepithelial CD8+ to FoxP3+ cells is characteristic for the medullary subtype.
Histopathology 2011; 59:965-74.
JIF 2.9
148. Kobold S, Tams S, Luetkens T, Cao Y, Sezer O, Bartels BM, Reinhard H, Templin J, Bartels K, Hildebrandt Y, Lajmi N, Marx A, Haag F, Bokemeyer C, Kröger N, Atanackovic D.
Patients with multiple myeloma develop SOX2-Specific autoantibodies after allogeneic stem cell transplantation.
Clinical and Developmental Immunology 2011; 2011:302145.
JIF 3.1
148. Bourquin C, Hotz C, Noerenberg D, Völkl A, Heidegger S, Storch B, Sandholzer N,
Wurzenberger C, Anz D, Endres S.
Systemic cancer therapy with a small molecule agonist of Toll-like receptor 7 can be improved by circumventing TLR tolerance.
Cancer Research 2011; 71:5123-33.
JIF 8.7
147. Duewell P, Kisser U, Heckelsmiller K, Hoves S, Stoitzner P, Morelli AB, Koernig S, Clausen BE, Dauer M, Eigler A, Anz D, Bourquin C, Maraskovsky E, Endres S, Schnurr M.
ISCOMATRIX adjuvant combines immune activation with antigen delivery to dendritic cells in vivo leading to effective cross-priming of CD8+ T cells.
Journal of Immunology 2011; 187:55-63.
JIF 5.5
146. Bauer C, Dauer M, Saraj S, Bauernfeind F, Sterzik A, Junkmann J, Jakl V, Kiefl R, Schnurr M, Oduncu F, Emmerich B, Mussack T, Bruns C, Rüttinger D, Conrad C, Jauch KW, Endres S, Eigler A.
Dendritic cell-based vaccination of patients with advanced pancreatic carcinoma: results of a pilot study.
Cancer Immunology Immunotherapy 2011; 60:1097-107.
JIF 3.6
145. Zoglmeier C, Bauer H, Noerenberg D, Wedekind G, Bittner P, Sandholzer N, Rapp M, Anz D, Endres S, Bourquin C.
CpG blocks immune suppression by myeloid-derived suppressor cells in tumor-bearing mice. (see editorial: Lechner M, Epstein A. A new mechanism for blocking myeloid-derived suppressor cells by CpG. Clin Canc Res 2011 Feb.)
Clinical Cancer Research 2011; 17:1765-75.
JIF 7.8
144. Anz D, Mueller W, Golic M, Kunz WG, Rapp M, Koelzer VH, Ellermeier J, Ellwart JW, Schnurr M, Bourquin C, Endres S.
CD103 is a hallmark of tumor-infiltrating regulatory T cells.
International Journal of Cancer 2011;129:2417-26.
JIF 6.2
143. Jacobs C, Duewell P, Heckelsmiller K, Wei J, Bauernfeind F, Ellermeier J, Kisser U, Bauer C, Dauer M, Eigler A, Maraskovsky E, Endres S, Schnurr M.
An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma.
International Journal of Cancer 2011; 128:897-907.
JIF 6.2
2010
142. Bourquin C, Wurzenberger C, Heidegger S, Fuchs S, Anz D, Weigel S, Sandholzer N, Winter G, Coester C, Endres S.
Delivery of immunostimulatory RNA oligonucleotides by gelatin nanoparticles triggers an efficient antitumoral response.
Journal of Immunotherapy 2010; 339:935-44.
JIF 3.5
141. Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nunez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E.
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Nature 2010; 464:1357-6.
JIF 38.6
141. Bourquin C, von der Borch P, Zoglmeier C, Anz D, Sandholzer N, Wurzenberger C, Denzel A, Kammerer R, Zimmermann R, Endres S.
Efficient eradication of subcutaneous but not of autochthonous gastric tumors by adoptive T cell transfer in a SV40 T antigen mouse model.
Journal of Immunology 2010; 185:2580-8.
JIF 5.5
140. Bauer C, Duewell P, Mayer T, Lehr HA, Fitzgerald KA, Tschopp J, Endres S, Latz E, Schnurr M.
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NALP3 inflammasome.
Gut 2010; 59:1192-9.
JIF 10.7
139. Anz D, Koelzer VH, Moder S, Thaler R, Schwerd T, Lahl K, Sparwasser T, Besch R, Poeck H, Hornung V, Hartmann G, Rothenfusser S, Bourquin C, Endres S.
Immunostimulatory RNA blocks suppression by regulatory T cells.
Journal of Immunology 2010; 184:939-46.
JIF 5.5
2009
138. Poeck H, Bscheider M, Gross O, Finger K, Roth S, Rebsamen M, Hannesschläger N, Schlee M, Rothenfusser S, Barchet W, Kato H, Akira S, Inoue S, Endres S, Peschel C, Hartmann G, Hornung V, Ruland J.
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin-1β production.
Nature Immunology 2009; 11:63-9.
JIF 26.2
137. Berchthold C, Panthel K, Jellbauer S, Köhn B, Roider E, Partilla M, Heesemann J, Endres S, Bourquin C, Rüssmann H.
Superior protective immunity against murine listeriosis by combined vaccination with CpG DNA and recombinant salmonella.
Infection and Immunity 2009; 77:5501-5508.
JIF 4.1
136. Bourquin C, Schmidt L, Lanz AL, Storch B, Wurzenberger C, Anz D, Berger M, Poeck H, Hartmann G, Hornung V, Endres S.
Immunostimulatory RNA oligonucleotides induce an effective antitumoral NK cell response through TLR7.
Journal of Immunology 2009; 183:6078-86.
JIF 5.5
135. Berger M, Ablasser A, Kim S, Bekeredjian-Ding I, Giese T, Endres S, Hornung V, Hartmann G.
TLR8-driven IL-12-dependent reciprocal and synergistic activation of NK cells and monocytes by immunostimulatory RNA.
Journal of Immunotherapy 2009; 32:262-71.
JIF 3.5
134. Schmidt A, Schwerd T, Hellmuth J, Sheng C, Wenzel M, Hoffmann F, Poeck H, Michallet MC, Besch R, Hopfner KP, Endres S, Rothenfusser S.
5'-triphosphate RNA requires base-paired structures to activate anti-viral signaling via RIG-I.
Proceedings of the National Academy of Sciences USA 2009; 106:12067-72.
JIF 9.7
133. Besch R, Poeck H, Hohenauer T, Senft D, Haecker G, Berking C, Hornung V, Endres S, Ruzicka T, Rothenfusser S, Hartmann G.
Proapoptotic signalling by RIG-I and MDA-5 results in tumorspecific apoptosis independent of type I interferons in melanoma.
Journal of Clinical Investigation 2009; 119:2399-411.
JIF 12.8
132. Ablasser A, Poeck H, Berger M , Schlee M, Kim S, Bourquin C, Goutagny N, Jiang Z, Fitzgerald KA, Anz D, Rothenfusser S , Endres S , Hartmann G, Hornung V.
Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes.
Journal of Immunology 2009; 182:6824-33.
JIF 5.5
131. Bekeredjian-Ding I, Schaefer M, Hartmann E, Pies R, Parcina M, Schneider P, Giese T, Endres S, Wollenberg B, Hartmann G.
Tumour-derived prostaglandin E2 and transforming growth factor-β synergize to inhibit plasmacytoid dendritic cell-derived interferon-α.
Immunology 2009; 128:439-450.
JIF 3.7
130. Haasters F, Prall WC, Anz D, Endres S, Mutschler M, Dochenva D, Schieker M.
Morphological and immunological characteristics indicate the yield of early progenitors and represent a quality control for human mesenchymal stem cell culturing.
Journal of Anatomy 2009; 214:759-767.
JIF 2.4
129. Gross O, Poeck H, Bscheider M, Dostert C,Hannesschlaeger N, Endres S, Tardivel A, Tschopp J, Ruland J.
Syk kinase siganling couples to the Nalp3 inflammasome for anti-fungal host defense.
Nature 2009; 459:433-6.
JIF 38.6
128. Anz D, Thaler R, Stephan N,Waibler Z, Trauscheid MJ, Scholz C,Kalinke U, Barchet W, Endres S, Bourquin C.
Activation of melanoma differentiation-associated gene 5 (MDA5) and Toll-like receptors causes rapid involution of thymus.
Journal of Immunology 2009; 182:6044-50.
JIF 5.5
127. Wurzenberger C, Kölzer HV, Schreiber S, Anz D, Vollmar AM, Schnurr M, Endres S, Bourquin C.
Short-term activation induces multifunctional dendritic cells that generate potent antitumor T-cell responses in vivo.
Cancer Immunology Immunotherapy 2009; 58:901-13.
JIF 3.6
126. Schnurr M, Orban M, Robson NC, Shin A, Braley H, Airey D, Cebon J, Maraskovsky E, Endres S.
ISCOMATRIX adjuvant induces efficient cross-presentation of tumor Ag by dendritic cells via rapid cytosolic Ag delivery and processing via tripeptidyl peptidase II .
Journal of Immunology 2009; 182:1253-9.
JIF 5.5
2008
125. Allam R, Pawar RD, Kulkarni OP, Hornung V, Hartmann G, Segerer S, Akira S, Endres S, Anders HJ.
Viral 5'-triphosphate RNA and non CpG DNA aggravate autoimmunity and lupus nephritis via distinct TLR-independent immune responses.
European Journal of Immunology 2008; 38:3487-3498.
JIF 5.0
124. Dauer M, Lam V, Arnold H, Junkmann J, Kiefl R, Bauer C, Schnurr M, Endres S, Eigler A.
Combined use of toll-like receptor agonists and prostaglandin E(2) in the FastDC model: rapid generation of human monocyte-derived dendritic cells capable of migration and IL-12p70 production.
Journal of Immunological Methods 2008; 337:97-105.
JIF 2.2
123. Poeck H, Besch R, Maihoefer C, Renn M, Tormo D, Morskaya S S, Kirschnek S, Gaffal E, Landsberg J, Hellmuth J, Schmidt A, Anz D, Bscheider M, Schwerd T, Berking C, Bourquin C, Kalinke U, Kremmer E, Kato H, Akira S, Meyers R, Häcker G, Neuenhahn M, Busch D H, Rothenfusser S , Prinz M, Hornung V, Endres S, Tüting T, Hartmann G.
Therapeutic anti-tumor efficacy of 5´-triphosphate-siRNA depends on simultaneous gene-silencing and immuno-stimulatory activity.
Nature Medicine 2008; 14:1256-63.
JIF 24.3
122. Bourquin C , Anz D, Zwioreck K, Lanz AL, Fuchs S, Weigel S, Wurzenberger C, von der Borch P, Golic M, Winter G, Endres S.
Targeting CpG oligonucleotides to the lymph node by nanoparticels elicits efficient antitumoral immunity.
Journal of Immunology 2008; 1;181:2990-8.
JIF 5.5
121. Bourquin C, Haar M, Anz D, Sandholzer N, Neumaier I, Endres S, Skerra A, Schwab M, Linington C.
DNA vaccination efficiently induces antibodies to Nogo-A and does not exacerbate experimental autoimmune encephalomyelitis.
European Journal of Pharmacology 2008; 588:99-105.
JIF 2.6
120. Zwiorek K, Bourquin C, Battiany J, Winter G, Endres S, Hartmann G, Coester C.
Delivery by cationic gelatin nanoparticles strongly increases the immunostimulatory effects of CpG Oligonucleotides.
Pharmaceutical Research 2008; 25:551-62.
JIF 4.7
119. Shin A, Toy T, Rothenfusser S, Robson N, Vorac J, Dauer M, Stuplich M, Endres S, CebonJ, Maraskovsky E, Schnurr M.
P2Y receptor signaling regulates phenotype and IFN-α secretion of human plasmacytoid dendritic cells.
Blood 2008; 111:3062-9.
JIF 9.1
2007
118. Bauer C, Bauernfeind F, Sterzik A, Orban M, Schnurr M, Lehr HA, Endres S, Eigler A, Dauer M.
Dendritic cell-based vaccination can be combined with gemcitabine to increase survival in a murine pancreatic carcinoma model.
Gut 2007; 5:1275-82.
JIF 3.0
117. Bauer C, Loher F, Dauer M, Mayer C, Lehr HA, Schönharting M, Hallwachs R, Endres S, Eigler A.
The ICE inhibitor pralnacasan prevents DSS-induced colitis in C57BL/6 mice and suppresses IP-10 mRNA, but not TNF-α expression.
Digestive Diseases and Sciences 2007; 52: 1642-52.
JIF 1.6
116. Bekeredjian-Ding I, Inamura S, Giese T, Moll H, Endres S, Sing A, Zähringer U, Hartmann G.
Staphylococcus aureus triggers T cell-independent B cell proliferation through the engagement of the B cell receptor and Toll-like receptor 2.
Journal of Immunology 2007; 178:2803-12.
