Kobold Lab

I studied Human Medicine at the Heidelberg University and Paris Descartes University. I performed my doctoral thesis in the laboratory of M. Schmitt in Heidelberg. After graduating from medical school, I started my residency in the hematology and oncology department at the University Hospital of the LMU Munich. I joined the working group of M. Subklewe in the field of translational cancer immunology. Since September 2020, I have been a fellow of the DKTK School of Oncology. Due to the support of the Else Kröner-Fresenius Clinician Scientist Program Cancer Immunotherapy and the Munich Clinician Scientist Program (MCSP) I have worked as a postdoctoral researcher in the working group of S. Kobold since April 2021. My ambition is to work as a Clinician Scientist specializing on immunotherapy. I spend most of my free time with my family and friends.

I studied nutritional sciences in Hamburg and Munich. My master´s thesis, which I conducted in Cork/Ireland, focused on the interplay of immune cells and pain receptors in inflammatory bowel diseases. Back in Germany, I entered the field of immune receptor repertoires in the group of Prof. Dr. Mascha Binder where I also obtained my PhD in December 2020. Using high-throughput sequencing and bioinformatic methods we set out to find immune repertoire imprints that help to identify patients who benefit from immune therapies. My research in the group of Prof. Dr. Sebastian Kobold focuses on the identfication of tumor-specific targets and subsequent design and testing of novel immune cell therapies. Future goals include to learn more about our fascinating immune cells and use this knowledge to generate potent treatments from which hopefully many patients can benefit. In my free time I like to do yoga, go running and practice on my keyboard.

I studied General Biology in my bachelor’s during which I investigated mechanisms of epigenetics and the methyltransferase Dnmt1 in the group of H. Leonhardt. Throughout my master’s degree in Human Biology at the LMU I focused on Immunology and Molecular Oncology, where I studied the combined therapeutic benefits of radio- and immunotherapy in cancer in the group of O. Boyman in Zürich, Switzerland. I started my PhD during fall 2021 in the Kobold Lab, where I now work on the development of cellular therapies for solid tumor entities. My free time I mostly spend with friends and family, I like travelling, eating, and enjoying life without a pipette in my hand!

I graduated from King's College London with a Bachelor's in Pharmacology and from ETH Zurich with a Master's in Pharmaceutical Sciences. After conducting my Master Thesis at the University Hospital of Basel, focusing on immunology and cancer immunotherapy, I moved to Munich for my PhD studies.

At LMU, my work is concerned with investigating how to properly harness the function of cytokines to support and improve the efficacy of cellular therapies against cancer via the generation of chimeric cytokine receptors.

I am a biotechnologist from Barcelona with a master’s in biomedical research. During my bachelor's studies, I had the chance to explore very different areas of research, including transcriptomics and embryology. During my master’s degree, I discovered my interest in cancer cell therapy and conducted my master thesis in Coquet lab at Karolinska Institutet in the field of tumor immunology. I am currently part of the Marie Skłodowska-Curie training network for Optimizing Adoptive T Cell Therapy of Cancer (T-OP) and my PhD project aims to improve CAR T cell functionality with cytokine signaling. In my free time I enjoy playing the piano and learning languages.

As I finished my high school diploma in Pforzheim in 2018, my dream came true to study medicine in Bavarian’s metropolitan area Munich. After the preclinical studies at the Luwig-Maximilians-University Munich and the first state examination in summer 2020, I continued the clinical part of my degree at the Technical University of Munich and the Klinikum rechts der Isar. At the DoktaMed 2020, I experienced the KlinPharm and the Kobold lab the first time, and was thrilled of their working spirit and future goals. Fortunately, my time within our group started in August 2021, as my first day was a pretty memorable hike from Schliersee to Tegernsee. To current state, I am working on the roles of cytokines in immune cell crosstalk and cancer progression, in particular the cytokine Interleukin-22 and its influence on metastases spreading. Besides, my work also includes doing immunofluorescence miscrocopy on human lung cancer tissues to ameliorate the understanding of Interleukin-22-secreting cells as well as their interaction partners. This brings me to my goals, to contribute to the everlasting work for improved understanting of cancer and its possible therapies. Concerning the future, it is my goal to further pursue research activities and at the same time clinical work with cancer patients on the university hospital level. After a hard lab day, I love to enjoy the best noodle place in Munich, the Max Beef Noodles Restaurant at the Sendlinger Tor. In addition, if I am not thinking of any lab work or clinical cases, I spent my leisure time pubquizzing with friends, biking in and around Munich, hiking in the alps and playing the guitar to four chord music hits.

I have been a medical student at LMU Munich for nine semesters now and have just started doing research for my doctoral thesis at the AG Kobold lab. I get to study and work on modular CAR T cell therapy which combines CAR T cells with monoclonal antibodies to further improve the efficacy of CAR T cell therapy while also providing the means to regulate CAR T cell function. Aside from my very interesting research topic I also appreciate the friendly and encouraging working atmosphere that is always present in the lab.

After finishing my medical studies, I want to work as a clinician scientist, preferably at LMU Munich.

In my free time I enjoy doing ballet, reading, biking and spending time with my friends and family.