Medical Clinic and Polyclinic I
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AG Orban/Scherer

Cardiogenic shock and medical informatics

In Germany, cardiogenic shock is the most common cause of death among heart attack patients in hospital. Despite new treatment concepts, the mortality rate in hospital for this patient group has not improved significantly in the last decade and remains at around 50%.

The Heart Team at the LMU Clinic, consisting of doctors from cardiology and cardiac surgery, treats around 100 to 200 patients with this clinical picture every year, including the use of mechanical cardiovascular support systems, making it one of the largest centers in Europe.

Many therapeutic concepts in the treatment of cardiogenic shock, such as drug therapy with catecholamines or the use of the mechanical circulatory support system veno-arterial extra-corporeal membrane oxygenation (VA-ECMO, synonymously also extra-coporeal life support, ECLS), have not yet been investigated in larger controlled, randomized clinical trials.

It is therefore all the more important to examine this patient population more closely in prospective registries. The early detection and thus treatment of complications in intensive care units is an important measure for improving the prognosis, even with the use of artificial intelligence. For this reason, our working group has established the so-called LMUshock Registry over several years, in which patients with cardiogenic shock and/or after cardiopulmonary resuscitation are included (WHO study number: DRKS00015860). More than 1100 patients have already been included in the LMUshock registry.

Our working group is also involved in international randomized studies such as the EURO-SHOCK study.

LMU Klinikum
Originally translated with DeepL