JIF 6.7
115. Bourquin C, Schmid L, Hornung V, Wurzenberger C, Anz D, Sandholzer N, Schreiber S, Voelkl A, Hartmann G, Endres S.
Immunostimulatory RNA oligonucleotides trigger an antigen-specific cytoxic T cell and IgG2a response.
Blood 2007; 109: 2953-60.
JIF 10.1
2006
114. Hartmann E, Graefe H, Hopert A, Pries R, Rothenfusser S, Poeck H, Mack B, Endres S,
Hartmann G, Wollenberg B.
Analysis of plasmacytoid and myeloid dendritic cells in nasal epithelium.
Clinical and Vaccine Immunology 2006; 13:1278-86.
JIF 2.6
113. Hornung V, Ellegast J, Kim S, Brzozka K, Jung A, Kato H, Poeck H, Akira S, Conzelmann KK, Schlee M, Endres S, Hartmann G.
5'-triphosphate RNA is the ligand for RIG-I.
Science 2006; 314:994-7.
JIF 30.9
112. Kerkmann M, Lochmann D, Weyermann J, Sarris A, Poeck H, Wagner M, Battiany J, Zimmer A, Endres S, Hartmann G.
Immunostimulatory properties of CpG-oligonucleotides are enhanced by the use of protamine nanoparticles.
Oligonucleotides 2006; 16: 313-22.
JIF 3.1
111. Eigenbrod S, Derwand R, Jakl V, Endres S, Eigler A.
Sphingosine kinase and sphingosine-1-phosphate regulate migration, endocytosis and apoptosis of dendritic cells.
Immunological Investigations 2006; 35:149-65.
JIF 1.2
110. Dauer M, Schad K, Junkmann J, Herten J, Kiefl R, Schnurr M, Endres S, Eigler A.
IFN-α promotes definitive maturation of dendritic cells generated by short term culture of monocytes with GM-CSF and IL-4.
Journal of Leukocyte Biology 2006; 80:278-86.
JIF 4.3
109. Bekeredjian-Ding I, Roth S I, Gilles S, Giese T, Ablasser A, Hornung V, Endres S, Hartmann G.
T cell-independent TLR-induced IL-12p70 production in primary human monocytes.
Journal of Immunology 2006; 176:7438-46.
JIF 6.7
108. Bourquin C, Schreiber S, Beck S, Hartmann G, Endres S.
Immunotherapy with dendritic cells and CpG oligonucleotides can be combined with chemotherapy without loss of efficacy in a mouse model of colon cancer.
International Journal of Cancer 2006; 118:2790-5.
JIF 4.4
2005
107. Dauer M, Schad K, Herten J, Junkmann J, Bauer C, Kiefl R, Endres S, Eigler A.
FastDC derived from human monocytes within 48 hours effectively prime tumor antigen-specific cytotoxic cells.
Journal of Immunological Methods 2005; 302:145-55.
JIF 2.5
106. Marschner A, Rothenfusser S, Hornung V, Prell D, Krug A, Kerkmann M, Wellisch D, Poeck H, Greinacher A, Giese T, Endres S, Hartmann G.
CpG ODN enhance antigen-specific NKT cell activation via plasmacytoid dendritic cells.
European Journal of Immunology 2005; 35:2347-57.
JIF 5.4
105. Dauer M, Herten J, Bauer C, Renner F, Schad K, Schnurr M, Endres S, Eigler A.
Chemosensitization of pancreatic carcinoma cells to enhance T cell-mediated cytotoxicity induced by tumor lysate-pulsed dendritic cells.
Journal of Immunotherapy 2005; 28:332-42.
JIF 4.0
104. Renner ED, Pawlita I, Hornung V, Hartl D, Albert M, Jansson A, Endres S, Hartmann G, Belohradsky BH, Rothenfusser S.
No indication for a defect in Toll like receptor signalling in patients with hyper IgE syndrome.
Journal of Clinical Immunology 2005; 25:321-8.
JIF 2.6
103. Bekeredjian-Ding I, Wagner M, Hornung V, Giese T, Schnurr M, Endres S, Hartmann G.
Plasmacytoid dendritic cells control TLR7 sensivity of naive B cells via type I IFN.
Journal of Immunology 2005; 174:4043-50.
JIF 6.7
102. Hartmann G, Marschner A, Renner-Viveros P, Stahl-Henning C, Eisenblätter M, Suh JS, Endres S, Tenner-Racz K, Racz P, Steinmann R, Ignatius R.
CpG oligonucleotides induce strong humoral but only weak CD4+ T cell responses to protein antigens in rhesus macaques in vivo.
Vaccine 2005; 23:3310-7.
JIF 2.8
101. Schlender J, Hornung V, Finke S, Guenthner-Biller M, Marozin S, Brzozka K, Moghim S, Endres S, Hartmann G, Conzelmann KK.
Inhibition of Toll-like-receptor 7 and 9-mediated type I IFN production in human plasmacytoid dendritic cells by respiratory syncytial virus and mesales Virus.
Journal of Virology 2005; 79:5507-15.
JIF 5.2
100. Hornung V, Guenthner-Biller M,Bourquin C, Ablasser A, Schlee M, Uematsu S, Manoharan M, Akira S, de Fougerolles A, Endres S, Hartmann G.
Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7.
Nature Medicine 2005; 11:263-70.
JIF 30.6
99. Jahrsdorfer B, Mühlenhoff L, Blackwell S E, Wagner M, Poeck H, Hartmann E, Jox R, Giese T, Emmerich B, Endres S, Hartmann G.
B cell lymphomas differ in their responsiveness to CpG oligodeoxynucleotides.
Clinical Cancer Research 2005; 11:1490-9.
JIF 6.5
98. Kerkmann M, Costa LT, Richter C, Rothenfusser S, Battiany J, Hornung V, Johnson J, Englert S, Ketterer T, Heckl W, Thalhammer S, Endres S, Hartmann G.
Spontaneous formation of nucleic acid-based nanoparticles is responsible for high IFN-α induction by CpG-A in plasmacytoid dendritic cells.
Journal of Biological Chemistry 2005; 280:8086-93.
JIF 6.2
2004
97. Hornung V, Schlender J, Guenthner-Biller M, Rothenfusser S, Endres S, Hartmann G.
Replication dependent potent IFN-α induction in human plasmacytoid dendritic cells by a single-stranded RNA virus.
Journal of Immunology 2004; 173:5935-43.
JIF 7.3
96. Costa LT, Kerkmann M, Hartmann G, Endres S, Bisch PM, Heckl WM, Thalhammer S.
Structural studies of oligonucleotides containing G-quadruplex motifs using atomic force microscopy.
Biochemical and Biophysical Research Communication 2004; 313:1065-72.
JIF 3.2
95. Wagner M, Poeck H, Jahrsdoerfer B, Rothenfusser S, Prell D, Bohle B, Tuma E, Giese T, Ellwart JW, Endres S, Hartmann G.
IL-12p70-dependent Th1 induction by human B cells requires combined activation with CD40 ligand and CpG DNA.
Journal of Immunology 2004; 172:954-63.
JIF 7.3
94. Poeck H, Wagner M, Battiany J, Rothenfusser S, Wellisch D, Hornung V, Jahrsdorfer B, Giese T, Endres S, Hartmann G.
Plasmacytoid dendritic cells, antigen, and CpG-C license human B cells for plasma cell differentiation and immunoglobulin production in the absence of T-cell help.
Blood 2004; 103:3058-64.
JIF 10.1
93. Rothenfusser S, Hornung V, Ayyoub M, Britsch S, Towarowski A, Krug A, Sarris A, Lubenow N, Speiser D, Endres S, Hartmann G.
CpG-A and CpG-B oligonucleotides differentially enhance human peptide-specific primary and memory CD8+ T-cell responses in vitro.
Blood 2004; 103:2162-9.
JIF 10.1
92. Loher F, Bauer C, Landauer N, Schmall K, Siegmund B, Lehr HA, Dauer M, Schoenharting M, Endres S, Eigler A.
The interleukin-1 beta-converting enzyme inhibitor pralnacasan reduces dextran sulfate sodium-induced murine colitis and T helper 1 T-cell activation.
Journal of Pharmacological and Experimental Therapeutics 2004; 308:583-90.
JIF 3.4
2003
91. Obermaier B, Dauer M, Herten J, Schad K, Endres S, Eigler A.
Development of a new protocol for 2-day generation of mature dendritic cells from human monocytes.
Biological Procedures Online 2003; 6:197-203.
JIF 2.0
90. Schmidt T, Ziske C, Marten A, Endres S, Tiemann K, Schmitz V, Gorschluter M, Schneider C, Sauerbruch T, Schmidt-Wolf IG.
Intratumoral immunization with tumor RNA-pulsed dendritic cells confers antitumor immunity in a C57BL/6 pancreatic murine tumor model
Cancer Research 2003; 63:8962-7.
JIF 8.4
89. Hartmann E, Wollenberg B, Rothenfusser S, Wagner M, Wellisch D, Mack B, Giese T, Gires O, Endres S, Hartmann G.
Identification and functional analysis of tumor-infiltrating plasmacytoid dendritic cells in head and neck cancer.
Cancer Research 2003; 63:6478-87.
JIF 8.4
88. Dauer M, Pohl K, Obermaier B, Meskendahl T, Röbe J, Schnurr M, Endres S, Eigler A.
Interferon-alpha disables dendritic cell precursors: dendritic cells derived from interferon-α-treated monocytes are defective in maturation and T-cell stimulation.
Immunology 2003; 110:38-47.
JIF 2.7
87. Hartmann G, Battiany J, Poeck H, Wagner M, Kerkmann M, Lubenow N, Rothenfusser S, Endres S.
Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-α induction in plasmacytoid dendritic cells.
European Journal of Immunology 2003; 33:1633-41.
JIF 5.4
86. Kerkmann M, Rothenfusser S, Hornung V, Towarowski A, Wagner M, Sarris A, Giese T, Endres S, Hartmann G.
Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells.
Journal of Immunology 2003; 170:4465-74.
JIF 7.3
85. Dauer M, Obermaier B, Herten J, Haerle C, Pohl K, Rothenfusser S, Schnurr M, Endres S, Eigler A.
Mature dendritic cells derived from human monocytes within 48 hours: a novel strategy for dendritic cell differentiation from blood precursors.
Immunology 2003; 170:4069-76.
JIF 2.7
84. Loher F, Schmall K, Freytag P, Landauer N, Hallwachs R, Bauer C, Siegmund B, Rieder F, Lehr HA, Dauer M, Kapp JF, Endres S, Eigler A.
The specific type-4 phosphodiesterase inhibitor mesopram alleviates experimental colitis in mice.
Journal of Pharmacological and Experimental Therapeutics 2003; 305:549-56.
JIF 3.4
83. Krug A, Rothenfusser S, Selinger S, Bock C, Kerkmann M, Battiany J, Sarris A, Giese T, Speiser D, Endres S, Hartmann G.
CpG-A oligonucleotides induce a monocyte-derived dendritic cell-like phenotype that preferentially activates CD8 T cells.
Journal of Immunology 2003; 170:3468-77.
JIF 7.3
2002
82. Wollenberg A, Wagner M, Gunther S, Towarowski A, Tuma E, Moderer M, Rothenfusser S, Wetzel S, Endres S, Hartmann G.
Plasmacytoid dendritic cells: a new cutaneous dendritic cell subset with distinct role in inflammatory skin diseases.
Journal of Investigative Dermatology 2002; 119:1096-102.
JIF 5.4
81. Heckelsmiller K, Rall K, Beck S, Schlamp A, Seiderer J, Jahrsdorfer B, Krug A, Rothenfusser S, Endres S, Hartmann G.
Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model.
Journal of Immunology 2002; 169:3892-9.
JIF 7.3
80. Heckelsmiller K, Beck S, Rall K, Sipos B, Schlamp A, Tuma E, Rothenfusser S, Endres S, Hartmann G.
Combined dendritic cell- and CpG oligonucleotide-based immune therapy cures large murine tumors that resist chemotherapy.
European Journal of Immunology 2002; 32:3235-45.
JIF 5.4
79. Hornung V, Rothenfusser S, Britsch S, Krug A, Jahrsdorfer B, Giese T, Endres S, Hartmann G.
Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides.
Journal of Immunology 2002; 7:34-44.
JIF 7.3
78. Schnurr M, Scholz C, Rothenfusser S, Galambos P, Dauer M,Röbe J, Endres S, Eigler A.
Apoptotic pancreatic tumor cells are superior to cell lysates in promoting cross-priming of cytotoxic T cells and activate NK and gammadelta T cells.
Cancer Research 2002; 62:2347-52.
JIF 8.4
77. Jahrsdorfer B, Jox R, Muhlenhoff L, Tschoep K, Krug A, Rothenfusser S, Meinhardt G, Emmerich B, Endres S, Hartmann G.
Modulation of malignant B cell activation and apoptosis by bcl-2 antisense ODN and immunostimulatory CpG ODN.
