AG Hausleiter
High-grade insufficiencies of the mitral and tricuspid valves are associated with increased morbidity and mortality. In our ageing society, mitral and tricuspid valve insufficiencies are on the rise. As the majority of patients with this disease are older and often have relevant concomitant diseases, surgical treatment can be associated with an increased risk. For this reason, minimally invasive, catheter-based therapy is becoming increasingly common for these patients in order to minimize the risk of surgery.
The aim of the working group is to develop and establish interventional treatment alternatives for the relevant mitral and tricuspid valve insufficiency.
Another focus is on research into innovative treatment methods for patients with heart failure.
As a certified mitral valve center of the DGK (German Society of Cardiology), we meet all requirements to participate in numerous national and international studies. These include treatment with the MitraClip system, Pascal system and catheter-based mitral and tricuspid valve replacement. For heart failure monitoring and therapy optimization, we also offer the new V-LAP system and the Relieve HF/V-Wave atrial shunt as part of studies.
- "Prospective Randomized Trial on Radiation Dose Estimates of CT Angiography Applying Iterative Image Reconstruction: The PROTECTION V Study." Deseive S, Chen MY, Korosoglou G, Leipsic J, Martuscelli E, Carrascosa P, Mirsadraee S, White C, Hadamitzky M, Martinoff S, Menges AL, Bischoff B, Massberg S, Hausleiter J. JACC Cardiovasc Imaging. 2015 Aug;8(8):888-96
- "Patient selection, echocardiographic screening and treatment strategies for interventional tricuspid repair using the edge-to-edge repair technique." Hausleiter J, Braun D, Orban M, Latib A, Lurz P, Boekstegers P, von Bardeleben RS, Kowalski M, Hahn RT, Maisano F, Hagl C, Massberg S, Nabauer M EuroIntervention. 2018 Aug 20;14(6):645-653
- "Reduction in radiation exposure in cardiovascular computed tomography imaging: results from the PROspective multicenter registry on radiaTion dose Estimates of cardiac CT angIOgraphy iN daily practice in 2017 (PROTECTION VI)." Stocker TJ, Deseive S, Leipsic J, Hadamitzky M, Chen MY, Rubinshtein R, Heckner M, Bax JJ, Fang XM, Grove E, Lesser J, Maurovich-Horvat P, Otton J, Shin S, Pontone G, Marques H, Chow B, Nomura CH, Tabbalat R, Schmermund A, Kang JW, Naoum C, Atkins M, Martuscelli E, Massberg S, Hausleiter J; PROTECTION VI investigators Eur Heart J. 2018 Nov 1;39(41):3715-3723
- "Transcatheter Edge-to-Edge Repair for Tricuspid Regurgitation Is Associated With Right Ventricular Reverse Remodeling in Patients With Right-Sided Heart Failure." Orban M, Braun D, Deseive S, Stolz L, Stocker TJ, Stark K, Stremmel C, Orban M, Hagl C, Massberg S, Hahn RT, Nabauer M, Hausleiter J. JACC Cardiovasc Imaging. 2019 Mar;12(3):559-560
- "1-Year Outcomes After Edge-to-Edge Valve Repair for Symptomatic Tricuspid Regurgitation: Results From the TriValve Registry." Mehr M, Taramasso M, Besler C, Ruf T, Connelly KA, Weber M, Yzeiraj E, Schiavi D, Mangieri A, Vaskelyte L, Alessandrini H, Deuschl F, Brugger N, Ahmad H, Biasco L, Orban M, Deseive S, Braun D, Rommel KP, Pozzoli A, Frerker C, Näbauer M, Massberg S, Pedrazzini G, Tang GHL, Windecker S, Schäfer U, Kuck KH, Sievert H, Denti P, Latib A, Schofer J, Nickenig G, Fam N, von Bardeleben S, Lurz P, Maisano F, Hausleiter J. JACC Cardiovasc Interv. 2019 Aug 12;12(15):1451-1461
- "Compassionate Use of the PASCAL Transcatheter Valve Repair System for Severe Tricuspid Regurgitation: A Multicenter, Observational, First-in-Human Experience." Fam NP, Braun D, von Bardeleben RS, Nabauer M, Ruf T, Connelly KA, Ho E, Thiele H, Lurz P, Weber M, Nickenig G, Narang A, Davidson CJ, Hausleiter J. JACC Cardiovasc Interv. 2019 Dec 23;12(24):2488-2495
- "Combined Tricuspid and Mitral Versus Isolated Mitral Valve Repair for Severe MR and TR: An Analysis From the TriValve and TRAMI Registries." Mehr M, Karam N, Taramasso M, Ouarrak T, Schneider S, Lurz P, von Bardeleben RS, Fam N, Pozzoli A, Lubos E, Boekstegers P, Schillinger W, Plicht B, Eggebrecht H, Baldus S, Senges J, Maisano F, Hausleiter J; TriValve and TRAMI Investigators JACC Cardiovasc Interv. 2020 Mar 9;13(5):543-550
- "Transcatheter Edge-to-Edge Tricuspid Repair for Severe Tricuspid Regurgitation Reduces Hospitalizations for Heart Failure." Orban M, Rommel KP, Ho EC, Unterhuber M, Pozzoli A, Connelly KA, Deseive S, Besler C, Ong G, Braun D, Edwards J, Miura M, Gülmez G, Stolz L, Gavazzoni M, Zuber M, Orban M, Nabauer M, Maisano F, Thiele H, Massberg S, Taramasso M, Fam NP, Lurz P, Hausleiter J JACC Heart Fail. 2020 Apr;8(4):265-276
- "Value of Echocardiographic Right Ventricular and Pulmonary Pressure Assessment in Predicting Transcatheter Tricuspid Repair Outcome." Karam N, Mehr M, Taramasso M, Besler C, Ruf T, Connelly KA, Weber M, Yzeiraj E, Schiavi D, Mangieri A, Vaskelyte L, Alessandrini H, Deuschl F, Brugger N, Ahmad H, Ho E, Biasco L, Orban M, Deseive S, Braun D, Gavazzoni M, Rommel KP, Pozzoli A, Frerker C, Näbauer M, Massberg S, Pedrazzini G, Tang GHL, Windecker S, Schäfer U, Kuck KH, Sievert H, Denti P, Latib A, Schofer J, Nickenig G, Fam N, von Bardeleben S, Lurz P, Maisano F, Hausleiter J JACC Cardiovasc Interv. 2020 May 25;13(10):1251-1261
- "Impact of Proportionality of Secondary Mitral Regurgitation on Outcome After Transcatheter Mitral Valve Repair." Orban M, Karam N, Lubos E, Kalbacher D, Braun D, Deseive S, Neuss M, Butter C, Praz F, Kassar M, Petrescu A, Pfister R, Iliadis C, Unterhuber M, Lurz P, Thiele H, Baldus S, Stephan von Bardeleben R, Blankenberg S, Massberg S, Windecker S, Hausleiter J; EuroSMR Investigators JACC Cardiovasc Imaging. 2020 Aug 24:S1936-878X(20)30620-3; Online ahead of print
Prof. Dr. med. Jörg Hausleiter
PI
Medical team
Prof. Dr. med. Michael Näbauer
PD Dr. med. Thomas Stocker
PD Dr. med. Ludwig Weckbach
PD Dr. med. Simon Deseive
Dr. med. Lukas Stolz
Study team
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