RG Psychiatric Genetics – IPPG
Research Group Leader: Dr. rer. nat. Sergi Papiol, PhD
Internal Collaborators: Prof. Peter Falkai / Prof. Thomas G. Schulze / Prof. Moritz Rossner
Research Interests: Genomics, polygenicity, biomarker, biobank
One of our main interests is to understand the influence of genetic variants on the expression of psychiatric symptoms and other clinical features. For this purpose, we implement strategies based on polygenic burden or pathway analyses to disentangle the genetic factors that ultimately contribute to the behavioural expression of psychiatric disorders. A second focus of research is the identification of polygenic signatures and peripheral biomarkers suitable for the prediction of clinical outcomes in these patients.
- association studies and risk of mental disease.
- Peripheral biomarkers for the prediction of outcome.
- Polygenic approaches to psychiatric disorders.
- Pathway/enrichment analyses.
- Cross-sectional and longitudinal studies.
- Alternative phenotypes
- Serum Proteome Signatures of the Longitudinal Course in Bipolar Disorder: Implications for Prediction of Clinical Outcome and Response to Pharmacological Treatment over Time.
- Identification of genetic modifiers of the Lithium-response
- Modulatory role of genomics on the interplay between exercise and improvement of Schizophrenia symptoms
- Genetic basis of suicidal behaviour