Journal of Leukocyte Biology 2002; 72:83-92.
JIF 4.3
76. Dauer M, Schulze J, Loher F, Endres S, Eigler A.
Determination of thiopurine S-methyltransferase phenotype using thin-layer chromatography and quantitative scanning.
European Journal of Clinical Pharmacology 2002; 58:41-4.
JIF 1.4
75. Zou W, Schwartz H, Endres S, Hartmann G, Bar-Shavit Z.
CpG oligonucleotides: novel regulators of osteoclast differentiation.
FASEB Journal 2002; 16:274-82.
JIF 13.9
2001
74. Howes N, Lerch MM, Mossner J, Endres S, Deviere J, Verreman G, Lucidi V, Charnley R, Imrie C, Hall R, Olah A, Ihse I, Steenbergan W, O'Donnell M, Greenhalf W, Ellis I, Rutherford S, Mountford R, Whitcombe DC, Neoptolemos JP.
High risk of surgical intervention in hereditary pancreatitis.
British Journal of Surgery 2001; 88:475-476.
JIF 2.7
73. Rothenfusser S, Hornung V, Krug A, Towarowski A, Krieg A, Endres S, Hartmann G.
Distinct CpG oligonucleotide sequences activate human gd T cells via interferon-a/-b.
European Journal of Immunology 2001; 31:3525-34.
JIF 5.4
72. Siegmund B, Rieder F, Lehr H.A, Hartmann G, Dinarello C.A, Endres S, Eigler A.
Neutralization of IL-18 decreases in vivo IFNg synthesis and improves experimental colitis in mice.
American Journal of Physiology 2001; 281:1264-73.
JIF 3.7
71. Krug A, Towarowski A, Britsch S, Rothenfusser S, Hornung V, Bahls R, Giese T, Engelmann H, Endres S, Krieg A, Hartmann G.
TLR expression reveals CpG ODN as a unique microbial stimulus for plasmacytoid dendritic cells; synergy with CD40L to induce IL-12p70.
European Journal of Immunology 2001; 31:3026-37.
JIF 5.4
70. Siegmund B, Welsch J, Meinhardt G, Emmerich B, Endres S, Eigler A.
Phosphdiesterase type 4 inhibitor suppresses expression of antiapoptotic members of the Bcl-2 family in B-CLL cells and induces Il-10- and caspase-independent apoptosis.
Leukemia 2001; 15:1564-71.
JIF 3.2
69. Hacker U, Erhardt S, Tschöp K, Jelinek T, Endres S.
Influence of IL-1RA gene polymorphism on in vivo synthesis of IL-1RA and IL-1β after live yellow fever vaccination.
Experimental and Clinical Immunology 2001; 125:465-69.
JIF 2.7
68. Schnurr M, Galambos P, Scholz C, Then F, Dauer M, Endres S, Eigler A.
Tumor cell lysate-pulsed human dendritic cells induce a T cell response against pancreatic carcinoma cells: an in vitro model for the assesment of tumor vaccines.
Cancer Research 2001; 61:6445-50.
JIF 8.4
67. Zou W, Hakim I, Tschoep K, Endres S, Bar-Shavit Z.
Tumor necrosis factor-a mediates RANK ligand stimulation of osteoclast differentiation by autocrine mechanism.
Journal of Cellular Biochemistry 2001; 83:70-83.
JIF 2.8
66. Krug A, Rothenfusser S, Hornung V, Jahrsdörfer B, Blackwell S, Ballas Z, Endres S, Krieg A, Hartmann G.
A new CpG oligonucleotide sequence induces maximal production of IFN-a in plasmacytoid dendritic cells.
European Journal of Immunology 2001; 31:3026-37.
JIF 5.4
65. Tschoep K, Hartmann G, Eigler A, Krug A, Erhardt S, Adams G, Endres S, Delius M.
Shock waves: a novel method for intracytoplasmic delivery of antisense oligonucleotides.
Journal of Molecular Medicine 2001; 79:306-13.
JIF 3.7
64. Siegmund B, Albrich S, Rieder F, Wolf K, Firestein GS, Boyle D, Lehr HA, Hartmann G, Endres S, Eigler A.
Adenosine kinase inhibitor GP515 improves experimental colitis in mice.
Journal of Pharmacological and Experimental Therapeutics 2001; 296:1-6.
JIF 3.4
63. Jahrsdörfer B, Hartmann G, Racila E, Meinhardt G, Endres S, Krieg AM, Weiner GJ.
CPG DNA increases primary malignant B cell expression of costimulatory molecules and target antigens.
Journal of Leukocyte Biology 2001; 69:81-8.
JIF 4.3
2000
62. Brunner C, Seiderer J, Schlamp A, Bidlingmaier M, Eigler A, Haimerl W, Lehr HA, Krieg A,
Hartmann G, Endres S.
Enhanced dentritic cell maturation by TNF-α or cytidine-phosphate-guanosine DNA drives cell activation in vitro and therapeutic anti-tumor immune responses in vivo.
Journal of Immunology 2000; 165:6278-86.
JIF 7.3
61. Schnurr M, Then F, Galambos P, Scholz C, Siegmund B, Endres S, Eigler A.
Extracellular ATP and TNF-α synergize in the acivation and maturation of human dentritic cells.
Journal of Immunology 2000; 165:4704-9.
JIF 7.3
60. Eigler A, Matschke V, Hartmann G, Erhardt S, Boyle D, Firestein GS, Endres S.
Suppression of TNF-α production in human mononuclear cells by an adenosine kinase inhibitor.
Journal of Leukocyte Biology 2000; 68:97-103.
JIF 4.3
59. Hartmann G, Tschöp M, Bidlingmaier C, Fischer R, Riepl R, Tschöp K, Hautmann H, Endres S, Toepfer M.
High altitude increases circulating interleukin-6, interleukin-1 receptor antagonist and C-reactive protein.
Cytokine 2000; 12:246-52.
JIF 2.7
58. Hartmann G, Bidlingmaier C, Siegmund B, Albrich S, Schulze J, Tschöp K, Eigler A, Lehr HA, Endres S.
The specific type IV phosphodiesterase inhibitor rolipram mitigates experimental colitis in mice.
Journal of Pharmacology and Experimental Therapeutics 2000; 292:22-30.
JIF 3.9
57. Tuma E, Eigler A, Toepfer M, Endres S, Schiffl H.
IL-1 receptor antagonist production by isolated mononuclear cells is a better indicator of bioincompatibility of hemodialysis membranes than that by stimulated whole blood.
Nephron 2000; 86:220-221.
JIF 1.9
1999
56. Schulze J, Töpfer M, Schroff K-C, Aschhoff S, Remlen J, Müller-Felber W, Endres S.
Clindamycin and nicotinic neuromuscular transmission (research letter).
The Lancet 1999; 354:1792-93.
JIF 17.9
1998
55. Sinha B, Eigler A, Baumann KH, Greten TF, Moeller J, Endres S.
Nitric oxide downregulates tumour necrosis factor mRNA in Raw 264.7 cells.
Research in Immunology 1998; 149:139-50.
JIF 1.1
54. Hartmann G, Bidlingmaier M, Jahrsdörfer B, Krug A, Hacker U, Eigler A, Endres S.
Oligonucleotide uptake in leukocytes is dependent on extracellular calcium: A hint for the involvement of adhesion molecules?
Nucleosides and Nucleotides 1998; 17:1767-73.
JIF 1.0
53. Hacker UT, Bidlingmaier C, Gomolka M, Keller E, Eigler A, Hartmann G, Folwaczny C, Fricke H, Albert E, Loeschke K, Endres S.
Inflammatory bowel diesease: no linkage disequilibrium between allelic polymorphisms of interleukin-1β and IL-1 receptor antagonist genes.
European Journal of Clinical Investigation 1998; 28:214-19.
JIF 2.2
52. Siegmund B, Eigler A, Hartmann G, Hacker UT, Endres S.
Adrenaline enhances LPS-induced IL-10 synthesis: evidence for a protein kinase A-mediated pathway.
International Journal of Immunopharmacology 1998; 20:57-69.
JIF 1.0
51. Eigler A, Waller-Fontaine K, Moeller J, Hartmann G, Hacker UT, Endres S.
The hairy cell leukemia cell line Eskol spontaneously synthesizes tumor necrosis factor-a and nitric oxide.
Leukemia Research 1998; 22:501-7.
JIF 1.2
50. Hartmann G, Krug A, Bidlingmaier M, Hacker UT, Eigler A, Albrecht R, Endres S.
Spontaneous and cationic lipid-mediated uptake of antisense oligonucleotides in human monocytes and lymphocytes.
Journal of Pharmacology and Experimental Therapeutics 1998; 285:920-8.
JIF 3.9
49. Eigler A, Siegmund B, Emmerich U, Baumann KH, Hartmann G, Endres S.
Anti-inflammatory activities of cAMP-elevating agents: enhancement of interleukin-10 synthesis and concurrent suppression of tumor necrosis factor production.
Journal of Leukocyte Biology 1998; 63:1-7.
JIF 4.3
48. Hacker UT, Jelinek T, Erhardt S, Eigler A, Hartmann G, Endres S.
In vivo synthesis of tumor necrosis factor-a in healthy humans after live yellow fever vaccination.
Journal of Infectious Diseases 1998; 177:774-8.
JIF 5.4
1997
47. Folwaczny C, Fricke H, Endres S, Hartmann G, Spannagl M, Jochum M, Loeschke K.
Anti-inflammatory properties of unfractioned heparin in patients with highly active ulcerative colitis: a pilot study.
American Journal of Gastroenterology 1997; 92:911-2.
JIF 3.2
46. Hacker UT, Gomolka M, Keller E, Eigler A, Folwaczny C, Fricke H, Albert E, Loeschke K, Endres S.
Lack of association between a polymorphism in the interleukin-1-receptor-antagonist gene and ulcerative colitis.
Gut 1997; 40:623-7.
JIF 3.0
45. Siegmund B, Eigler A, Sinha B, Moeller J, Hartmann G, Endres S.
Suppression of tumor necrosis factor-a production by interleukin-10 is enhanced by cAMP-elevating agents.
European Journal of Pharmacology 1997; 321:231-9.
JIF 2.3
44. Eigler A, Greten TF, Sinha B, Haslberger C, Sullivan GW, Endres S.
Endogenous adenosine curtails lipopolysaccharide-stimulated tumor necrosis nactor synthesis.
Scandinavian Journal of Immunology 1997; 45:132-9.
JIF 1.9
1996
43. Müller C, Jelinek T, Endres S, Loeschke K.
Schwere protrahierte Cholestase nach Allgemeinanästhesie bei einer Patientin mit Alagille-Syndrom.
Zeitschrift für Gastroenterologie 1996; 34:809-12.
JIF 1.0
42. Hartmann G, Waller-Fontaine K, Eigler A, Moeller J, Krug A, Murphy J, AlbrechtR, Endres S.
Specific suppression of human tumor necrosis factor-a synthesis by antisense oligodeoxynucleotides.
Antisense and Nucleic Acid Drug Development 1996; 6:291-9.
JIF 4.0
41. Milani RV, Mandeep RM, Endres S, Eigler A, Cooper ES, Lavie CJ, Ventura HO.
The clinical relevance of circulating tumor necrosis factor-a in acute decompensated chronic heart failure without cachexia.
Chest 1996; 110:992-5.
JIF 1.8
40. Hartmann G, Krug A,Waller-Fontaine K, Endres S.
Oligodeoxynucleotides enhance LPS-stimulated synthesis of tumor necrosis factor: Dependence on phosphorothioate modification and reversal by heparin.
Molecular Medicine 1996; 2:429-38.
JIF 4.0
39. Greten FT, Moeller J, Feldmeier H, Eigler A, Endres S.
Synthesis of tumour necrosis factor-a in tissue culture of rat coecum: lack of suppression by phosphodiesterase inhibitors.
European Journal of Gastroenterology and Hepatology 1996; 8:679-84.
JIF 0.8
38. Greten FT, Sinha B, Haslberger C, Eigler A, Endres S.
Cicaprost and the specific type IV phosphodiesterase inhibitor rolipram synergize in suppression of tumor necrosis factor-a synthesis.
European Journal of Pharmacology 1996; 299:229-33.
JIF 2.3
37. Endres S, Whitaker RE, Ghorbani R, Meydani SN, Dinarello CA.
Oral aspirin or ibuprofen increase ex vivo cytokine synthesis.
Immunology 1996; 87:264-70.
JIF 2.9
36. Gröttrup-Wolfers E, Moeller J, Karbach U, Müller-Lissner S, Endres S.
Elevated cell-associated levels of interleukin-1β and interleukin-6 in inflamed mucosa of inflammatory bowel disease.
European Journal of Clinical Investigation 1996; 26:115-22.
JIF 2.2
1995
35. Angel JB, Saget BM, Walsh SP, Greten TF, Dinarello CA, Skolnik P, Endres S.
Rolipram, a specific type IV phosphodiesterase inhibitor, is a potent inhibitor of HIV-1 replication.
