i-Target 2.0 IOLIN seminar program
Location and Time
Results colloquium or educational colloquium: Monday, 17:00 to 18:00
Journal club: Monday, 18:00 to 18:30
Summer semester 2024
30. September 2024
Results colloquium
Journal club
Speaker
Giulia Rappa, AG Sublewke
Vivien Menkhoff, AG Kobold
Topic
n.a.
n. a.
23. September 2024
Results colloquium
Journal club
Speaker
Dr. Thu Nguyen, AG Kobold
Tanja Maier, AG Kroiß
Topic
n.a.
n. a.
16. September 2024
Results colloquium
Journal club
Speaker
Linda Hammann, AG Anz
Valerie Kolarik, AG König Schnurr
Topic
n.a.
n. a.
22. July 2024
Results colloquium
Journal club
Speaker
Monika Sponheimer, AG Sublewke
Mara Henrich, AG Kobold
Topic
n.a.
n. a.
15. July 2024
Results colloquium
Journal club
Speaker
Charlotte Carcopino, AG Kobold
Shenzhi Jia, AG Rothenfußer
Topic
n.a.
n. a.
8. July 2024
Results colloquium
Journal club
Speaker
Till Johannsmann, AG Daniel
Jan Gärtig, AG Anz
Topic
n.a.
n. a.
1. July 2024
Results colloquium
Journal club
Speaker
Emre Erdogan, AG Kobold
Giulia Rappa, AG Subklewe
Topic
n.a.
n. a.
24. June 2024
Guest speaker
Speaker
Rhich Enmon
Topic
Patent Attorney
17. June 2024
Results colloquium
Journal club
Speaker
Sandra Dirschl, AG Daniel
Adriano Carboniero, AG Teurich
Topic
n.a.
n. a.
10. June 2024
Guest speaker
Speaker
Dr. Sustmann
Topic
n.a.
3. June 2024
Results colloquium
Journal club
Speaker
Dr. Marcel Trefny, AG Kobold
Emanuele Carlini, AG Kobold
Topic
n.a.
n. a.
27. May 2024
Results colloquium
Journal club
Speaker
Valerie Kolarik, AG König / Schnurr
Alejandro Salinas, AG Baldauf
Topic
n.a.
n. a.
13. May 2024
Results colloquium
Journal club
Speaker
Tanja Maier, AG Kroiß
Stefan Niedermeier, AG Buchner
Topic
n.a.
n. a.
6. May 2024
Results colloquium
Journal club
Speaker
Viola Siegert, AG Buchner
Alexandra Leutbecher, AG Subklewe
Topic
n.a.
n. a.
29. April 2024
Results colloquium
Journal club
Speaker
Alexandra Triebig, AG Kroiß
Linda Hammann, AG Anz
Topic
n.a.
n. a.
22. April 2024
Guest speaker
Speaker
Laurie Menger
Topic
LET'S IMMUN
Systematic discovery of targets improving T-cell therapy using in vivo genome-wide CRISPR screens
8. April 2024
Results colloquium
Journal club
Speaker
Jingke Tu, AG Theurich
Conghui Wang, AG König / Schnurr
Introduction round, Team jobs
The Characteristics of Obesity-Associated NK Cells deriving from Bone Marrow Hematopoietic Stem/Progenitor Cells
findet nicht statt
Winter semester 2023 / 2024
18. März 2024
Guest speaker
Speaker
Dr. Andreas Linder
Topic
The Nobel Prize in Medicine 2023 - Breaktrough of mRNA technology
11. März 2024
Results colloquium
Journal club
Speaker
David Andreu Sanz, AG Kobold
Till Johannsmann, AG Daniel
Topic
RoseTTAFold-generated mini binders replacing scFv for CAR T cell therapy
Universal recording of immune cell interactions in vivo, Nature 2024
04. März 2024
Guest speaker
Journal club
Speaker
Amelie Muth, AG Subklewe
Rasmus Müller, AG Kobold
Topic
Modulating Bispecific Antibody-Mediated T Cell Exhaustion by Exposure to Glucocorticoids
IL-10 expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastases, Nature Biotechnology 2022
26. Februar 2024
Results colloquium
Journal club
Speaker
Dr. Sarah Kim-Hellmuth
Charlotte Carcopino, AG Kobold
Topic
The fascinating effects of genetic diversity on the human immune system and beyond
findet nicht statt
19. Februar 2024
Results colloquium
Journal club
Speaker
Sabine Oganesian, AG Theurich
Mirjam Schobel,
AG Rothenfußer/ Kim-Hellmuth
Topic
Characterization of the Tumormicorenvironment in Cutaneous T cell Lymphoma with a special focus on B cells
findet nicht statt
12. Februar 2024
Results colloquium
Journal club
Speaker
Lisa Gregor, AG Kobold
Sara Egea-Rodriguez, AG Helfrich
Topic
Prostanoid-resistant CAR T cells in cancer
CD4+ T cell immunity against cutaneous melanoma encompasses multifaceted MHC II–dependent responses, Science Immunology 2024
05. Februar 2024
Educational colloquium
Journal club
