Seminar program
i-Target 2.0
Location and Time
Results colloquium or educational colloquium: Monday, 17:00 to 18:00
Journal club: Monday, 18:00 to 18:30
Winter semester 2023
25. September 2023
Educational colloquium
Journal club
Speaker
Prof. Matthias Kroiß, AG Kroiß
Shenzhi Jia, AG Rothenfußer
Topic
What endocrine tumours can teach about cancer immunology
//
18. September 2023
Results colloquium
Journal club
Speaker
Tanja Maier, AG Kroiß
Vivien Menkhoff, AG Kobold
Topic
Towards an understanding of the microenvironment of ACC: Impact of steroid hormones and glucocorticoid receptor signaling
//
Summer semester 2023
24. Juli 2023
Results colloquium
Journal club
Speaker
Antonio Santos del Peral, AG Rothenfußer
Till Johannsmann, AG Daniel
Topic
Basal determinatnts of immune variation and response to the yellow fever vaccine
The dietary sweetener sucaralose is a negative modulator of T cell-mediated responses, Nature 2023
17. Juli 2023
Educational colloquium
Journal club
Speaker
Prof. Simon Rothenfußer, AG Rothenfußer
Paul Schwarzlmüller, AG Kroiß
Topic
Lessons to learn from primary immunodeficiencies
Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment
10. Juli 2023
Results colloquium
Journal club
Speaker
Sara Egea-Rodriguez, AG Helfrich
Lina Majed, AG Kobold
Topic
High levels of RECQL4 DNA helicase correlate with low numbers of tumorinfiltrating lymphocytes driving poor clinical outcome in patients of mal
Reprogramming tumour-associated macrophages to outcompete cancer cells, Nature 2023
3. Juli 2023
Educational colloquium
Journal club
Speaker
Dr. Maike Buchner, AG Ruland, AG Buchner
Jingke Tu, AG Theurich
Topic
Signaling thresholds in B cell development an CLL
TGF-β and CIS Inhibition overcomes NK-cell suppression to restore antitumor immunity, Cancer Immunol 2022
26. Juni 2023
Results colloquium
Journal club
Speaker
Phillip Müller, AG Kobold
Lina Majed, AG Kobold
Topic
Engineering of novel CAR T cells - Targeting lung cancer specific structures
How to hold a journal club
(Guideline)
19. Juni 2023
Results colloquium
Journal club
Speaker
Alexandra Triebig, AG Kroiß
Stefan Niedermeier, AG Buchner
Topic
Targeting the Ferroptosis-Macrophage crosstalk in adrenocortical carcinoma (ACC)
Choi et al. Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal anti-tumor immunity, Science Immunology 2023
12 Juni 2023
Guest speaker
Speaker
Prof. Dr. Per Thor Straten
Topic
The exercise of TAMing the immune system
5. Juni 2023
Results colloquium
Journal club
Speaker
Sandra Dirschl, AG Daniel
Mirjam Schobel, AG Rothenfußer und Kim-Hellmuth
Topic
T cell specific miRNA targeting in Type 1 Diabetes
Hagan et al. Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses. Nat Immunol 2022
29. Mai 2023
Public Holiday:
Pfingsten
22. Mai 2023
Results colloquium
Journal club
Speaker
Adriano Carboniero, AG Theurich
Sara Egea-Rodriguez, AG Helfrich
Topic
Metabolic reprogramming of Natural Killer cells by obesity-associated and tumour-derived cytokine networks
Wang et al., STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer, Nature Communications 2022
15. Mai 2023
Results colloquium
Journal club
Speaker
Amelie Muth, AG Subklewe
Alejandra Hernandez Caceres, AG Hopfner
Topic
Lenalidomide in combination with continuous CD3xCD19 T cell recruiting bispecific antibody treatment maintains T cell function and delays exhaustion
Yu, X. et al. Reducing affinity as a strategy to boost immunomodulatory antibody agonism. Nature 2023
8. Mai 2023
Educational colloquium
Journal club
Speaker
Dr. Iman Dalloul, AG Kobold
Alexandra Leutbecher, AG Subklewe
Topic
Canonical Switch in Cis or Trans and IgH Locus Suicide Recombinations
J. Ding et al. Mesothelin targeting T cells bearing a novel T cell receptor fusion construct TRuC exhibit potent antitumor efficacy against solid tumors, OncoImmunology 2023
24. April 2023
Results colloquium introduction round and distribution of team jobs
Speaker
Julia Teppert, AG König and Marx
Topic
Cell death-optimized 5’-triphosphate RNAs for improved tumor immunotherapy
17. April 2023
Results colloquium Kick-off i-Target 2.0
Speaker
Emanuele Carlini, AG Kobold
Topic
Engineering an atypical cytokine signalling into human CSF-1-responsive CAR T cells