AIDS 1995; 9:1137-44.
JIF 6.0
34. Greten TF, Eigler A, Sinha B, Moeller J, Endres S.
The specific type IV phosphodiesterase inhibitor rolipram differentially regulates the proinflammatory mediators TNF-α and nitric oxide.
International Journal of Immunopharmacology 1995; 17:605-10.
JIF 1.0
33. Eigler A, Moeller J, Endres S.
Exogenous and endogenous nitric oxide attenuates tumor necrosis factor synthesis in the murine macorphage cell line RAW 264.7.
Journal of Immunology 1995; 154:4048-54.
JIF 7.3
32. Sinha B, Semmler J, Haen E, Moeller J, Endres S.
Radioimmunoassays for cyclic AMP cross react with phosphodiesterase inhibitors and buffer components.
Journal of Pharmacological and Toxicological Methods 1995; 34:29-36.
JIF 1.1
31. Sinha B, Semmler J, Eisenhut T, Eigler A, Endres S.
Enhanced tumor necrosis factor suppression and cyclic adenosine monophosphate accumulation by combination of phosphodiesterase inhibitors and prostanoids.
European Journal of Immunology 1995; 25:147-53.
JIF 5.7
1994
30. Endres S, Sinha B, Stoll D, Fülle HJ.
Amrinone suppresses synthesis of tumor necrosis factor by mononuclear cells in vitro.
Shock 1994; 1:377-80.
JIF 1.3
29. Siebeck M, Kohl J, Endres S, Spannagl M, Machleidt W.
Delayed treatment with platelet-activating factor receptor antagonist WEB 2086 attenuates pulmonary dysfunction in porcine endotoxin shock.
Journal of Trauma 1994; 37:745-51.
JIF 2.3
1993
28. Eigler A, Sinha B, Endres S.
Nitric oxide-releasing agents enhance cytokine-induced tumor necrosis factor synthesis in human mononuclear cells.
Biochemical and Biophysical Research Communication 1993; 196:494-501.
JIF 3.2
27. Endres S, Meydani SN, Ghorbani R, Schindler R, Dinarello CA.
Dietary n-3 fatty acids suppress interleukin‑2 production and mononuclear cell proliferation.
Journal of Leukocyte Biology 1993; 54:599-603.
JIF 4.3
26. Eisenhut T, Sinha B, Gröttrup-Wolfers E, Semmler J, Siess W, Endres S.
Prostacyclin analogs suppress the synthesis of tumor necrosis factor-a in LPS-stimulated human peripheral blood mononuclear cells.
Immunopharmacology 1993; 26:259-64.
JIF 1.8
25. Semmler J, Wachtel H, Endres S.
The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-a production by human mononuclear cells.
International Journal of Immunopharmacology 1993; 15:409-13.
JIF 1.1
24. Semmler J, Gebert U, Eisenhut T, Moeller J, Schönharting MM, Alléra A, Endres S.
Xanthine derivatives: Comparison between suppression of tumour necrosis factor-a production and inhibition of cAMP phosphodiesterase activity.
Immunology 1993; 78:520-5.
JIF 2.9
23. Markewitz A, Faist E, Lang S, Endres S, Hültner L, Reichart B.
Regulation of acute phase response after cardiopulmonary bypass by immunomodulation.
The Annals of Thoracic Surgery 1993; 55:389-94.
JIF 1.6
1992
21. Nerad JL, Griffiths JK, van der Meer JWM, Endres S, Poutsiaka DD, Keusch GT, Bennish M, Salam MA, Dinarello CA, Cannon JG.
Interleukin-1β (IL-1β), IL-1 receptor antagonist, and TNFa production in whole blood.
Journal of Leukocyte Biology 1992; 52:200-5.
JIF 3.6
20. Ziegler-Heitbrock HWL, Blumenstein M, Käfferlein E, Kieper D, Petersman I, Endres S, Flegel W, Northoff H, Riethmüller G, Haas JG.
In vitro desensitization to LPS suppresses TNF, IL-1 and IL-6 gene expression in a similar fashion.
Immunology 1992; 75:264-8.
JIF 2.8
1991
19. Meydani SN, Endres S, Woods MM, Goldin BR, Soo C, Morrill-Labrode A, Dinarello CA, Gorbach SL.
Oral n-3 fatty acid supplementation suppresses cytokine production and lymphocyte proliferation: comparison in young and older women.
Journal of Nutrition 1991; 121:547-55.
JIF 1.9
18. Endres S, Fülle HJ, Sinha B, Stoll D, Dinarello CA, Gerzer R, Weber PC.
Cyclic nucleotides differentially regulate the synthesis of tumor necrosis factor-a and interleukin-1β in human mononuclear cells.
Immunology 1991; 72:56-60.
JIF 2.8
1990
17. Munoz C, Endres S, van der Meer JWM, Schlesinger L, Arevalo M, Dinarello CA.
Interleukin-1β in human collostrum.
Research in Immunology 1990; 141:505-513.
JIF 1.3
16. Park MM, Hornback NB, Endres S, Dinarello CA.
The effect of whole body hyperthermia on the immune cell activity of cancer patients.
Lymphokine Research 1990; 9:213-23.
JIF 2.6
15. Cannon JG, Tompkins RG, Gelfand JA, Michie HR, Stanford GG, van der MeerJWM, Endres S, Lonneman G, Corsetti J, Chernow B, Wilmore DW, Wolff SM, Burke JF, Dinarello CA.
Circulating interleukin‑1 in septic shock and experimental endotoxin fever.
Journal of Infectious Diseases 1990; 161:79-84.
JIF 4.9
14. Schindler R, Mancilla GJ, Endres S, Ghorbani R, Clark SC, Dinarello CA.
Correlation and interaction in the production of IL‑6, IL‑1 and TNF in human blood mononuclear cells: IL‑6 suppresses IL‑1 and TNF.
Blood 1990; 75:40-7.
JIF 8.6
1989
13. Endres S, Cannon JG, Ghorbani R, Dempsey RA, Sisson SD, Lonnemann G, vanderMeerJWM, Wolff SM, Dinarello CA.
In vitro production of IL‑1β, IL-1α, TNF αnd IL‑2 in healthy subjects: distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation.
European Journal of Immunology 1989; 19:2327-33.
JIF 6.0
12. Lonnemann G, Endres S, van der Meer JWM, Cannon JG, Koch KM, Dinarello CA.
Differences in the synthesis and kinetics of release of interleukin‑1α, interleukin‑1β and tumor necrosis factor from human mononuclear cells.
European Journal of Immunology 1989; 19:1531-6.
JIF 6.0
11. Endres S, Ghorbani R, Kelley VE, Georgilis K, Lonnemann G, van der MeerJWM, Cannon JG, Rogers TS, Klempner MS, Weber PC, Schaefer EJ, Wolff SM, DinarelloCA.
The effect of dietary supplementation with n‑3 polyunsaturated fatty acids on the synthesis of interleukin‑1 and tumor necrosis factor by mononuclear cells.
New England Journal of Medicine 1989; 320:265‑71.
JIF 22.4
1988
10. Cannon JG, van der Meer JWM, Kwiatkowski D, Endres S, Lonnemann G, Burke JF, Dinarello CA.
Interleukin-1β in human plasma: Optimization of blood collection, plasma extraction and radioimmunoassay methods.
Lymphokine Research 1988; 7:457‑67.
JIF 2.6
9. Okusawa S, Yancey KB, van der Meer JWM, Endres S, Lonnemann L, Hefter K, Frank MM, Burke JF, Dinarello CA, Gelfand JA.
C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro: Comparison with secretion of interleukin-1β and interleukin-1α.
Journal of Experimental Medicine 1988; 168:443‑9.
JIF 15.0
8. Endres S, Ghorbani R, Lonnemann G, van der Meer JWM, Dinarello CA.
Measurement of immunoreactive interleukin-1β from human mononuclear cells: optimization of recovery, intrasubject consistency and comparison with interleukin-1α and tumor necrosis factor.
Clinical Immunology and Immunopathology 1988; 49:424‑38.
JIF 2.1
7. Lonnemann G, Endres S, van der Meer JWM, Cannon JG, Dinarello CA.
A radioimmunoassay for human interleukin‑1α: Measurement of IL-1α produced in vitro by human blood mononuclear cells stimulated with endotoxin.
Lymphokine Research 1988; 7:75‑85.
JIF 2.6
6. Boswell JM, Yui MA, Endres S, Burt DW, Kelley VE.
Novel and enhanced interleukin‑1 gene expression in autoimmune mice with lupus.
Journal of Immunology 1988; 141:118‑24.
JIF 7.4
5. Armanini D, Endres S, Kuhnle U, Weber PC.
Parallel determination of mineralocorticoid and glucocorticoid receptors in T‑ and B‑lymphocytes of human spleen.
Acta Endocrinologica 1988; 118:479‑82.
JIF 2.2
4. van der Meer JWM, Endres S, Lonnemann G, Cannon JG, Ikejima T, Okusawa S, Gelfand JA, Dinarello CA.
Concentrations of immunoreactive human tumor necrosis factor a produced by human mononuclear cells in vitro.
Journal of Leukocyte Biology 1988; 43:216‑23.
JIF 3.6
1987
3. Okusawa S, Dinarello CA, Yancey KB, Endres S, Lawley TJ, Frank MM, Burke JF, Gelfand JA.
C5a induction of human interleukin-1. Synergistic effect with endotoxin or interferon‑γ.
Journal of Immunology 1987; 139: 2635‑40.
JIF 7.4
3. Lisi PJ, Chee‑Wui C, Koch GA, Endres S, Lonnemann G, Dinarello CA.
Development and use of a radioimmunoassay for human interleukin-1β.
Lymphokine Research 1987; 6:229‑44.
JIF 2.6
1983
1. Endres S.
Antigenexpression auf aktivierten T-Lymphozyten.
Dissertation, LMU München 1983;
Annual Reports
Reviews
2022
72. Andreu-Sanz D, Kobold S.
Role and promises of different T helper cell subsets in adoptive cell therapy.
Molecular Cancer Biology 2022
JIF 6.6
72. Kandra P, Nandigama R, Eul B, Huber M, Kobold S, Seeger W, Grimminger F, Savai R.
Utility and drawbacks of chimeric antigen receptor T Cell (CAR-T) therapy in lung cancer.
Frontiers in Immunology 2022
JIF 8.8
72. Dalloul I, Strzalkowski T, von Bergwelt-Baildon M, Nüssler V, Zielinski Ch, Kobold S.
9th Immunotherapy of cancer conference (ITOC): a meeting report.
Human Vaccines & Immunotherapeutics 2022
JIF 4.5
72. Drude N, Martinez-Gamboa L, Danzinger M, Collazo A, Kniffert S, Wiebach J, Nilsonne G, Konietschke F, Piper SK, Pawel S, Micheloud Ch, Held L, Frommlet F, Segelcke D, Pogatzki‐Zahn, EM, Voelkl B, Friede T, Brunner E, Dempfle A, Haller B, Jung MJ, Riecken LB, Kuhn HG, Tenbusch M, Serna Higuita LM, Remarque E, Grüninger‐Egli SL, Manske K, Kobold S, Rivalan M, Wedekind L, Wilcke J, Boulesteix AL, Meinhardt M, Spanagel R, Hettmer S, von Lüttichau I, Regina C, Dirnagl U, Toelch U.
Planning preclinical confirmatory multicenter trials to strengthen translation from basic to clinical research.
Translational Medicine Communications 2022, in press.
JIF 8.4
72. Michaelides S, Obeck H, Kechur D, Endres S, Kobold S.
Migratory engineering of T cells for cancer therapy.
Vaccines 2022, in press.
JIF 5.0
71. Tartour E, Mabrouk N, Tran T, Pourmir I, Gruel N, Granier C, Pineau J, Gey A, Kobold S, Fabre E.
CXCR6 expressing T cells: functions and role in the control of tumors.
Frontiers in Immunology 2022, 13:1022136.
JIF 8.8
71. Huynh D, Winter P, Märkl F, Endres S, Kobold S.
Beyond direct killing – novel cellular immunotherapeutic strategies to reshape the tumor microenvironment.
Seminars in Immunopathology 2022; in press.
JIF 11.8
70. Märkl F, Huynh D, Endres S, Kobold S.
Utilizing chemokines in cancer immunotherapy.
Trends in Cancer 2022; 8:670-682.
JIF 14.2
69. Dorman K, Heinemann V, Kobold S, von Bergwelt-Baildon M, Böck S.
Novel systemic treatment approaches for metastatic pancreatic cancer.
Expert Opinion On Investigational Drugs 2022; 31:249-262.
JIF 6.2
69. Stock S, Kluever AK, Endres S, Kobold S.
Enhanced chimeric antigen receptor T cell therapy through co-application of synergistic combination partners.