Speaker
Dr. Anne Holtermann, AG Daniel
Sandra Dirschl, AG Kobold
Topic
findet nicht statt
In vivo human T cell engineering with enveloped delivery vehicles, Nature Biotechnology 2024
22. Januar 2024
Educational colloquium
Journal club
Speaker
Dr. Ignazio Piseddu, AG Anz
Emre Erdogan, AG Kobold
Topic
findet nicht statt
Novel engineered chimeric engulfment receptors trigger T cell effector functions against SIV-infected CD4+ T cells", Molecular Therapy 2023
15. Januar 2024
Guest speaker
Speaker
Larsen Vornholz
Topic
Tumor-cell intrinsic STING signaling controls antitumor immunity
08. Januar 2024
Results colloquium
Journal club
Speaker
Julia Teppert, AG König/ Schnurr
Dr. Matthias Thaler, AG Anz
Topic
Cell death-optimized 5´-triphosphate RNAs for improved tumor immunotherapy
"Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus" Nature Medicine 2022
11. Dezember 2023
Guest speaker
Speaker
Dr. Sarah Kim-Hellmuth
Topic
The fascinating effects of genetic diversity on the human immune system and beyond
04. Dezember 2023
Results colloquium
Journal club
Speaker
Monika Sponheimer, AG Subklewe
Alexandra Leutbecher, AG Subklewe
Topic
The Yin and Yang of Pro-Inflammatory Cytokines in Antibody-based Immunotherapy of AML: TNF-a Increases the Expression of the Leukemia-Associated Antigen CD70, and IFN-g Dampens ADCC by NK Cells
CD47 masks pro-phagocytic ligands in cis on tumor cells to suppress antitumor immunity CD47 masks pro-phagocytic ligands in cis on tumor cells to suppress antitumor immunity, Nature Immunology 2023
27. November 2023
Results colloquium
Journal club
Speaker
Sophie Bernhard, AG Kobold
Dr. Matthias Thaler, AG Anz
Topic
Arming CAR T cells with C-C-motive receptor 8 for cancer treatment
findet nicht statt
20. November 2023
Results colloquium
Journal club
Speaker
Stefan Niedermeier, AG Buchner
Lena Jablonowski, AG Feuchtinger
Topic
Exploring tumor microenvironment remodeling and ferroptosis resistance during Richter transformation
An „Off-the-Shelf“ CD2 universal CAR-T therapy for T-cell malignancies, Leukemia 2023
13. November 2023
Results colloquium
Journal club
Speaker
Till Johannsmann, AG Daniel
Viktoria Hartmann, AG Kobold
Topic
Novel inducers of Treg cells to control autoimmunity such as T1D
Nils Wellhause et al. „Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy“
6. November 2023
Educational colloquium
Journal club
Speaker
Dr. Thu Nguyen, AG Kobold
Lena-Maria Jablonowski, AG Feuchtinger
Topic
Clinical aspects of CAR-T Cell therapy
findet nicht statt
30. Oktober 2023
Results colloquium
Journal club
Speaker
Alejandro Salinas-Illarena, AG Baldauf
Gordon Hoffmann, AG Kobold
Topic
Development of simplified virus-like particles (VLPs) for Vpx delivery to overcome chemotherapy resistance in AML
Co-opting signalling molecules enables logic- gated control of CAR T cells, Nature Cancer 2022
16. Oktober 2023
Results colloquium
Journal club
Speaker
Mara Henrich, AG Kobold
Valerie Kolarik, AG König/ Schnurr
Topic
CAR-T cell therapy in colorectal cancer - Disease specific engineering of CAR-T Cells utilizing chemokine receptors
Swietlik et al: “Cell-selective proteomics segregates pancreatic cancer subtypes by extracellular proteins in tumors and circulation“, Nature Communications 2023
9. Oktober 2023
Guest speaker
Journal club
Speaker
Prof. Dr. Ralf Jungmann
Monika Sponheimer, AG Subklewe
Topic
Localizomics: towards spatial omics using DNA-based super-resolution microscopy
2. Oktober 2023
Results colloquium
Journal club
Speaker
Viola Siegert, AG Buchner
Luana Messa, AG Anz
Topic
Metabolic Reprogramming during the transformation of CLL to aggressive lymphom
Tian et al “Specific targeting of glioblastoma with an oncolytic virus expressing a cetuximab- CCL5 fusion protein via innate and adaptive immunity“, Nature Cancer 2022
25. September 2023
Educational colloquium
Journal club
Speaker
Prof. Matthias Kroiß, AG Kroiß
Shenzhi Jia, AG Rothenfußer
