Main Fields of Research
The main focus of our research are the immunological and allergological reactions of patients to – especially metal – implant materials. We cooperate with medical societies (orthopaedic – DGOU; allergy – ESCD, DGAKI; dermatology – DDG, DKG, EADV), international research groups (for example by EADV-grant with Amsterdam, Copenhagen, Basel, Malmö, Prague, Stettin) and implant manufacturers. Our research combines epidemiologic, genetic and experimental data to find and improve new tests and setups for the diagnosis of implant intolerance reactions. A major component of these tests is the “lymphocyte transformation test” (LTT), which we also started to evaluate now for drug hypersensitivity. Another focus are inflammatory mediators and their regulation.
Eva Oppel, MD
PD Burkhard Summer, BSc
Ralf Pohl, BTA
Prof. Peter Thomas, MD
» Kapp F, Summer B, Thomas P. Usefulness of lymphocyte transformation test and in vitro cytokine release in differentiating between independent and cross-reacting nickel/palladium allergy. Immun Inflamm Dis 2020. 8(4):483-492
» Reichl FX, Högg C, Liu F, Schwarz M, Teupser D, Hickel R, Bloch W, Schweikl H, Thomas P, Summer B. Actovegin® reduces PMA-induced inflammationon human cells. Eur J Appl Physiol 2020. 120(7):1671-1680