Biomedicines 2022; 10:307.
JIF 6.1
2021
68. Umut Ö, Gottschlich A, Endres S, Kobold S.
CAR T cell therapy in solid tumors: a short review.
Magazine of European Medical Oncology 2021; 14:143-149.
JIF 1.0
67. Dezfouli A, Yazdi M, Pockley A, Khosravi M, Kobold S, Wagner E, Multhoff G.
NK cells armed with chimeric antigen receptors (CAR): roadblocks to successful development.
Cells 2021; 10:3390.
JIF 6.7
67. Briukhovetska D, Doerr J, Endres S, Libby P, Dinarello Ch, Kobold S.
Interleukins in cancer: from biology to therapy.
Nature Reviews Cancer 2021; 3. Juni 2021
JIF 53.0
https://www.nature.com/articles/s41568-021-00363-z
https://www.lmu-klinikum.de/aktuelles/pressemitteilungen/mit-interleukinen-gegen-den-krebs/94565a179b3a2184
66. Schwerdtfeger M, Desiderio V, Kobold S, Regad T, Zappavigna S, Caraglia M.
Long non-coding RNAs in cancer stem cells.
Translational Oncology 2021; 16:218-233.
JIF 4.1
66. Schwerdtfeger M, Benmebarek MR, Endres S, Subklewe M, Desiderio V, Kobold S.
Chimeric antigen receptor–modified T cells and T cell–engaging bispecific antibodies: different tools for the same job.
Current Hematologic Malignancy Reports 2021
65. Kobold S.
An in sitro assay to predict primary resistance to PD-1 blockade.
Trends in Molecular Medicine 2021; 27:297-298.
JIF 11.1
https://www.sciencedirect.com/science/article/pii/S147149142100037X?dgcid=author
65. Gottschlich A, Endres S, Kobold S.
Therapeutic strategies for targeting IL-1 in cancer.
Cancers 2021; 13:477.
JIF 6.1
https://www.mdpi.com/2072-6694/13/3/477/pdf
64. Patton E, Mueller K, Adams D, Anandasabapathy N, Aplin A, Bertolotto C, Bosenberg M, Ceol C, Chi P, Herlyn M, Holmen S, Karreth F, Kaufman Ch, Khan S, Kobold S, Leucci E, Levy C, Lombard D, Lund A, Marie K, Marine JCh, Marais R, McMahon M, Robles- Espinoza CD, Ronai Z, Samuels Y, Soengas M, Villanueva J, Weeraratna A, White R, Yeh I, Zhu J, Zon L, Hurlbert M, Merlino G.
Melanoma models for the next generation of therapies.
Cancer Cell 2021; 39:610-631.
JIF2020 26.6
2020
64. Koenig L, Boehmer D, Metzger P, Schnurr M, Endres S, Rothenfusser S.
Blocking inflammation on the way: rationale for CXCR2 antagonists for the treatment of COVID-19.
Journal of Experimental Medicine 2020; 217:e20201342.
JIF 10.9
63. Kruger S, Cadilha B, von Bergwelt-Baildon M, Endres S, Kobold S.
Challenges in clinical trial design for T cell-based cancer immunotherapy.
Clinical Pharmacology & Therapeutics 2020; 107:47-49.
JIF 8.7
2019
62. Lesch S, Benmebarek MR, Cadilha B, Stoiber S, Subklewe M, Endres S, Kobold S.
Determinants of response and resistance to CAR T cell therapy.
Seminars in Cancer Biology 2019
JIF 9.7
61. Pinto C, Bergmann M, Briukhovetska D, Nuessler V, Sznol M, von Bergwelt-Baildon M, Kobold S.
6th Immunotherapy of cancer conference (ITOC): advances and perspectives, a meeting report.
Journal for ImmunoTherapy of Cancer 2019
JIF 8.7
61. Pinto C, Bergmann M, Briukhovetska D, Nuessler V, Sznol M, von Bergwelt-Baildon M, Kobold S.
6th Immunotherapy of cancer conference (ITOC): advances and perspectives, a meeting report.
Journal for ImmunoTherapy of Cancer 2019
JIF 8.7
61. Orth M, Metzger P, Gerum S, Mayerle J, Schneider G, Belka C, Schnurr M, Lauber K.
Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches.
Radiation Oncology 2019; 14:141.
JIF 2.9
61. Kruger S, Ilmer M, Kobold S, Cadilha B, Endres S, Ormanns S, Schuebbe G, Renz W, D´Haese J, Schloesser H, Heinemann V, Subklewe M, Boeck S, Werner J, von Bergwelt-Baildon M.
Advances in cancer immunotherapy 2019 – latest trends.
Journal of Experimental and Clinical Research 2019; 38:268.
JIF 6.2
60. Stoiber S, Cadilha B, Benmebarek MR, Lesch S, Endres S, Kobold S.
Limitations in the design of chimeric antigen receptors for cancer therapy.
Cells 2019; 8:E472:1-26
JIF 7.6
59. Darowski D, Kobold S, Jost C, Klein C.
Combining the best of two worlds: Highly flexible chimeric antigen receptor adaptor molecules (CAR-adaptors) for the recruitment of chimeric antigen receptor T cells.
Monoclonal Antibodies 2019; 20:1-11
JIF 5.2
https://doi.org/10.1080/19420862.2019.1596511
59. Benmebarek MR, Karches C, Cadilha B, Lesch S, Endres S, Kobold S*.
Killing mechanisms of chimeric antigen receptor (CAR) T cells.
International Journal of Molecular Sciences 2019; 20(6)
JIF 3.7
https://www.ncbi.nlm.nih.gov/pubmed/?term=Benmebarek+MR
58. Kobold S.
Innate and adaptive immunity combined for cancer treatment. (comment)
Proceedings of the National Academy of Sciences USA 2019, 116:1087-1088
JIF 9.5
58. Tokarew N, Ogonek J, Endres S, von Bergwelt-Baildon M, Kobold S.
Teaching an old dog new tricks: next generation CAR T cells.
British Journal of Cancer 2019; 120:26-37
JIF 6.2
57. Duewell P, Endres S, Kobold S.
Innate immune stimulation in cancer therapy.
Hematology/Oncology Clinics of North America 2018
JIF 3.1
56. Zhang J, Endres S, Kobold S.
Enhancing T cell infiltration to enable cancer immunotherapy.
Immunotherapy 2018
JIF 3.5
2018
55. Kobold S, Pantelyushin S, Rataj F, vom Berg J.
Rationale for combining bispecific T cell activating antibodies with checkpoint blockade for cancer therapy.
Frontiers Oncology 2018; 9:1955
JIF 2.0
55. Kobold S, Krackhardt A, Schlösser H, Wolf D.
Immuno-Oncology: A Brief Overview
Deutsche Medizinische Wochenschrift 2018, 143:1006-1013.
JIF 0.6
54. Markota A, Endres S, Kobold S.
Targeting interleukin-22 for cancer therapy.
Human Vaccines & Immunotherapeutics 2018; 14:2012-2015
JIF 2.2
53. Rataj F, Endres S, Kobold S.
When the inhibitor is turned into stimulator: novel aspects in T cell engineering.
Translational Cancer Research 2018
JIF 1.8
52. Gottschlich A, Endres S, Kobold S.
Can we use interleukin-1ß blockade for lung cancer treatment?
Translational Lung Cancer Research 2018; 7:160-164
JIF 1.8
2017
51. Kobold S.
Komplexe Biosimilars in der Onkologie. Rituximab, Trastuzumab & co.
TZM News 2017; Ausgabe 4
51. Cadilha B, Dorman K, Rataj F, Endres S, Kobold S.
Enabling T cell recruitment to tumors as a strategy for improving adoptive T cell therapy.
European Oncology and Haematology 2017; 13:66-73.
2016
50. Bauer C, Kuehnemuth B, Duewell P, Ormanns S, Gress T, Schnurr M.
revailing over T cell exhaustion: New developments in the immunotherapy of pancreatic cancer.
Cancer Letters 2016
JIF 6,0
http://dx.doi.org/10.1016/j.canlet.2016.02.057
50. Kobold S, Endres S.
Prinzipien der Immunotherapie von Tumoren.
TZM News 1 / 2016 (18 Jg.)
http://www.tumorzentrum-muenchen.de/fileadmin/Downloads/TZM_News/TZMNews_0116_HO.pdf
2015
49. Kobold S, Duewell P, Schnurr M, Subklewe M, Rothenfusser S, Endres S.
Immunotherapie von Tumoren. Aktivierte T-Zellen als gemeinsame Endstrecke neu zugelassener Therapien.
Deutsches Ärzteblatt International 2015; 112:809-15
JIF 3,6
http://www.aerzteblatt.de/treffer?mode=x&wo=16&typ=16&aid=173073&s=Kobold
Immunotherapy in tumors. Activated T cells as a new treatment modality.
Deutsches Ärzteblatt International 2015; 112:809-15
JIF 3,6
http://www.ncbi.nlm.nih.gov/pubmed/26667979
48. Schnurr M, Düwell P, Bauer C, Rothenfusser S, Lauber K, Endres S, Kobold S.
Strategies to relieve immunosuppression in pancreatic cancer.
Immunotherapy 2015; 7:363-76
JIF 2,4
2014
Therapy and prevention of infectious diseases
Drug Research 2014; 64 Suppl 1:S1.
46. Kobold S, Wiedemann G, Rothenfusser S, Endres S.
Modes of action of TLR7 agonists in cancer therapy.
Immunotherapy 2014; 6:1085-95
JIF 2.4
2013
45. Lichtenegger FS, Schnorfeil FM, Hiddemann W, Subklewe M.
Current strategies in immunotherapy for acute myeloid leukemia.
Immunotherapy 2013; 5, 63–78.
2012
44. Endres S, Meuer S, Scriba PC.
Klinische Immunintervention: aktuelle und künftige Ansätze
Arzneimittelforschung 2012; Volume 62.
43. Hotz C, Bourquin C.
Systemic cancer immunotherapy with Toll-like receptor 7 agonists: Timing is everything.
Oncoimmunology 2012; 1:227-228.
43. Merk M, Mitchell R, Endres S, Bucala R.
D-Dopachrome tautomerase (D-DT or MIF-2): Doubling the MIF cytokine family.
Cytokine 2012; 59:10-7.
2011
42. Schmidt A, Endres S, Rothenfusser S.
Viral nucleic acid pattern recognition by RIG-I-like helicases.
Journal of Molecular Medicine 2010; 89:5-12
2006
41. Bourquin C, Voelkl A, Endres S.
Toll-like receptor-7 ligands for the tumor therapy.
Arzneimittel-Forschung Drug Research 2006; 16
40. Endres S, Schreiber S, Beck S, Hartmann G, Bourquin C.
Toll-like receptor-9 ligands in tumor models.
Arzneimittel-Forschung Drug Research 2006; 14-15
2004
39. Lungstras-Bufler K, Bufler P,Abdullah R, Rutherford C, Endres S, Abraham E, Dinarello C, Rodriguez R.
High cytokine levels at admission are associated with fatal outcome in patients with necrotizing fasciitis.
European Cytokine Network 2004; 15:135-38
2003
38. Dugas M, Weinzierl S, Pecar A, Endres S, Hasford J.
Design and implementation of a common drug information database for a university hospital.
Pharmacy World Science 2003; 25:156-161
37. Endres S, Hartmann G.
Therapeutische Oligonukleotide.
Deutsches Ärzteblatt 2003; 47:2577-82
36. Rothenfusser S, Tuma E, Wagner M, Endres S, Hartmann G.
Recent advances in immunostimulatory CpG-oligonucleotides.
Current Opinions in Microbiology 2003; 5
35. Eigler A, Eigenbrod S, Endres S.
Medikamentös induzierte Pankreatitis.
Deutsche Medizinische Wochenschrift 2003; 128:1-4
34. Lorenz R, Endres S.
Diagnosis and treatment of acute hepatitis C.
UpToDate (on-line textbook) 2003;
2002
33. Rothenfusser S, Tuma E, Endres S, Hartmann G.
Plamacytoid dendritic cells: The key to CpG.
Human Immunology 2002; 63:1111-9
32. Schnurr M, Galambos P, Scholz C, Dauer M, Krug A, Hartmann G, Eigler A, Endres S.
Dendritische Zellen - Träger tumorgerichteter Immuntherapie.
Deutsches Ärzteblatt 2002; 37:2408-16
2001
31. Endres S, Buchardi C, Angstwurm M.
Diagnosespektrum in einer internistischen Notaufnahme.
Der Internist 2001; 42:1462-4
30. Kirchgeorg M, Endres S.
Patienten suchen und finden Gesundheitsinformationen im Internet.
Hessisches Ärzteblatt 2001; 9:437-41
29. Eigler A, Loher F, Endres S.
Suppression der Synthese des Tumornekrosefaktors.
