Key publications

1. Pekayvaz K, Gold C, Hoseinpour P, Engel A, Martinez-Navarro A, Eivers L, Coletti R, Joppich M, Dionísio F, Kaiser R, Tomas L, Janjic A, Knott M, Mehari F, Polewka V, Kirschner M, Boda A, Nicolai L, Schulz H, Titova A, Kilani B, Lorenz M, Fingerle-Rowson G, Bucala R, Enard W, Zimmer R, Weber C, Libby P, Schulz C, Massberg S, Stark K (2023) Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation. Immunity. 2023 Oct 10;56(10):2325-2341.e15.

2. Kaiser R, Gold C, Joppich M, Loew Q, Akhalkatsi A, Mueller TT, Offensperger F, Droste Zu Senden A, Popp O, di Fina L, Knottenberg V, Martinez-Navarro A, Eivers L, Anjum A, Escaig R, Bruns N, Briem E, Dewender R, Muraly A, Akgöl S, Ferraro B, Hoeflinger JKL, Polewka V, Khaled NB, Allgeier J, Tiedt S, Dichgans M, Engelmann B, Enard W, Mertins P, Hubner N, Weckbach L, Zimmer R, Massberg S, Stark K*, Nicolai L*, Pekayvaz K* (2024) Peripheral priming induces plastic transcriptomic and proteomic responses in circulating neutrophils required for pathogen containment (2024). Sci Adv. 2024 Mar 22;10(12):eadl1710. *contributed equally
   

3. Pekayvaz K, Leunig A, Kaiser R, Joppich M, Brambs S, Janjic A, Popp O, Nixdorf D, Fumagalli V, Schmidt N, Polewka V, Anjum A, Knottenberg V, Eivers L, Wange LE, Gold C, Kirchner M, Muenchhoff M, Hellmuth JC, Scherer C, Rubio-Acero R, Eser T, Deák F, Puchinger K, Kuhl N, Linder A, Saar K, Tomas L, Schulz C, Wieser A, Enard W, Kroidl I, Geldmacher C, von Bergwelt-Baildon M, Keppler OT, Munschauer M, Iannacone M, Zimmer R, Mertins P, Hubner N, Hoelscher M, Massberg S, Stark K*, Nicolai L* (2022). Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection. Nat. commun. 2022 Feb 23;13(1):1018. *contributed equally
   

4. Pekayvaz K, Losert C, Knottenberg V, Gold C, V. van Blokland I, Oelen R, E. Groot E, Walter Benjamins J, Brambs S, Kaiser R, Gottschlich A, Hoffmann G, Eivers L, Martinez-Navarro A, Bruns N, Stiller S, Akgöl S, Yue K, Polewka V, Escaig R, Joppich M, Janjic A, Popp O, Kobold S, Stark K (2024) Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes. Nat Med (2024)
   

Selected publications

1. Kaiser R*, Leunig A*, Pekayvaz K*, Popp O, Joppich M, Polewka V, Escaig R, Anjum A, Hoffknecht ML, Gold C, Brambs S, Engel A, Stockhausen S, Knottenberg V, Titova A, Haji M, Scherer C, Muenchhoff M, Hellmuth JC, Saar K, Schubert B, Hilgendorff A, Schulz C, Kääb S, Zimmer R, Hübner N, Massberg S, Mertins P, Nicolai L, Stark K (2021)Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19.JCI Insight. 2021 Sep 22;6(18):e150862.* contributed equally

2. Stark K, Massberg S. (2021) Interplay between inflammation and thrombosis in cardiovascular pathology. 2021Nat Rev Cardiol. 2021 Sep;18(9):666-682. (LMU -Paper of the Month September 2021)

3. Nicolai L, Leunig A, Brambs S, Kaiser R, Joppich M, Hoffknecht ML, Gold C, Engel A, Polewka V, Muenchhoff M, Hellmuth JC, Ruhle A, Ledderose S, Weinberger T, Schulz H, Scherer C, Rudelius M, Zoller M, Keppler OT, Zwißler B, von Bergwelt-Baildon M, Kääb S, Zimmer R, Bülow RD, von Stillfried S, Boor P, Massberg S, Pekayvaz K*, Stark K* (2021) Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID-19 from influenza pneumonia.J Thromb Haemost. 2021 Feb;19(2):574-581.* contributed equally

4. Nicolai L, Leunig A, Brambs S, Kaiser R, Weinberger T, Weigand M, Muenchhoff M, Hellmuth JC, Ledderose S, Schulz H, Scherer C, Rudelius M, Zoller M, Höchter D, Keppler O, Teupser D, Zwißler B, von Bergwelt-Baildon M, Kääb S, Massberg S, Pekayvaz K*, Stark K*(2020) Immunothrombotic Dysregulation in COVID-19 Pneumonia Is Associated With Respiratory Failure and Coagulopathy. Circulation. 22;142(12):1176-1189.(DZHK - Paper of the Month August 2020)* contributed equally

5. Marx C, Novotny J, Salbeck D, Zellner K R, Nicolai L, Pekayvaz K, Kilani B, Stockhausen S, Bürgener N, Kupka D, Stocker T J, Weckbach L T, Pircher J, Moser M, Joner M, Desmet W, Adriaenssens T, Neumann F-J, Gerschlick A H, Ten Berg J M, Lorenz M, Stark K (2019) Eosinophil-platelet interactions promote atherosclerosis and stabilize thrombosis with eosinophil extracellular traps. Blood. 21;134(21):1859-1872.
6. Stark K, Philippi V, Stockhausen S, Busse J, Antonelli A, Miller M, Schubert I, Hoseinpour P, Chandraratne S, von Brühl ML, Gaertner F, Lorenz M, Agresti A, Coletti R, Antoine DJ, Heermann R, Jung K, Reese S, Laitinen I, Schwaiger M, Walch A, Sperandio M, Nawroth PP, Reinhardt C, Jäckel S, Bianchi ME, Massberg S. (2016) Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice. Blood. 28(20):2435-2449
7. Stark K, Eckart A, Haidari S, Tirniceriu A, Lorenz M, von Brühl ML, Gärtner F, Khandoga AG, Legate KR, Pless R, Hepper I, Lauber K, Walzog B, Massberg S. (2013) Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs. Nature Immunology 14(1):41-51.
8. von Brühl ML*, Stark K*, Steinhart A, Chandraratne S, Konrad I, Lorenz M, Khandoga A, Tirniceriu A, Coletti R, Köllnberger M, Byrne RA, Laitinen I, Walch A, Brill A, Pfeiler S, Manukyan D, Braun S, Lange P, Riegger J, Ware J, Eckart A, Haidari S, Rudelius M, Schulz C, Echtler K, Brinkmann V, Schwaiger M, Preissner KT, Wagner DD, Mackman N, Engelmann B, Massberg S. (2012) Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo. Journal of Experimental Medicine. 209(4):819-35 * contributed equally