Topic
What endocrine tumours can teach about cancer immunology
//
18. September 2023
Results colloquium
Journal club
Speaker
Tanja Maier, AG Kroiß
Vivien Menkhoff, AG Kobold
Topic
Towards an understanding of the microenvironment of ACC: Impact of steroid hormones and glucocorticoid receptor signaling
//
Summer semester 2023
24. Juli 2023
Results colloquium
Journal club
Speaker
Antonio Santos del Peral, AG Rothenfußer
Till Johannsmann, AG Daniel
Topic
Basal determinatnts of immune variation and response to the yellow fever vaccine
The dietary sweetener sucaralose is a negative modulator of T cell-mediated responses, Nature 2023
17. Juli 2023
Educational colloquium
Journal club
Speaker
Prof. Simon Rothenfußer, AG Rothenfußer
Paul Schwarzlmüller, AG Kroiß
Topic
Lessons to learn from primary immunodeficiencies
Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment
10. Juli 2023
Results colloquium
Journal club
Speaker
Sara Egea-Rodriguez, AG Helfrich
Lina Majed, AG Kobold
Topic
High levels of RECQL4 DNA helicase correlate with low numbers of tumorinfiltrating lymphocytes driving poor clinical outcome in patients of mal
Reprogramming tumour-associated macrophages to outcompete cancer cells, Nature 2023
3. Juli 2023
Educational colloquium
Journal club
Speaker
Dr. Maike Buchner, AG Ruland, AG Buchner
Jingke Tu, AG Theurich
Topic
Signaling thresholds in B cell development an CLL
TGF-β and CIS Inhibition overcomes NK-cell suppression to restore antitumor immunity, Cancer Immunol 2022
26. Juni 2023
Results colloquium
Journal club
Speaker
Phillip Müller, AG Kobold
Lina Majed, AG Kobold
Topic
Engineering of novel CAR T cells - Targeting lung cancer specific structures
How to hold a journal club
(Guideline)
19. Juni 2023
Results colloquium
Journal club
Speaker
Alexandra Triebig, AG Kroiß
Stefan Niedermeier, AG Buchner
Topic
Targeting the Ferroptosis-Macrophage crosstalk in adrenocortical carcinoma (ACC)
Choi et al. Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal anti-tumor immunity, Science Immunology 2023
12 Juni 2023
Guest speaker
Speaker
Prof. Dr. Per Thor Straten
Topic
The exercise of TAMing the immune system
5. Juni 2023
Results colloquium
Journal club
Speaker
Sandra Dirschl, AG Daniel
Mirjam Schobel, AG Rothenfußer und Kim-Hellmuth
Topic
T cell specific miRNA targeting in Type 1 Diabetes
Hagan et al. Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses. Nat Immunol 2022
29. Mai 2023
Public Holiday:
Pfingsten
22. Mai 2023
Results colloquium
Journal club
Speaker
Adriano Carboniero, AG Theurich
Sara Egea-Rodriguez, AG Helfrich
Topic
Metabolic reprogramming of Natural Killer cells by obesity-associated and tumour-derived cytokine networks
Wang et al., STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer, Nature Communications 2022
15. Mai 2023
Results colloquium
Journal club
Speaker
Amelie Muth, AG Subklewe
Alejandra Hernandez Caceres, AG Hopfner
Topic
Lenalidomide in combination with continuous CD3xCD19 T cell recruiting bispecific antibody treatment maintains T cell function and delays exhaustion
Yu, X. et al. Reducing affinity as a strategy to boost immunomodulatory antibody agonism. Nature 2023
8. Mai 2023
Educational colloquium
Journal club
Speaker
Dr. Iman Dalloul, AG Kobold
Alexandra Leutbecher, AG Subklewe
Topic
Canonical Switch in Cis or Trans and IgH Locus Suicide Recombinations
J. Ding et al. Mesothelin targeting T cells bearing a novel T cell receptor fusion construct TRuC exhibit potent antitumor efficacy against solid tumors, OncoImmunology 2023
24. April 2023
Results colloquium introduction round and distribution of team jobs
Speaker
Julia Teppert, AG König and Marx
Topic
Cell death-optimized 5’-triphosphate RNAs for improved tumor immunotherapy
17. April 2023
Results colloquium Kick-off i-Target 2.0
Speaker
Emanuele Carlini, AG Kobold
Topic
Engineering an atypical cytokine signalling into human CSF-1-responsive CAR T cells