Der Internist 2001; 1:28-34
28. Rothenfußer S, Jahrsdörfer B, Krug A, Endres S, Hartmann G.
CpG-Oligonukleotide: Therapie mit bakterieller DNA.
Deutsches Ärzteblatt 2001; 15:981-5
2000
27. Endres S, Siegmund B, Hartmann G, Eigler A.
Pharmakologische Suppression der Synthese von Tumor-Nekrose-Faktor.
Arzneimittel Forschung Drug Research 2000; 50:189-225
1999
26. Schulze J, Endres S.
Genotyp, Phänotyp und unerwünschte Arzneimittelreaktionen.
Arzneimitteltherapie 1999; 17:196-200
25. Endres S, Lorenz R, Loeschke K.
Lipid treatment of inflammatory bowel disease.
Current Opinion in Clinical Nutrition 1999; 2:117-20
1998
24. Hartmann G, Eigler A, Hacker UT, Endres S.
Antisense-Oligonukleotide: Nukleinsäuren zur gezielten Synthesehemmung krankheitsfördernder Proteine.
Deutsches Ärzteblatt 1998; 95:1524-30
1997
23. Hartmann G, Bidlingmaier M, Eigler A, Hacker UT, Endres S.
Cytokines as targets for therapeutic oligonucleotides.
Cytokines, Cellular and Molecular Therapy 1997; 3:247-56
22. Folwaczny C, Endres S..
Fischöl zur Rezidivprophylaxe bei M. Crohn?.
Zeitschrift für Gastroenterologie 1997; 35:651-3
21. Eigler A, Endres S.
Therapie mit Anti-TNF-αntikörper bei Patienten mit Morbus Crohn.
Zeitschrift für Gastroenterologie 1997; 35:899-901
20. Endres S, Eigler A.
Hemmung der NO-Synthase im septischen Schock.
Der Internist 1997; 38:466-9
19. Hartmann G, Krug A, Bidlingmaier M, Eigler A, Endres S.
Antisense strategies for inhibition of tumor necrosis factor-a synthesis.
Nucleosides and Nucleotides 1997; 629-34
18. Eigler A, Sinha B, Hartmann G, Endres S.
Taming TNF: Anti-tumor necrosis factor strategies.
Immunology Today 1997; 18:487-92
1996
17. Drenth JPH, Endres S, Belohradsky BH, van der Meer JWM.
Das Hyper-IgD-Syndrom.
Deutsche Medizinische Wochenschrift 1996; 121:1299-1300
16. Endres S, von Schacky C.
Polyunsaturated fatty acids and human cytokine production.
Current Opinion in Lipidology 1996; 7:48-52
1995
15. Endres S, Sinha B, Eisenhut T.
n-3 Polyunsaturated fatty acids in the regulation of human cytokine synthesis.
Biochemical Society Transactions 1995; 23:277-81
14. Endres S, Sinha B, Eigler A.
Tumor-Nekrose-Faktor: Therapeutische Strategien zu Synthesehemmung und Antagonismus.
Deutsches Ärzteblatt 1995; 92:2185-8
13. Endres S, De Caterina R, Kristensen SD, Schmidt EB.
n-3 Polyunsaturated fatty acids: Update 1995.
European Journal of Clinical Investigation 1995; 25:629-38
1994
12. De Caterina R, Endres S, Kristensen SD, Schmidt EB.
n-3 Fatty acids and renal diseases.
American Journal of Kidney Diseases 1994; 24:397-415
1993
11. Endres S.
Messengers and mediators: the interaction between lipids, eicosanoids and cytokines.
The American Journal of Clinical Nutrition 1993; 57:789-800
10. Markewitz A, Faist E, Weinhold C, Lang S, Endres S, Hültner L, Reichart B.
Alterations of cell-mediated immune response following cardiac surgery.
European Journal of Cardio-thoracic Surgery 1993; 105:15-24
9. Kristensen SD, De Caterina R, Schmidt EB, Endres S.
Fish oil and ischaemic heart disease.
British Heart Journal 1993; 70:212-4
1992
8. Endres S, Gröttrup E.
Interleukin-1-Rezeptor-Antagonist.
Deutsches Ärzteblatt 1992; 89:1952-7
1991
7. Fülle HJ, Endres S, Sinha B, Stoll D, Weber PC, Gerzer R.
Effects of SIN-1 on cytokine synthesis in human mononuclear cells.
Journal of Cardiovascular Pharmacology 1991; 17:113-16
1990
6. Dinarello CA, Endres S, Meydani SN, Meydani M, Hellerstein MK.
Interleukin-1, anorexia and dietary fatty acids.
Annals of the New York Academy of Sciences 1990; 587:332-8
1989
5. Endres S, Hohnloser J.
Therapeutischer Einsatz von Zytokinen.
Münchner Medizinische Wochenschrift 1989; 131:507-9
4. Endres S, van der Meer JWM, Dinarello CA.
Zytokine in der Pathogenese des Fiebers.
Der Internist 1989; 30:358-61
1988
3. Dinarello CA, Endres S.
A role of interleukin-1 in the pathogenesis of hypersensitivity diseases.
Journal of Cellular Biochemistry 1988; 39:229-38
1987
2. Endres S, van der Meer JWM, Dinarello CA.
Interleukin-1 in the pathogenesis of fever.
European Journal of Clinical Investigation 1987; 17:469-74
1983
1. Endres S.
Praktikum der Inneren Medizin in den USA.
Deutsche Medizinische Wochenschrift 1983; 108:1530-3
Letters
3. Oener A, Kobold S.
Transwell migration assay to interrogate human CAR-T cell chemotaxis.
STAR Protocols 2022, 3:101708, JIF 1,3
2. Dauer M, Schad K, Herten J, Endres S, Eigler A.
Author reply to: Dauer M et al. Mature dendritic cells derived from human monocytes within 48 hours: a strategy mimicking dendritic cell differentiation from blood precursors in vivo. Journal of Immunology 2003; 170:4069
Journal of Immunology 2004; 172:3-4
1. Hartmann G, Bidlingmaier M, Jahrsdörfer B, Endres S.
Playground of oligonucleotides: extrapolation from in vitro to in vivo?
Nature Medicine 1997; 3:3
Books
- Endres S.
n-3 Fettsäuren und zyklische Nukleotide in der Regulation der Synthese von Interleukin-1 und Tumor-Nekrose-Faktor.
Habilitationsschrift, LMU München 1992; - De Caterina R, Endres S, Kristensen SD, Schmidt EB, editors.
n-3 Fatty Acids and Vascular Disease.
Springer-Verlag, Berlin - Heidelberg 1993; - Scriba PC, Endres S (Heftherausgeber)
Klinische Forschergruppen in Deutschland.
Der Internist 1995; 36(4) - Kristensen SD, Schmidt EB, De Caterina R, Endres S, editors.
Preventive Strategies in Vascular Disease: Focus on n-3 Fatty Acids.
Springer-Verlag, Berlin - Heidelberg 1995; - Scriba PC, Endres S (Heftherausgeber).
Klinische Pharmakologie: Therapie mit und gegen NO.
Der Internist 1997; 38(5) - Hartmann G, Endres S, editors.
Manual of Antisense Methodology.
Kluwer Academic Publishers, Boston 1999; - Werdan K., Endres S (Heftherausgeber).
Zytokine und (Anti-)Zytokintherapie.
Der Internist 2001; 42(1) - Scriba PC, Endres S (Wissenschaftliche Leitung).
Perspektiven der gastroenterologischen Pharmakotherapie
Arzneimittel-Forschung Drug Research 2002; 52(12) - Endres S, Scriba PC (Heftherausgeber).
Pharmakotherapie in der Gastroenterologie
Deutsche Medizinische Wochenschrift 2003; 8 - Endres S (Herausgeber).
Facharztprüfung Innere Medizin in Fällen, Fragen und Antworten
Urban & Fischer 2003; - Ruß A, Endres S, Hoffmann C (Herausgeber).
Arzneimittel manual.
Börm Bruckmeier Verlag, Grünwald 2005; - Hartmann G, Endres S (Heftherausgeber).
Toll-like receptor-based drug development.
Arzneimittel-Forschung Drug Research 2006; - Schmitz G, Endres S, GötteD (Herausgeber).
Biomarker: Bedeutung für medizinischen Fortschritt und Nutzenbewertung
Schattauer Verlag, Stuttgart, 2008;
Book Chapters
- Endres S, Ghorbani R, Cannon JG, Lonnemann G, van der Meer JWM, Wolff SM, Dinarello CA.
Humans taking dietary omega-3 fatty acids have decreased in vitro production of interleukin-1. In: Powanda MC, et al., editors.
Monokines and Other Non‑Lymphocytic Cytokine
Alan R. Liss, New York 1988; 153-8 - Cannon JG, van der Meer JWM, Endres S, Lonnemann G, DinarelloCA.
Interleukin‑1 in human blood: Chloroform extraction and radioimmunoassay. In: Powanda MC, et al., editors.
Monokines and Other Non‑Lymphocytic Cytokine
Alan R. Liss, New York 1988; 373‑6 - Dinarello CA, Endres S.
Interleukin-1. In: Groopman JE, et al., editors.
Mechanisms of Action and Therapeutic Applications of Biologicals in Cancer and Immune Deficiency Disorders
Alan R. Liss, New York 1989; 201-18 - Endres S, Dinarello CA.
Interleukin‑1 and tumor necrosis factor - mediators of the acute phase response and possible modes for their manipulation. In: Zor U, et al., editors.
Leukotrienes and Prostanoids in Health and Disease. New Trends in Lipid Mediator Research
Karger, Basel 1989; (3)114-8 - Shapiro AC, Meydani SN, Meydani M, Morrow F, Blumberg J, Endres S, Dinarello CA.
The effect of fish oil supplementation on plasma alpha‑tocopherol and retinol levels. In: Chandra RK, editor.
Health Effects of Fish and Fish Oils
ARTS Biomedical Publishers, St. John's, Newfoundland 1989; 537-46 - Endres S, Meydani SN, Ghorbani R, Schindler R, Dempsey R, Dinarello CA.
Interleukin-2 production is suppressed by dietary n-3 fatty acids but enhanced by oral aspirin. In: Dinarello CA, et al., editors.
Physiological and Pathophysiological Effects of Cytokines
Alan R. Liss, New York 1990; 281-6 - Nerad JL, Griffiths JK, van der Meer JWM, Endres S, Keusch GT, Bennish M, Dinarello CA, Cannon JG.
A simple rapid method for studying cytokine production by endotoxin-stimulated leukocytes. In: Dinarello CA, et al., editors.
Physiological and Pathophysiological Effects of Cytokines
Alan R. Liss, New York 1990; 19-24 - Meydani SN, Endres S, Woods MM, Goldin BR, Soo C, Morrill-Labrode A, Dinarello CA, Gorbach SL.
Effect of oral n-3 fatty acid supplementation on the immune response of young and older women. In: Samuelsson B, et al., editors.
Advances in Prostaglandin, Thromboxane, and Leukotriene Research
Raven Press, New York 1990; (21)245-8 - Endres S, Meydani SN, Dinarello CA.
Effects of w-3 fatty acid supplements on ex vivo synthesis of cytokines in human volunteers. Comparison with oral aspirin and ibuprofen. In: Simopoulos AP, et al., editors.
World Rev Nutr Diet
Karger, Basel 1991; (66)401-6 - Endres S, Kaminski W, von Schacky C.
n-3 Fatty acids and the regulation of growth factors and cytokines. In: Frölich JC, von Schacky C, editors.
Clinical Pharmacology
Zuckschwerdt, München 1992; (5)98-103 - Endres S.
Cytokines and their modulation by n-3 fatty acids with regard to atherogenesis. In: De Caterina R, Kristensen SD, Schmidt EB, editors.
Fish Oil and Vascular Disease
Springer-Verlag, Berlin 1992; 59-64 - Endres S, Meydani SN, Dinarello CA.
Manipulation of cytokine synthesis through dietary lipids. In: Faist E, et al., editors.
Proceedings of the Second International Congress on the Immune Consequences of Trauma, Shock and Sepsis
Springer-Verlag, Berlin 1993; 1013-6 - Endres S, Fülle HJ, Sinha B, Stoll D, Gerzer R.
Regulation of cytokine synthesis through cyclic nucleotides. In: Faist E, et al., editors.
Proceedings of the Second International Congress on the Immune Consequences of Trauma, Shock and Sepsis
Springer-Verlag, Berlin 1993; 609-12 - Endres S, Eisenhut T, Sinha B.
n-3 fatty acids and cytokines. In: De Caterina R, Endres S, Kristensen SD, Schmidt EB, editors.
n-3 Fatty Acids and Vascular Disease
Springer-Verlag, Berlin - Heidelberg 1993; 31-8 - Endres S, Sinha B, Eisenhut T.
w3 fatty acids in the regulation of cytokine synthesis. In: Galli C, Simoupolous AP, Tremoli E, editors.
Effects of Fatty Acids and Lipids in Health and Disease. World Rev Nutr Diet
Karger-Verlag, Basel 1994; (76)143-5 - Endres S, Eisenhut T, Sinha B.
Omega-3 fatty acids in the regulation of cytokine synthesis. In: Pownall HJ, Spector AA, Conference Cochairs.
Proceedings from the Scientific Conference on Omega-3 Fatty Acids in Nutrition, Vascular Biology, and Medicine
American Heart Association 1995; 146-151 - Endres S, Gröttrup-Wolfers E, Lorenz R, Loeschke K.
n-3 Fatty acids in inflammatory bowel disease. In: Kristensen SD, Schmidt EB, De Caterina R, Endres S, editors.
n-3 Fatty Acids: Prevention and Treatment in Vascular Disease
Springer-Verlag, Berlin - Heidelberg 1995; 181-8 - Endres S, Eigler A, Hartmann G.
n-3 Polyunsaturated fatty acids and human cytokine synthese. In: Yehuda S, Mostofsky DI, editors.
n-3 Fatty Acids: Biochemistry and Behavior
Human Press Inc., Totowa, NJ, USA 1999; 609-18f - Endres S
Gastroenterologie. In: Endres S, editor.
Facharztprüfung Innere Medizin.
Urban & Fischer-Elsevier, München 2003; 137-219 - Bourquin C, Anz D, Rothenfußer S, Endres S.
Toll-like-Rezeptoren als neue Marker und Targets der Pharmakotherapie: Schmitz G, Endres S, Götte D, editors.
Biomarker: Bedeutung für medizinischen Fortschritt und Nutzenbewertung.
Schattauer, Stuttgart, New York, 2008; 75-86 - Endres S, Anz D, Bourquin C.
Biomarker: Anwendung in der Praxis-Beispiel Gastroenterologie. In: Schmitz G, Endres S, Götte D, editors.
Biomarker: Bedeutung für medizinischen Fortschritt und Nutzenbewertung.
Schattauer, Stuttgart, New York, 2008; 115-118 - Endres S, Kobold S.
Budenosid: Pharmakologische Grundlagen. In: Miehlke S, Madisch A, editors.
Topische Steroide in der Gastroenterologie.
UNI-MED Verlag AG, Bremen, London, Boston, 2013; 12-15
Book of the Year

Authors: Andreas Ruß, Stefan Endres

Urban & Fischer, aktualisierte Auflage (2022), www.elsevier.de
Endres S. Klinikum der Universität München, Medizinische Klinik Innenstadt

Boston, 2000
Editors: Hartmann G., Endres S., University of Munich
Talks
2015
93. S. Endres "Immuntherapie von Tumoren".
81st Annual Congress of the German Society for Experimental and Clinical Pharmacology Christian-Albrechts-Universität zu Kiel, 10. bis 12. März 2015
2014
92. S. Endres „Toll-like-receptor 7 agonist and RIG-I-ligands for tumorimmunotherapy".
ITOC-1-Konferenz (Immunotherapy of cancer) Klinikum rechts der Isar, 12. bis 14. März 2014
91. S. Endres "Translational approach to Research at the LMU".
Interim Evaluation, HelMA "Mental Health in an Ageing Society" Helmholtz Zentrum München, 9. Februar 2011
2011
90. S. Endres "Strategieworkshop Spitzencluster m4".
Posiumsdiskussion "Vernetzung des Spitzenclusters in München und außerhalb der Region" MPI für Biochemie, Martinsried, 15. Februar 2011
89. S. Endres "Translational approach to Research at the LMU".
Interim Evaluation, HelMA "Mental Health in an Ageing Society" Helmholtz Zentrum München, 9. Februar 2011
88. S. Endres "RIG I like helicases as targets for immunotherapy".
Wissenschaftliches Meeting, Genzentrum München-BioM Biotech Cluster Development GmbH, Schloss Ringberg, 4. bis 5. Januar 2011
2010
87. S. Endres "Immunostimulatory RNA Oligonucleotides".
CIPS-M-Wildbad Kreuth-Konferenz Epigenetik und Protein-Nukleinsäure-Interaktion, Wildbad Kreuth, 27. bis 29. September 2010
86. S. Endres "Activating NK cells and inhibiting tregs by RNA oligonucleotides".
8th World Congress on Trauma, Shock, Inflammation and Sepsis - TSIS 2010, München, 9. bis 13. März 2010
85. S. Endres "Therapie und Prävention: Pro-Inflammatorisch - Induktion eines zytotoxischen Milieus".
29. Deutscher Krebskongress, Stukturen verändern, Heilung verbessern, Berlin, 24. bis 27. Februar 2010
84. S. Endres "A model for Transcription initiation for the immunotherapie of cancer".
Wissenschaftliches Meeting, Genzentrum München-BioM Biotech Cluster Development GmbH, Schloss Ringberg, 4. bis 6. Januar 2010
2009
83. S. Endres "Anti-tumor activity of immunostimulatory RNA oligonucleotide".
CIPS-M-Kloster Irsee-Konferenz, Epigenetik und Protein-Nukleinsäure-Interaktionen, Kloster Irsee, 11. bis 13. Oktober 2009
82. S. Endres "Therapeutische Zielstrukturen des angeborenen Immunsystems".
Symposium Workshop IGLD-Interdisziplinäre Gruppe für Labor und Durchflusszytometrie, München, 12. bis 14. März 2009
81. S. Endres "Forschungsstrategien der Medizinischen Fakultät".
Zweite Klausurtagung der Forschungskommission der Medizinischen Fakultät der Ludwig-Maximilians-Universität München, Bad Bayersoien, 13. bis 14. Februar 2009
2008
80. S. Endres "In vivo anti-tumor activity of immunostimulatory RNA oligonucleotides".
CIPS-M-Elmau-Konferenz, Epigenetik und Protein-Nukleinsäure-Interaktionen, Elmau, 15. bis 16. September 2008
2007
79. S. Endres "Toll-like-Rezeptoren als neue Marker und Targets der Pharmakotherapie"
Symposium-Novartis-Stiftung für therapeutische Forschung, Bedeutung von Biomarkern für medizinischen Fortschritt und Nutzenbewertung, Nürnberg, 29. bis 30. Juni 2007
78. S. Endres "Inducing T cell and B cell responses with immunostimulatory RNA".
Collaborative Research Centres 456 and 576, International Workshop: Toll-like receptors and beyond, Seeon, 18. bis 21. März
77. S. Endres "Inducing T cell and B cell responses with immunostimulatory RNA".
Trauma, shock, inflammation and sepsis - TSIS 2007, München, 13. bis 17. März 2007
2006
76. S. Endres "Vorsitz "Neue Arzneimittel in der Gastroenterologie." und Vortrag „Toll-like Rezeptor-Liganden als Vakzine Adjuvans."
61. Jahrestagung der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten (DGVS), Hannover, 13. bis 16. September 2006
75. S. Endres "Immunstimulatorische Oligonukleotide"
Viertes Statusseminar des Promotionsstudienganges „Molekulare Medizin und Systembiologie“ (Leiter: Prof. Dr. Dr. J. Heesemann), Herrsching, 19. bis 21. Mai 2006
74. S. Endres "Pharmakogenetik: Was ist relevant für den Internisten?"
XXXI. Wissenschaftlicher Kongress, Berufsverband Deutscher Krankenhausapotheker (ADKA), Trier, 12. bis 13. Mai 2006
73. S. Endres "Therapeutic oligonucleotides: from antisense to isRNA."
Vortrag im Rahmen des Graduiertenkollegs 1202 „Oligonukleotide in Zellbiologie und Therapie“, München, 20. Februar 2006
72. S. Endres "Arzneimitteltherapie im Alter"
Podiumsveranstaltung des Gesundheitsforums der Süddeutschen Zeitung e. V., München, 14. Februar 2006
71. S. Endres "Zukunftskonzept Klinische Pharmakologie am Dr. Margarete Fischer-Bosch-Institut Stuttgart."
Besuchsdelegation der Berufungskommission, München, 25. Januar 2006
70. S. Endres "Immunstimulatorische Oligonukleotide"
Forschungsseminar im Arbeitskreis Nanomedizin, Center for NanoScience LMU München (Prof. Dr. J. Rädler), München, 11. Januar 2006
2005
69. S. Endres "Therapeutische Oligonukleotide"
Berufungskommission W3-Professur für Klinische Pharmakologie, Tübingen, 17. November 2005
68. S. Endres "CpG-Oligonukleotide als Vakzine-Adjuvans in der Immuntherapie von Tumoren."
Wissenschaftlicher Nachmittag: Vakzine als Tumortherapie. Chirurgische Klinik Großhadern (Direktor Prof. Dr. K.-W. Jauch), Klinikum der Universität München, München, 12. Januar 2005
2004
67. S. Endres "Small interfering RNA (siRNA) und andere Oligonukleotide als neues Prinzip in der Regulation der Genexpression."
Kongress für Klinische Chemie und Laboratoriumsmedizin, Düsseldorf, 22. bis 24. November 2004
66. S. Endres "Kombination von dendritischer-zell-basierter Immuntherapie mit Chemotherapie in der Behandlung experimenteller gastrointestinaler Tumore."
59. Tagung der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten (DGVS) 2004, Leipzig, 1. bis 4. September 2004
65. S. Endres "Phosphodiesterasehemmung als antiinflammatorisches Prinzip bei CED?"
59. Tagung der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten (DGVS) 2004, Leipzig, 1. bis 4. September 2004
64. S. Endres "Necrotic death mediators including ATP and adenosine signal in DCs."
In Symposium: Biology and therapeutic application of dendritic cells in chronic inflammation. 6th World Congress on Trauma, Shock, Inflammation and Sepsis, München, 2. bis 6. März 2004
63. S. Endres "Expertengespräch zum geplanten Förderschwerpunkt „Innovative Therapieverfahren“ des Bundesministeriums für Bildung und Forschung (BMBF)."
Bonn, 16. Februar 2004
62. S. Endres "Dendritische Zellen und immunstimulatorische Oligonukleotide zur Therapie experimenteller gastrointestinaler Tumore."
Forschungsseminar; Charitè Universitätsmedizin Berlin, Campus Virchow, Klinik für Gastroenterologie (Direktor: Prof. Dr. B. Wiedenmann), Berlin, 12. Januar 2004
2003
61. S. Endres "Dendritische Zellen und immunstimulatorische Oligonukleotide im Maustumormodell (Colon-26)."
Forschungsseminar; Chirurgische Klinik Großhadern, Klinikum der Universität München (Direktor: Prof. Dr. K.-W. Jauch), München, 2. Dezember 2003
60. S. Endres "Immuntherapie gastrointestinaler Tumoren mit dendritischen Zellen."
Forschungsforum 2: Moderne und zukünftige Therapiekonzepte in der Gastroenterologie (Vorsitz: Prof. Dr. M. Lerch und Prof. Dr. R.M. Schmid); 58. Tagung der DGVS, Nürnberg, 17. bis 20. September 2003
59. S. Endres "The use of CpG oligonucleotides for immunotherapy of cancer."
Workshop der Paul-Martini-Stiftung: "Therapeutic oligonucleotides in drug development", Berlin-Brandenburgische Akademie der Wissenschaften in Berlin, (Organisation: Prof. Dr. Stefan Endres, PD Dr. Gunther Hartmann, Dr. Klaus-Dieter Langner), Berlin, 13. und 14. Juni 2003
2002
58. S. Endres "TNF-a-Blockade: Eine Standortbestimmung."
Update chronische entzündliche Darmerkrankungen, Gastroenterologische Fortbildung, Klinikum der Universität München, Medizinische Poliklinik Innenstadt, (Direktor: Prof. Dr. D. Schlöndorff), München, 11. Dezember 2002
57. S. Endres "Dendritic cells and CpG oligonucleotides in murine tumor models."
International Symposium "Defense Mechanism in Tumor Growth and Infection", (Organisation: Prof. Dr. M. Krönke), Zentrum für Molekulare Medizin der Universität zu Köln, Köln, 23. und 24. November 2002
56. S. Endres "The use of CpG oligonucleotides for immunotherapy of cancer."
Symposium der Paul-Martini-Stiftung in Verbindung mit der Akademie der Wissenschaften und der Literatur, (Organisation: Prof. Dr. Dr. P. C. Scriba, Prof. Dr. S. Endres), Mainz, 13. bis 16. November 2002
55. S. Endres "Immuntherapie mit dendritischen Zellen."
Medizinische Klinik II, (Direktor: Prof. Dr. B. Göke), Klinikum Großhadern der LMU München, München, 30. Oktober 2002
54. S. Endres "Nebenwirkungen von Medikamenten Arzneimittelsicherheit."
Gesundheitsforum der Süddeutschen Zeitung e. V., (Organisation: Prof. Dr. W. Eisenmenger), Walter-Straub-Institut, München, 15. Oktober 2002
53. S. Endres "Zelluläre Immuntherapie des Pankreaskarzinoms: Induktion einer Tumorantigen-spezifischen zytotoxischen T-Zell-Antwort durch Transfektion dendritischer Zellen mit Tumorzell-RNA."
Kommission für Forschung und Lehre, (Vorsitzender: Prof. Dr. J. Heesemann), Medizinische Fakultät der Ludwig-Maximilians-Universität, München, 4. Oktober 2002
52. S. Endres "Combined dendritic cell- and CpG oligonucleotide-based immune therapy cures large murine tumors which resist chemotherapy."
International Symposium on Dendritic Cells, (Organisation: Prof. Dr. G. Schuler), Bamberg, 19. bis 24. September 2002
51. S. Endres "Dendritische Zell-basierte Vakzine gegen Tumore aus Kolonkarzinomzellen in der Maus."
Arbeitsgruppe Immuntherapie gastrointestinaler Tumoren mit dendritischen Zellen, (Organisation: Prof. Dr. S. Endres, Prof. Dr. I. Schmidt-Wolf), Tagung der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten, Bonn, 11. bis 14. September 2002
50. S. Endres "Combined dendritic cell- and CpG oligonucleotide-based immune therapy cures large murine tumors which resist chemotherapy."
Tegernsee Conference on Immunotherapy of Solid Cancer (Organisation: Prof. Dr. B. Fox, Seattle), Rottach-Egern, 3. bis 5. Juni 2002
2001
49. S. Endres "Dendritische-Zell-basierte Vakzine im Tiermodell kolorektaler Tumore."
Klinik für Dermatologie und Allergologie, Klinikum der Universiät, München, 24. Oktober 2001
48. S. Endres "Möglichkeiten der pharmakologischen Hemmung von TNF-α."
Immunologie-Tag Bern, Inselspital der Universität, Bern, 20. September 2001
2000
47. S. Endres "Anti-TNF-α Therapie: Pharmakologische Strategien."
Symposium Stellenwert der Anti-Zytokin-Therapie in Gastroenterologie und Rheumatologie. Medizinische Poliklinik Innenstadt, Klinikum der Universität, München, 23. September 2000
46. S. Endres "Das Zytokin Tumor-Nekrose-Faktor: Achillesferse der Entzündung."
Jahreskongress für Klinische Pharmakologie 2001, Deutsche Gesellschaft für Klinische Pharmakologie, Berlin, 5. Oktober 2000
45. S. Endres "Anti-Tumor-Nekrose-Faktor-Therapien."
Symposium: Oligonukleotide, Einsatz in Forschung und Therapie. Graduiertenkolleg Biochemische Pharmakologie der Universität Konstanz, Konstanz, 14. Juli 2000
44. S. Endres "Pharmacological suppression TNF-α synthesis."
5th International Congress on The Immune Consequences of Trauma, Shock, Inflammation and Sepsis, Ludwig-Maximilians-Universität, München, Kliniken Großhadern, 1. bis 4. März 2000
1999
43. S. Endres "Pharmakologische Suppression der Synthese von Tumor-Nekrose-Faktor."
Vortrag und Vorsitz der Sitzung. Immunsuppression u2013 Domäne der Pharmakotherapie bei Autoimmunerkrankung und Transplantation. Symposium der Paul-Martini-Stiftung; in Verbindung mit der Akademie der Wissenschaften, Mainz, 12.und 13. November 1999
42. S. Endres "Tumor-Nekrose-Faktor."
Margarete-Fischer-Bosch Institut für Klinische Pharmakologie (Direktor Prof. Dr. Eichelbaum), Stuttgart, 21.Oktober 1999
41. S. Endres "Das Zytokin Tumor-Nekrose-Faktor: Achillesferse der Entzündung."
70. Treffen des Heinz-Breuer-Diskussionkreises für Stoffwechsel und Endokrinologie, Festsaal Redoute, Bonn-Bad Godesberg, 18. Juni 1999
40. S. Endres "Antisense-Oligonukleotide: Chancen und Grenzen."
Jahreskongress für Klinische Pharmakologie 2000, Deutsche Gesellschaft für Klinische Pharmakologie, Berlin, 10. bis 12. Juni 1999
39. S. Endres "Antisense-Therapie : Wo stehen wir?"
Symposium: Oligonukleotide, Einsatz in Forschung und Therapie. Graduiertenkolleg der Universität Ulm, Ulm, 18. April 1999
1998
38. S. Endres "Cachectin/Tumor-Nekrose-Faktor: Bindeglied von Stoffwechsel und Immunsystem."
Stoffwechselabend internistische Kliniken München. Medizinische Klinik Innenstadt, München, 3. November 1998
37. S. Endres "Darmbakterien und Zytokinantwort."
Fortbildungstagung Chronisch-entzündliche Darmerkrankungen fokussiert. Medizinische Klinik Innenstadt, München, 17. Juni 1998
1997
36. S. Endres "Regulation of TNF-synthesis by PDE4 inhibitors."
FASEB summer conference "Cytokines and Lipid Modulators", Syxton River, Vermont, USA, 7. bis12. Juni 1997
35. S. Endres "Pharmacological strategies to suppress TNF-α synthesis."
4th International Congress on The Immune Consequences of Trauma, Shock and Sepsis, Ludwig-Maximilians-Universität, München, Klinikum Großhadern, 4. bis 8. März 1997
1996
34. S. Endres "Infektiöse Colitiden."
Coloskopie-Seminar des Bereichs Gastroenterologie, Klinikum Innenstadt der Ludwig-Maximilians-Universität, München, 9. November 1996
33. S. Endres "Antagonismus von Tumor-Nekrose-Faktor: Therapeutische Strategien."
16. Bayrisches Chemotherapie-Expertengespräch (Prof. Dr. W. Marget), Murnau, 5. Juli 1996
32. S. Endres "Antagonismus von: Therapeutische Strategien."
Berufungsausschuss der Medizinischen Fakultät der Technischen Universität (Prof. Dr. Dr. M. Classen), München, 25. Juli 1996
31. S. Endres "Sepsis: Das Problem der generalisierten Entzündung."
Symposiumsvorsitz, 102. Tagung der Deutschen Gesellschaft für Innere Medizin, Wiesbaden, 16. April 1996
1995
30. S. Endres "FACS analysis of intracellular cytokines."
Workshop: Measurement of TNF levels in body fluids and stimulated cultures. Evaluation of methodology for phase I and II trials. Schering AG, Berlin, 29. Juni 1995
29. S. Endres "n-3 Fatty acids for prevention of recurrence of ulcerative colitis."
4th United European Gastroenterology Week, Berlin, 16. September 1995
28. S. Endres "Antagonismus von Tumor-Nekrose-Faktor: Therapeutische Strategien."
Symposium 20 Jahre Wilhelm Sander Stiftung, München, 27. November 1995
27. S. Endres "Antagonismus von Tumor-Nekrose-Faktor: Therapeutische Strategien."
Berufungsausschuß der Westfälischen Wilhelms-Universität, Münster, 5. Juli 1995
26. S. Endres "n-3 fatty acids and cytokines".
2nd Congress of the International Society for the Study of Fatty Acids and Lipids, Betheseda, 7. bis 10. Juni 1995
25. S. Endres "n-3 fatty acids in inflammatory bowel disease."
Annual meeting of the European Society of Clinical Investigation, Cambridge, 5. April 1995
1994
24. S. Endres "n-3 Polyunsaturated fatty acids in the regulation of human cytokine synthesis."
British Biochemical Society Meeting, The University of Sussex, Brighton, 13. bis 16. Dezember 1994
23. S. Endres "Tumor-Nekrose-Faktor in der Pathogenese des septischen Schocks".
Universitäts-Krankenhaus Eppendorf, Kernklinik (Prof. Dr. H. Greten); Berufungsausschuss des Fachbereichsrats, Hamburg, 11. November 1994
22. S. Endres "Modulation of tumor necrosis factor synthesis by inhibitors of phosphodiesterases."
3rd International Congress on the Immune Consequences of Trauma, Shock and Sepsis, München, 2. bis 5. März 1994
21. S. Endres "n-3 Fettsäuren und zyklische Nukleotide in der Regulation der Synthese von Interleukin-1 und Tumor-Nekrose-Faktor."
Universitätsklinikum Rudolf Virchow der Freien Universität, Abteilung für Innere Medizin, Schwerpunkt Nephrologie und Internistische Intensivmedizin (Prof. Dr. U. Frei), Berlin, 18. Februar 1994
20. S. Endres "n-3 ungesättigte Fettsäuren und cAMP in der Regulation der Synthese von Interleukin-1 und Tumor-Nekrose-Faktor."
Deutsches Krebsforschungszentrum (DKFZ, Prof. Dr. S. Meuer), Heidelberg, 20. Januar 1994
1993
19. S. Endres "n-3 ungesättigte Fettsäuren und cAMP in der Regulation der Synthese von Interleukin-1 und Tumor-Nekrose-Faktor."
Firma Cassella, Frankfurt am Main, 10. Dezember 1993
18. S. Endres "Polyunsaturated fatty acids - Effects on the immune system and on immunologically mediated diseases"
Joint Consultation of Food and Agriculture Organisation (FAO) and World Health Organisation (WHO) on Fats and Oils in Human Nutrition. Rom, 22. Oktober 1993
17. S. Endres "n-3 fatty acids and in the regulation of cytokine synthesis."
1rst International Congress of the International Society for the Study of Fatty Acids and Lipids. Lugano, 30. Juni 1993
16. S. Endres "n-3 fatty acids and cytokines."
27th Annual Scientific Meeting of the European Society of Clinical Investigation. Heidelberg, 16. April 1993
1992
15. S. Endres "Tumor-Nekrose-Faktor in der Pathogenese der Malaria tropica".
Habiliationsvortrag, Fakultät der Ludwig-Maximilians-Universität München, 9. Dezember 1992
14. S. Endres "Messengers and mediators: the interaction between lipids, eicosanoids and cytokines."
1rst Maastricht Seminar on Health Sciences; Rijksuniversiteit Limburg. Maastricht, 13. Februar 1992
13. S. Endres "n-3 fatty acids and cyclic nucleotides in the regulation of the synthesis of interleukin-1 and tumor necrosis factor"
Cytokines in Cell Signalling (Prof. Dr. Meßmer). 3rd Walter-Brendel-Symposium, Axams, 2. bis 6. Februar 1992
1991
12. S. Endres "Cytokines u2013 influence on heart function and myocardial metabolism."
Workshop: Cellular aspects of impaired heart function. Wuppertal, 29. November 1991
11. S. Endres "Zyklische Nukleotide in der Regulation der Synthese von Zytokinen"
Institut für Pharmakologie (Prof. Dr. Resch); Medizinische Hochschule Hannover, 1. November 1991
10. S. Endres "n-3 Fettsäuren und zyklische Nukleotide in der Regulation der Synthese von Interleukin-1 und Tumor-Nekrose-Faktor."
Fakultätskolloquium der Ludwig-Maximilians-Universität München, 10. Juli 1991
9. S. Endres "Cytokines and their modulation with n-3 fatty acids with regard to atherogenesis."
25th Annual Scientific Meeting of the European Society of Clinical Investigation. Pisa, 4. April 1991
1990
8. S. Endres "Tumor-Nekrose-Faktor."
Kolloquium der Medizinischen Klinik des Klinikums Innenstadt der Universität München, 11. Dezember 1990
7. S. Endres "Regulation der Synthese von Interleukin-1 und Tumor Nekrose Faktor."
Forschungsinstitut Borstel (Prof. Dr. Flad), 9. Januar 1990
1989
6. S. Endres "Oral polyunsaturated n-3 fatty acids suppress the synthesis of interleukin-1 and tumor necrosis factor by human mononuclear cells."
Commission of the European Communities. Workshop: The Biology of Cytokines in Cancer. Leuven, 6.-8. September 1989
5. S. Endres "The effect of dietary supplementation with fish oil on the synthesis of interleukin-1 and tumor necrosis factor."
Universität Nijmegen, 24. Februar 1989
1988
4. S. Endres "Interleukin‑1 und andere Zytokine bei der Genese der Atherosklerose."
Symposium "Prävention und Therapie der Atherosklerose", München, 3. Dezember 1988
3. S. Endres "Entwicklung und Anwendung von Radioimmunoassays für Interleukin‑1 und Tumor Nekrose Faktor."
Deutsches Krebsforschungszentrum (Prof. Dr. Kirchner), Heidelberg, 14. Juni 1988
1987
2. S. Endres "Effects of dietary omega‑3 fatty acids on the in vitro production of human interleukin‑1."
International Workshop on Monokines and Other Non-Lymphocytic Cytokines, Hilton Head Island, South Carolina, 6. bis 10. Dez. 1987
1. S. Endres "Use of a highly sensitive radioimmunoassay for measuring intraindividual variation of human monocyte interleukin‑1b production."
International Conference on Tumor Necrosis Factor and Related Cytokines, Heidelberg, 14. bis 18. Sept. 1987